Results 171 to 180 of about 461,223 (386)

Indoxyl Sulfate Induces Apoptosis through Oxidative Stress and Mitogen-Activated Protein Kinase Signaling Pathway Inhibition in Human Astrocytes [PDF]

, 2019
Yi‐Ting Lin, Ping‐Hsun Wu, Yi‐Chun Tsai, Ya‐Ling Hsu, Han Ying Wang, Mei‐Chuan Kuo, Po‐Lin Kuo, Shang‐Jyh Hwang   +7 more
openalex   +1 more source

Astrocyte GluN2C NMDA receptors control basal synaptic strengths of hippocampal CA1 pyramidal neurons in the stratum radiatum

, 2021
Peter H. Chipman, Chi Chung Alan Fung, Alejandra Pazo Fernández, Abhilash Sawant, A Tedoldi, Atsushi Kawai, Sunita Ghimire Gautam, Mizuki Kurosawa, Manabu Abe, Kenji Sakimura, Tomoki Fukai, Yukiko Goda   +11 more
openalex   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

Advanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton, Chris R. Bowen, Hamideh Khanbareh   +2 more
wiley   +1 more source

Activating the Astrocytes of the Dorsal Raphe Nucleus via Its Neural Circuits With the Medial Prefrontal Cortex Improves Depression in Mice

Behavioural Neurology
Astrocytes are the primary cell type in the central nervous system, responsible for maintaining the stability of the brain’s internal environment and supporting neuronal functions.
Jingyu Zhao, Yuang Wang, Chunxiao Tian, Jialiang Wang, Feng Chen, Xi Dong, Jiayi Luo, Yuxuan Zhu, Aili Liu, Zengguang Ma, Hui Shen   +10 more
doaj   +1 more source

Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain

Cell, 1999
Fiona Doetsch, I. Caillé, D. Lim, J. García-Verdugo, A. Álvarez-Buylla   +4 more
semanticscholar   +1 more source

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

Advanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

FGF-2 Induces Neuronal Death through Upregulation of System xc- [PDF]

, 2014
The cystine/glutamate antiporter (system xc-) transports cystine into cell in exchange for glutamate. Fibroblast growth factor-2 (FGF-2) upregulates system xc- selectively on astrocytes, which leads to increased cystine uptake, the substrate for ...
Albano, Rebecca, Liu, Xiaoqian, Lobner, Doug   +2 more
core   +1 more source

Ptbp1 knockdown failed to induce astrocytes to neurons in vivo [PDF]

, 2022
Guixiang Yang, Zixiang Yan, Xiaoqing Wu, Meng Zhang, Chunlong Xu, Linyu Shi, Hui Yang, Kailun Fang   +7 more
openalex   +1 more source

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

Advanced Science, EarlyView.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang, Tsering Yangzom, Ning Lu, Shenglong Deng, Xianglu Xiao, Guang Yang, Kristina Xiao Liang   +6 more
wiley   +1 more source

Gastrodin regulates expression of angiotensin-SirT3 and proinflammatory mediators in reactive astrocytes via activated microglia [PDF]

, 2022
Hanjun Zuo, Xue‐Qi Ren, Kun Guo, Pengxiang Wang, Min Zhao, Juanjuan Li   +5 more
openalex   +1 more source