Results 171 to 180 of about 303,608 (351)
Advanced Science, EarlyView.PAD1 is upregulated within the CD133+ subset or cisplatin‐resistant ovarian cancer cells, which is positively associated with the upregulation of stemness‐related markers and maintenance of stemness in OCSLCs. Mechanistically, PAD1‐catalyzed AKT2 citrullination at R202 facilitates AKT2 phosphorylation, promoting CEBPβ expression and its binding to the ...
Teng Xue +10 more
wiley +1 more source
Excitatory amino acid-stimulated uptake of 22Na+ in primary astrocyte cultures [PDF]
, 1989 HK Kimelberg, K. Sandy Pang, DH Treble
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The Role of Astrocytes in CNS Inflammation.
Trends in immunology, 2020 Federico Giovannoni, F. Quintana
semanticscholar +1 more source
Advanced Science, EarlyView.24p3R is an astrocytic receptor for α‐Syn uptake. When LCN2 is secreted from astrocytes, it binds to its receptor 24p3R in astrocytes and this binding impedes the α‐Syn PFF binding to 24p3R. This in turn inhibits 24p3R‐mediated α‐Syn PFF uptake and reduces the clearance of extracellular α‐Syn by astrocytes, which contributes to α‐Syn spread and ...
Ying‐Ying Jiao +14 more
wiley +1 more source
HISTOPATHOLOGICAL STUDY ON ASTROCYTE IN VARIOUS LIVER DISEASES PART I
, 1979 Hideki Kida, Shigemi Anraku
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Advanced Science, EarlyView.This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen +12 more
wiley +1 more source
Weak and Tunable Adhesion–Clutch Drives Rapid Cell Migration and Glioblastoma Invasion
Advanced Science, EarlyView.This study proposes that adhesion–clutch can mediate both cell motility and immobilization depending on the force amplitude. Weak adhesion–clutch is well‐suited for cell migration, without forming strong adhesions that impede cell motility. It propels rapid dendritic cell migration controlled by extracellular chemicals, as well as pathologically ...
Kentarou Baba +15 more
wiley +1 more source
Laminin is induced in astrocytes of adult brain by injury.
, 1984 P. Liesi +3 more
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Astrocytes and Microglia: In Sickness and in Health
Trends in Neurosciences, 2020 I. Vainchtein, A. Molofsky
semanticscholar +1 more source
Advanced Science, EarlyView.HOP, an innovative ICT‐based fluorescent probe, visualizes H2O2 in stressed neurons while locally releasing serotonin (5‐HT) for real‐time protein interaction mapping. Its unique tandem sensing and labeling strategy reveals 5‐HT's role under oxidative stress, offering a powerful tool for neurophysiological research and therapeutic discovery.
Yani Liu +9 more
wiley +1 more source