Results 131 to 140 of about 273,908 (305)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Blood‐based biomarkers are increasingly used to identify Alzheimer's disease (AD) pathology and may play an important role in early disease screening and participant selection for clinical trials. However, their performance across stages of cognitive impairment remains unclear. This study examined whether plasma biomarkers differ in
Maryam Abdolmaleki +7 more
wiley +1 more source
Implantable Ionic Memristors Based on Natural Polymer Heterojunctions
Advanced Functional Materials, EarlyView.We report an implantable natural polymer‐based ionic memristor composed of hyaluronic acid, chitosan, and PDMS. The device achieved 98.94% accuracy in MNIST classification while reducing training time by 36.8% compared with a conventional artificial neural network (ANN).
Dong‐yup Lee +6 more
wiley +1 more source
Functional duality of astrocytes in myelination
, 2011 Astrocytes undergo major phenotypic changes in response to injury and disease that directly influence repair in the CNS, but the mechanisms involved are poorly understood. Previously, we have shown that neurosphere-derived rat astrocytes plated on poly-L-
McClure, J.D. +13 more
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Advanced Functional Materials, EarlyView.Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou +6 more
wiley +1 more source
, 2008 The aim of this study was to investigate reactive changes of astrocytes and Muller glial cells in rats subjected to kainate treatment, which leads to neuronal degeneration in the ganglion cell layer and the inner border of the inner nuclear layer as ...
CHANG, MIN-LIN;WU, CHING-HSIANG;JIANG-SHIEH, YA-FEN;SHIEH, JENG-YUNG;WEN, CHEN-YUAN;WEN, CHEN-YUAN +1 more
core
β-Amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase [PDF]
, 2004 β-Amyloid (βA) peptide is strongly implicated in the neurodegeneration underlying Alzheimer's disease, but the mechanisms of neurotoxicity remain controversial. This study establishes a central role for oxidative stress by the activation of NADPH oxidase
Abramov, A.Y. +2 more
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Protoplasmic Astrocytes Are Poorly Understood Cells in Adult Human Brain Tissue
NeurogliaBackground/Objectives: The traditional classification of astrocytes was based on morphological differences between astrocytes and their location in brain tissue.
Ivana Sivakova +2 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A geometry‐reconfigured additive manufacturing strategy converts planar printed soft materials into soft compact neural probes with integrated hydrogel electrodes and microfluidic channels. The resulting NeuroMAP platform enables scalable multichannel recording, localized chemical delivery, stable in vivo electrophysiological recording, and reduced ...
Hyunjin Lee +15 more
wiley +1 more source
Astrocytes Remember Inflammation [PDF]
Astrocytes respond to all forms of central nervous system maladies. In a recent issue of Nature, Lee et al. demonstrate that astrocytes encode inflammatory stimuli as epigenetic memory, which strengthens responses to subsequent stimuli and exacerbates ...
Deneen, Benjamin, Williamson, Michael R
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, 2020 The accumulation of amyloid-β (Aβ) in the walls of capillaries and arteries as cerebral amyloid angiopathy (CAA) is part of the small vessel disease spectrum, related to a failure of elimination of Aβ from the brain.
Roy Oliver Weller +15 more
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