Results 211 to 220 of about 461,223 (386)

LRP4+ Astrocytes: A Unique Subpopulation Crucial for Blood Vessel Maintenance and Function in the Somatosensory Cortex of Normal and 5xFAD Mice. [PDF]

Glia
Arzola E, Yu G, Xiong L, Lee D, Wu A, Paruchuri S, Skinner J, Wang M, Zhang B, Mei L, Xiong WC.   +10 more
europepmc   +1 more source

Ultrastructural view of astrocyte-astrocyte and astrocyte-synapse contacts within the hippocampus [PDF]

, 2020
Conrad M. Kiyoshi, Sydney Aten, Emily P. Arzola, Jeremy Patterson, Anne Taylor, Yixing Du, Ally M. Guiher, Merna Philip, Elizabeth Gerviacio Camacho, Devin Mediratta, Kelsey A. Collins, Emily Benson, Grahame J. Kidd, David Terman, Min Zhou   +14 more
openalex   +1 more source

Advanced Stem Cell Therapy: 3D‐Bioprinted Brain‐Like Transplants for Alzheimer's Disease‐Like Dementia

Advanced Science, EarlyView.
A tri‐component biomimetic bioink(gelatin/alginate/fibrinogen) is developed to protect cells in critical pathological environments in AD. Using this bioink, a 3D‐printed NPC construct optimized for hippocampal transplantation is provided to improve cell retention and differentiation in an AD‐like model. This approach enhances memory recovery and offers
Ke Gai, Yu Song, Dawen Gao, Qingning Nie, Xiao Luo, Caizhe Xu, Changhao Cai, Austin Smith, Xiang Li, Wei Shi, Lei Zhang, Wei Sun, Feng Lin   +12 more
wiley   +1 more source

Altered Mechanical Properties of Astrocytes Lacking MLC1: Implications for the Leukodystrophy MLC. [PDF]

Glia
Bisseling Q, Passchier EMJ, Kirwan FM, Antonovaite N, Camerini S, Brignone MS, Freal A, Mansvelder HD, Ambrosini E, van der Knaap MS, Min R.   +10 more
europepmc   +1 more source

ATPIF1 alleviates oxygen glucose deprivation/reoxygenation-induced astrocyte injury in vitro – a rat model of ischemic brain injury

, 2022
Zhijie Wei, Rui Wu, Li Zhang, Ping Xu
openalex   +2 more sources

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source

Astrocytic TCF7L2 Impacts Brain Osmoregulation and Restricts Neuronal Excitability. [PDF]

Glia
Popek M, Goryca K, Adamska D, Urban-Ciećko J, Hryniewiecka K, Lipiec M, Krawczyk TG, Rafalko K, Ławicka A, Liddelow SA, Szewczyk LM.   +10 more
europepmc   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Novel Roles for the Ectoenzyme CD38 in the Maintenance of Transcriptional and Metabolic Homeostasis in Astrocytes. [PDF]

Glia
Basak S, Colafrancesco AM, Hernandez RD, Wei X, McMeekin LJ, Dang D, Simmons M, Browning JL, Noel K, Zhou F, Lund FE, Saad JS, Watsen SG, Pickrell AM, Cowell RM, Olsen ML.   +15 more
europepmc   +1 more source

Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes

, 2016
Ana González-Sánchez, Myriam Jaraíz-Rodríguez, Marta Domínguez-Prieto, Sandra Herrero‐González, José M. Medina, Arantxa Tabernero   +5 more
openalex   +2 more sources