Results 161 to 170 of about 461,223 (386)

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

Spinal astrocyte-derived interleukin-17A promotes pain hypersensitivity in bone cancer mice

Acta Pharmaceutica Sinica B
Spinal microglia and astrocytes are both involved in neuropathic and inflammatory pain, which may display sexual dimorphism. Here, we demonstrate that the sustained activation of spinal astrocytes and astrocyte-derived interleukin (IL)-17A promotes the ...
Huizhu Liu, Xuejing Lv, Xin Zhao, Lanxing Yi, Ning Lv, Wendong Xu, Yuqiu Zhang   +6 more
doaj   +1 more source

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng   +10 more
wiley   +1 more source

Preparation of astrocytes by directed differentiation of pluripotent stem cells and somatic cell transdifferentiation [PDF]

, 2023
Hangjie Chen, Kang Zheng, Mengsheng Qiu, Junlin Yang   +3 more
openalex   +1 more source

Thermally Drawn Multifunctional All‐Hydrogel Fibers for Anti‐Fibrotic and Multimodal Neural Interfaces

Advanced Materials, EarlyView.
Hydrogels demonstrate material properties that mimic the mechanical and chemical environments of biological tissues. Yet, they face challenges during their integration into 3D interfaces. By identifying a class of thermoplastic hydrogels, a strategy is developed to pattern hydrogels in thermally drawn fibers.
Changhoon Sung, Kum Seok Nam, Yeji Kim, Honey Kang, Kanghyeon Kim, Chanwoong Yoon, Somin Lee, Ain Chung, Jiheong Kang, Young‐Gyun Park, Alan Jung Park, Haider Butt, Hyunwoo Yuk, Seongjun Park   +13 more
wiley   +1 more source

Modelling the injured spinal cord using 3-dimensional cell cultures; strategies for improving tissue engineered repair [PDF]

, 2007
not ...
East, E., Golding, J. P., Phillips, J. B.   +2 more
core  

Enriched Environment Inhibits Neurotoxic Reactive Astrocytes Via Jak2-Stat3 to Promote Glutamatergic Synaptogenesis and Cognitive Improvement in Chronic Cerebral Hypoperfusion Rats

, 2023
Bin Fan, Junbin Lin, Qihang Luo, Weijing Liao, Chizi Hao   +4 more
openalex   +1 more source

Astrocytes in the initiation and progression of epilepsy

Nature Reviews Neurology, 2022
A. Vezzani, T. Ravizza, Peter Bedner, E. Aronica, C. Steinhäuser, D. Boison   +5 more
semanticscholar   +1 more source

Macrophages Mediate Mesoscale Brain Mechanical Homeostasis

Advanced Materials, EarlyView.
We investigated the role of infiltrating immune cells in sculpting the developing brain. Using Brillouin microscopy and active microrheology, we found microglia actively maintain tissue viscoelasticity. Moreover, colony stimulating factor one receptor (CSF1R)‐driven stromal remodeling alters brain mechanics in vivo. These findings link immune activity,
Woong Young So, Bailey Johnson, Patricia B. Gordon, Kevin S. Bishop, Hyeyeon Gong, Hannah A Burr, Jack Rory Staunton, Chenchen Handler, Khanh Loan Ly, Raman Sood, Giuliano Scarcelli, Kandice Tanner   +11 more
wiley   +1 more source

Computational Astrocyence: Astrocytes encode inhibitory activity into the frequency and spatial extent of their calcium elevations

, 2019
Deciphering the complex interactions between neurotransmission and astrocytic $Ca^{2+}$ elevations is a target promising a comprehensive understanding of brain function.
Ivanov, Vladimir A., Michmizos, Konstantinos P., Polykretis, Ioannis E.   +2 more
core   +1 more source