Results 341 to 350 of about 440,890 (382)

The Potential Role of Exosomes in Communication Between Astrocytes and Endothelial Cells. [PDF]

Int J Mol Sci
Czpakowska J, Głąbiński A, Szpakowski P.   +2 more
europepmc   +1 more source

Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele

Chronic Diseases and Translational Medicine, EarlyView.
Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin, Farizky Martriano Humardani, Fenny Lanawati Yudiarto, Paulus Anam Ong, Sulistyo Emantoko Dwi Putra, Ratih Asmana Ningrum   +5 more
wiley   +1 more source

MitoTracker transfers from astrocytes to neurons independently of mitochondria

Hole KL, Norkett R, Russell E, Strom M, Howden JH, Corbett NJ, Brownlees J, Devine MJ.   +7 more
europepmc   +1 more source

Ubiquitination-mediated upregulation of glycolytic enzyme MCT4 in promoting astrocyte reactivity during neuroinflammation. [PDF]

J Neuroinflammation
Yang L, Hu C, Chen X, Sun M, Zhang J, Feng Z, Cui T, Zhu R, Zhang X, Xiao Y, Gong Y, Yang Y, Zhang Q, Zhang Y, Yan Y.   +14 more
europepmc   +1 more source

Development of CPA‐Catalyzed β‐Selective Reductive Amination of Cardenolides for the Synthesis and Biological Evaluation of Hydrolytically Stable Analogs

Chemistry – A European Journal, EarlyView.
We describe a new method to produce hydrolytically stable cardiotonic steroids using a CPA‐controlled diastereoselective reductive amination of cardenolide aglycones. The oleandrin and digitoxigenin analogs exhibited promising activity against various cancer cell lines in the NCI‐60 screen.
Natasha Perry, Shehab Eid, Gerold Schmitt‐Ulms, Pavel Nagorny   +3 more
wiley   +1 more source

Hes5⁺ astrocytes potentiate primary afferent Aδ and C fiber-mediated excitatory synaptic transmission to spinal lamina I neurons. [PDF]

Mol Brain
Kagiyama I, Uchiyama S, Tsuda M.
europepmc   +1 more source

Manganese Neurotoxicity and Familial Disorders of Manganese Transport

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley   +1 more source

Lysosomal stress induces amyloid-β aggregate release and reactive transformation in human astrocytes

Goldsworthy S, Fertan E, Dyal P, Domoney S, Livesey FJ, Klenerman D, Patani R, Hung C.   +7 more
europepmc   +1 more source

Astrocytes Lingering at a Crossroads: Neuroprotection and Neurodegeneration in Neurocognitive Dysfunction. [PDF]

Int J Biol Sci
Xu X, Mei B, Yang Y, Li J, Weng J, Yang Y, Zhu Q, Zhang H, Liu X.   +8 more
europepmc   +1 more source

A head start: The relationship of placental factors to craniofacial and brain development

Developmental Dynamics, EarlyView.
Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver, Martine Dunnwald, Hanna Elizabeth Stevens   +2 more
wiley   +1 more source