Results 211 to 220 of about 123,114 (319)

TGIF1 overexpression promotes glioma progression and worsens patient prognosis

open access: yesCancer Medicine, Volume 11, Issue 24, Page 5113-5128, December 2022., 2022
This study is the first to comprehensively analyze and reveal TGIF1, as a new oncogene, is closely related to the malignancy‐related phenotype of glioma, and that TGIF1 could be an independent risk factor for poor prognosis of glioma, which is expected to become a new target for individualized treatment of glioma patients.
Baoya Wang   +5 more
wiley   +1 more source

Artificial Intelligent‐Enhanced Metabolite Profiling for Intraoperative IDH1 Genotyping in Glioma Using an Orthogonally Responsive SERS Probe

open access: yesAdvanced Science, EarlyView.
This study presents a novel approach for intraoperative identification of the IDH1 genotype in glioma patients using a surface‐enhanced Raman scattering (SERS) probe to measure glutathione and hydrogen peroxide. By integrating AI‐driven deep learning algorithms, the method achieves rapid and accurate genotype differentiation, offering the potential to ...
Hang Yin   +14 more
wiley   +1 more source

Exosomes and their roles in the chemoresistance of pancreatic cancer

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4979-4988, December 2022., 2022
Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan   +4 more
wiley   +1 more source

HDL‐Apolipoprotein in Alzheimer's Disease Revisited: From Periphery to CNS

open access: yesAGING MEDICINE, EarlyView.
HDL‐apolipoproteins in the periphery and CNS contribute differently to Alzheimer's disease, influencing Aβ, p‐tau, brain structures, and cognition. Apolipoprotein AI and E, key HDL components in blood and CSF, may either protect against or accelerate AD, depending on their location. Created with BioGDP.com. ABSTRACT High‐density lipoprotein (HDL), as a
Yihong Huang   +8 more
wiley   +1 more source

Spinal astrocyte-derived interleukin-17A promotes pain hypersensitivity in bone cancer mice

open access: yesActa Pharmaceutica Sinica B
Spinal microglia and astrocytes are both involved in neuropathic and inflammatory pain, which may display sexual dimorphism. Here, we demonstrate that the sustained activation of spinal astrocytes and astrocyte-derived interleukin (IL)-17A promotes the ...
Huizhu Liu   +6 more
doaj  

Laminin is induced in astrocytes of adult brain by injury.

open access: bronze, 1984
P. Liesi   +3 more
openalex   +1 more source

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