Results 251 to 260 of about 124,424 (305)

Descriptive Epidemiology From the Myhre Syndrome Foundation Registry: The Value of Self‐Reported Data

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is an ultrarare genetic disease characterized by short stature, distinct craniofacial features, cardiovascular and respiratory fibrosis and stenosis, neurodevelopmental delays, autism, intellectual disability, and hearing loss. The natural history of Myhre syndrome is still not fully understood due to a small patient population ...
Mary K. Young, Armelle Pindon, Maggie R. Brand, Kate Wears, Katherine H. Young, Alyssa Mendel, Michael J. Lyons   +6 more
wiley   +1 more source

Astrocyte-Neuron Crosstalk in Hypertension: Mechanisms and Therapeutic Significance. [PDF]

Rev Cardiovasc Med
Zhao M, Jia H, Li N.
europepmc   +1 more source

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

Animal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao, Chunlan Zou, Junxian Li, Yang Yang, Yuanyuan Han, Tingyu Ke   +5 more
wiley   +1 more source

The Small Chemical Compound Repsox Potentiates Oct4-Driven Astrocyte-to-Neural Stem Cell Reprogramming via Notch1/Hes1/Smurf2 Pathway. [PDF]

Cell Mol Neurobiol
Ma X, Liu Z, He Y, Zhang D, Deng P, Li L, Li X, Li J, Ma Q, Yang H.   +9 more
europepmc   +1 more source

Scalp electroacupuncture targeting trigeminal nerve activation alleviates post‐traumatic stress disorder–induced depression and neuroinflammation in mice

Animal Models and Experimental Medicine, EarlyView.
Scalp electroacupuncture (SA) through activation of the trigeminal pathway exerts anti‐inflammatory, antidepressant, and anxiolytic effects in an animal model of post‐traumatic stress disorder induced by single prolonged stress. This suggests that SA is involved in neuroinflammation and changes in brain‐derived neurotrophic factor protein through the ...
Bombi Lee, Yoongeun Kim, Hyungjun Kim, Dae‐Hyun Hahm   +3 more
wiley   +1 more source

Exposure to fibrillar proteins leads to widespread infiltration but only mild tau pathology in cortical organoids. [PDF]

iScience
Dakhel A, Mothes T, Eltom K, Michno WP, Erlandsson A.   +4 more
europepmc   +1 more source

Astrocyte States in Brain Aging and Neurodegeneration: At the Crossroads of Senescence and Reactivity. [PDF]

Neurochem Res
Pacca-Corrêa JBL, Fernandes BM, Siqueira M, Schafbenker R, Baumart GJ, Damico IV, Gomes FCA, Matias I.   +7 more
europepmc   +1 more source

A high-throughput screening platform to facilitate treatment development in Rett syndrome. [PDF]

Front Neurol
Yin Y, Wang A, Dong Q, Zhang Z, Bu Q, Wang R, Chang Q.   +6 more
europepmc   +1 more source

Curing the brain: in search for new astrocyte-specific therapies. [PDF]

Exp Mol Med
Verkhratsky A, Lee CJ, Chun H, Göritz C, Harkany T, Lee JH, Lee S, Lindskog M, Koh W, Mulder J, Nam MH, Ottersen OP, Pekna M, Pekny M, Pękowska A, Ryu H, Sohn CH, Tretiakov EO, Untiet V, Viney TJ, Youn W, Yi C, Zorec R, Yun M, Cheong E, Nordberg A.   +25 more
europepmc   +1 more source