Insulin-like growth factor I in cultured rat astrocytes: expression of the gene, and receptor tyrosine kinase. [PDF]
Robert Ballotti+6 more
openalex +1 more source
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development
The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao+9 more
wiley +1 more source
Acetoacetate and glucose as substrates for lipid synthesis by rat brain oligodendrocytes and astrocytes in serum-free culture [PDF]
Jan W. Koper+3 more
openalex +1 more source
Dynamic Pathophysiological Insight into the Brain by NIR‐II Imaging
The functional integration of benefits from small semiconducting dyes and biocompatible serum proteins ushered in a new frontier of deep wide‐field in vivo imaging technique, affording valuable pathophysiological insight into the functioning of neurovascular unit in space and time.
Si Chen+9 more
wiley +1 more source
Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1
Summary: Circadian clock dysfunction is a common symptom of aging and neurodegenerative diseases, though its impact on brain health is poorly understood. Astrocyte activation occurs in response to diverse insults and plays a critical role in brain health
Brian V. Lananna+15 more
doaj
Astrocyte scar formation aids central nervous system axon regeneration
Mark A. Anderson+9 more
semanticscholar +1 more source
Use of an in vitro system to study the effects of lead on astrocyte-endothelial cell interactions: A model for studying toxic injury to the blood-brain barrier [PDF]
Ann Marie Gebhart, Gary W. Goldstein
openalex +1 more source
Network‐based risk stratification of people living with HIV (PWH) on prolonged therapy using multi‐omics data identifies 44% of the patients are at risk of immunometabolic complications. A senescence‐associated myeloid cell‐driven plasma microenvironment drives immunometabolic dysregulation in at‐risk PWH.
Flora Mikaeloff+32 more
wiley +1 more source
Heparin inhibits the growth of astrocytes in vitro [PDF]
Patricia L. Robertson, Gary W. Goldstein
openalex +1 more source
Endothelial PD‐1 Regulates Vascular Homeostasis and Oligodendrogenesis during Brain Development
Vascular endothelial cells are fundamental for angiogenesis and brain development. This study reveals that endothelial programmed cell death 1 (PD‐1) is critical for cerebral angiogenesis and blood brain barrier (BBB) maturation. It also mediates interaction with oligodendrocyte precursor cells (OPCs), modulating OPCs differentiation and myelination ...
Tingting He+7 more
wiley +1 more source