Reactive Astrocytes Release GDNF to Promote Brain Recovery and Neuronal Survival Following Ischemic Stroke. [PDF]
Zhang Z, Zhang N, Ding S.
europepmc +1 more source
Serotonergic modulators in Alzheimer's disease: a hope in the hopeless condition
Alzheimer disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Ali I. Al-Gareeb+5 more
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Body weight-supported treadmill training reduces glial scar overgrowth in SCI rats by decreasing the reactivity of astrocytes during the subacute phase. [PDF]
Cai J+10 more
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The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its promising ...
Dayanna Isabel Araque Gelves+3 more
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Role of phospholipase Cη1 in lateral habenula astrocytes in depressive-like behavior in mice. [PDF]
Song S+11 more
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Insulin and Metformin are Associated With Reduced Risk of Amyotrophic Lateral Sclerosis
Human insulin heterodimer (A). Human insulin heterodimer (dark blue) docked within center of Cx43 channel (B) Abstract Background Type 2 diabetes (T2D), but not type 1, protected against amyotrophic lateral sclerosis (ALS). In T2D serum insulin is normal or elevated in the early stages.
Steven Lehrer, Peter H. Rheinstein
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The impact of exogenous Oxytocin on visual cortex plasticity across different stages of visual development. [PDF]
Sun Y, Wang X, Chen Y, Luan Z, Hao R.
europepmc +1 more source
Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele
Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin+5 more
wiley +1 more source
Elucidating the Role of Trem2 in Lipid Metabolism and Neuroinflammation. [PDF]
Zhao C+5 more
europepmc +1 more source