Results 81 to 90 of about 626,083 (211)

Expression profiling of miRNA-145 and miRNA-338 in serum and sputum of patients with COPD, asthma, and asthma–COPD overlap syndrome phenotype

International Journal of COPD, 2017
Donato Lacedonia,* Grazia Pia Palladino,* Maria Pia Foschino-Barbaro, Giulia Scioscia, Giovanna Elisiana Carpagnano Department of Medical and Surgical Sciences, Institute of Respiratory Diseases, University of Foggia, Foggia, Italy *These authors ...
Lacedonia D, Palladino GP, Foschino-Barbaro MP, Scioscia G, Carpagnano GE   +4 more
doaj  

The Global Airways Unit: A Multidisciplinary Strategy for Early Diagnosis and Comorbidity Detection

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic respiratory diseases impose a large global burden of morbidity, mortality, and cost. The concept of a global airway has become increasingly supported by epidemiologic, mechanistic, and clinical evidence. However, clinical care often remains fragmented between ear, nose, and throat (ENT), allergy, and pulmonology.
Diego M. Conti, Eduardo J. Correa, Alfonso Del Cuvillo, José D. Abdullatif, Francisco J. Alvarez‐Gutiérrez, Remedios Cárdenas Contreras, Stefan Cimbollek, Rocío Corrales Millán, Ana Gómez‐Bastero Fernández, Daniel Pérez‐Chada, Francisco Pérez‐Grimaldi, Alberto E. Rabino, Maria A. Romero‐Falcón, Marcela Soria, José Gregorio Soto‐Campos, Rosario B. Spuches, Juan Maza‐Solano   +16 more
wiley   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Smoking history and emphysema in asthma–COPD overlap

, 2017
Kazuyoshi Kurashima,1 Yotaro Takaku,1 Chie Ohta,1 Noboru Takayanagi,1 Tsutomu Yanagisawa,1 Tetsu Kanauchi,2 Osamu Takahashi3 1Department of Respiratory Medicine, 2Department of Radiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, 3Center ...
Yanagisawa T, Kurashima K, Kanauchi T, Ohta C, Takayanagi N, Takaku Y, Takahashi O   +6 more
core  

Measuring burden of disease in both asthma and COPD by merging the ACQ and CCQ: less is more?

npj Primary Care Respiratory Medicine
Symptoms of asthma and COPD often overlap, and both diseases can co-exist in one patient. The asthma control questionnaire (ACQ) and clinical COPD questionnaire (CCQ) were developed to assess disease burden in respectively asthma or COPD.
Liz J. A. Cuperus, Cathelijne M. van Zelst, Huib A. M. Kerstjens, Rudi W. Hendriks, Maureen P. M. H. Rutten-van Molken, Jacqueline B. Muilwijk-Kroes, Gert-Jan Braunstahl, Johannes C. C. M. in ’t Veen   +7 more
doaj   +1 more source

Hypercapnia Induces Mitochondrial Adaptations and Alters Glutamine Metabolism to Drive a Distinct Metabolic Phenotype in Monocytes

Immunology &Cell Biology, EarlyView.
Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan, David E. Phelan, Xiaofei Yin, Lorraine Brennan, Martina Wallace, Eoin P. Cummins   +5 more
wiley   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Use of clinical characteristics to predict spirometric classification of obstructive lung disease

International Journal of COPD, 2018
Steven J Pascoe,1 Wei Wu,2,3 Kathryn A Collison,1 Linda M Nelsen,4 Keele E Wurst,5 Laurie A Lee6 1Respiratory Medicines Development Center, GSK, Research Triangle Park, NC, USA; 2Biostatistics, PAREXEL International, Research Triangle Park, NC, USA ...
Pascoe SJ, Wu W, Collison KA, Nelsen LM, Wurst KE, Lee LA   +5 more
doaj  

Clinical Characteristics and Outcomes of Patients with Asthma–COPD Overlap in Japanese Patients with COPD

International Journal of COPD, 2020
Seiichi Kobayashi,1 Masakazu Hanagama,1 Masatsugu Ishida,1 Manabu Ono,1 Hikari Sato,1 Shinsuke Yamanda,1,2 Masaru Yanai1 1Department of Respiratory Medicine, Japanese Red Cross Ishinomaki Hospital, Ishinomaki, Miyagi, Japan; 2Department of Pulmonary ...
Kobayashi S, Hanagama M, Ishida M, Ono M, Sato H, Yamanda S, Yanai M   +6 more
doaj  

Association Between Periodontitis and Respiratory Diseases: A Systematic Umbrella Meta‐Analysis

Oral Diseases, EarlyView.
ABSTRACT Aim This study aimed to evaluate the association between periodontitis and respiratory diseases using an umbrella meta‐analysis. Methods Meta‐analyses (MAs) reporting odds ratios (OR) and mean differences (MD) for the association between periodontitis and respiratory diseases of COVID‐19, chronic obstructive pulmonary disease (COPD), asthma ...
Shahen Hiwa Omer, Mohammed Khalid Mahmood, Sarhang Sarwat Gul, Yad Mariwan Mohammed Amin, Romain Lan   +4 more
wiley   +1 more source