Results 171 to 180 of about 123,114 (319)

Chronic, Battery‐Free, Fully Implantable Multimodal Spinal Cord Stimulator for Pain Modulation in Small Animal Models

Advanced Science, EarlyView.
This work introduces wireless‐powered fully implantable spinal cord stimulation (SCS) in freely moving animal models, supporting diverse ethological paradigms. kHz stimulation with real‐time digital programming offers versatile, dynamically optimized therapy. Scalable fabrication ensures high N studies and seamless translation.
Allie J. Widman, Taron Bashar, Alex Burton, David Marshall Clausen, Prashant Gupta, Drew K. Wolf, Jakayla Folarin‐Hines, Maria Payne, John A Rogers, Kathleen W. Meacham, Robert W. Gereau, Philipp Gutruf   +11 more
wiley   +1 more source

PAF‐induced inflammatory and immuno‐allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects

BioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022
Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley   +1 more source

Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes

Nature, 2021
L. Sanmarco, Michael A. Wheeler, Cristina Gutiérrez-Vázquez, C. M. Polonio, M. Linnerbauer, Felipe A. Pinho-Ribeiro, Zhaorong Li, Federico Giovannoni, Katelyn V. Batterman, Giulia Scalisi, Stephanie E. J. Zandee, E. Heck, Moneera Alsuwailm, D. Rosene, B. Becher, I. Chiu, A. Prat, F. Quintana   +17 more
semanticscholar   +1 more source

Insulin-like growth factor I in cultured rat astrocytes: expression of the gene, and receptor tyrosine kinase. [PDF]

, 1987
Robert Ballotti, Finn Cilius Nielsen, Nigel P. Pringle, Aline Kowalski, William D. Richardson, Ellen Van Obberghen‐Schilling, Steen Gammeltoft   +6 more
openalex   +1 more source

RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development

Advanced Science, EarlyView.
The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao, Tianxiang Tang, Bowen Wang, Shengfei He, Yue Zhang, Li Dong, Bo Xu, Ying Liu, Ping Zhu, Rui Guo   +9 more
wiley   +1 more source

Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease

Stem Cell Reports, 2019
Summary: Parkinson's disease (PD) is associated with the degeneration of ventral midbrain dopaminergic neurons (vmDAns) and the accumulation of toxic α-synuclein. A non-cell-autonomous contribution, in particular of astrocytes, during PD pathogenesis has
Angelique di Domenico, Giulia Carola, Carles Calatayud, Meritxell Pons-Espinal, Juan Pablo Muñoz, Yvonne Richaud-Patin, Irene Fernandez-Carasa, Marta Gut, Armida Faella, Janani Parameswaran, Jordi Soriano, Isidro Ferrer, Eduardo Tolosa, Antonio Zorzano, Ana Maria Cuervo, Angel Raya, Antonella Consiglio   +16 more
doaj  

Acetoacetate and glucose as substrates for lipid synthesis by rat brain oligodendrocytes and astrocytes in serum-free culture [PDF]

, 1984
Jan W. Koper, Elly C. Zeinstra, Matthijs Lopes‐Cardozo, L.M.G. Van Golde   +3 more
openalex   +1 more source

Dynamic Pathophysiological Insight into the Brain by NIR‐II Imaging

Advanced Science, EarlyView.
The functional integration of benefits from small semiconducting dyes and biocompatible serum proteins ushered in a new frontier of deep wide‐field in vivo imaging technique, affording valuable pathophysiological insight into the functioning of neurovascular unit in space and time.
Si Chen, Hao Chen, Xinxin Li, Shuqing He, Kangquan Shou, Kun Qian, Zhao Fang, Feng Gu, Baisong Chang, Zhen Cheng   +9 more
wiley   +1 more source

MAFG-driven astrocytes promote CNS inflammation

Nature, 2020
Michael A. Wheeler, I. Clark, Emily C. Tjon, Zhaorong Li, Stephanie E. J. Zandee, C. Couturier, Brianna R. Watson, Giulia Scalisi, Sarah Alkwai, V. Rothhammer, A. Rotem, J. Heyman, Shravan Thaploo, L. Sanmarco, J. Ragoussis, D. Weitz, K. Petrecca, J. Moffitt, B. Becher, J. Antel, A. Prat, F. Quintana   +21 more
semanticscholar   +1 more source

The restoration of REST inhibits reactivity of Down syndrome iPSC-derived astrocytes

Frontiers in Molecular Neuroscience
IntroductionAccumulating evidence indicates that the increased presence of astrocytes is fundamentally linked to the neurological dysfunctions observed in individuals with Down syndrome (DS).
Tan Huang, Sharida Fakurazi, Pike-See Cheah, Pike-See Cheah, Pike-See Cheah, King-Hwa Ling, King-Hwa Ling, King-Hwa Ling   +7 more
doaj   +1 more source