Results 141 to 150 of about 11,776 (162)
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Morphological plasticity of rodent astroglia
Journal of Neurochemistry, 2012AbstractIn the past two decades, there has been an explosion of research on the role of neuroglial interactions in the control of brain homeostasis in both physiological and pathological conditions. Astrocytes, a subtype of glia in the central nervous system, are dynamic signaling elements that regulate neurogenesis and development of brain circuits ...
Richard Burnard, Rodnight +1 more
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Alcohol, astroglia, and brain development
Molecular Neurobiology, 1997Glial cells constitute one of the most common cell types in the brain. They play critical roles in central nervous system (CNS) development. Recent evidence demonstrates that glial cells are profoundly affected by prenatal alcohol exposure, suggesting that alterations in these cells may participate in CNS abnormalities associated with ethanol-induced ...
C, Guerri, J, Renau-Piqueras
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Astroglia in Alzheimer's disease
Neurobiology of Aging, 1992Amyloid deposits are characteristic of Alzheimer's Disease (AD) and there is growing evidence that amyloid may play an important role in the genesis of this neurodegenerative disease. This review discusses data which suggests that reactive astrocytes and microglia may be a necessary concomitant with amyloid to produce the neuropathology which manifests
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Astroglia and Obsessive Compulsive Disorder
2021Obsessive compulsive disorder (OCD) has a prevalence rate of 1-3% in the general population and has been ranked as one of the top ten leading causes of illness-related disability (American Psychiatric Association 2013; Kessler et al. 2005). OCD is characterized by persistent intrusive thoughts (obsessions) and repetitive behaviors (compulsions ...
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Embryonic cerebellar astroglia in vitro
Developmental Brain Research, 1984Three types of astroglia appear during cerebellar development--radial glia and Bergmann glia, which are thought to facilitate neuronal migration, and astrocytes, which are thought to compartmentalize mature granule neurons. Cells resembling Bergmann glia and astrocytes have been described in cultures of cerebellar cells harvested from early postnatal ...
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Immunohistochemical study of human retinal astroglia
Vision Research, 1994Immunocytochemical localization of glial fibrillary acidic protein (GFAP) has been used to study astrocyte distribution and morphology in whole mounted human retinas and vertical sections. Two types of astrocytes can be distinguished: elongated astrocytes are located in the nerve fibre layer (NFL); and star-shaped astrocytes are found in the ganglion ...
J M, Ramirez +4 more
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Retinal perivascular astroglia: an immunoperoxidase study
Vision Research, 1992Different morphological types of retinal perivascular astrocytes have been studied in wholemount preparations of rabbit retina. Astrocytes were immunohistochemically demonstrated using glial fibrillary acidic protein monoclonal antibodies (GFAP clone GA-5). Three types of perivascular astrocytes were found.
A, Triviño +4 more
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Purinergic and Glutamatergic Receptors on Astroglia
2014Astroglial cells express many neurotransmitter receptors; the receptors to glutamate and ATP being the most abundant. Here, we provide a concise overview on the expression and main properties of astroglial glutamate receptors (ionotropic receptors represented by AMPA and NMDA subtypes) and metabotropic (mainly mGluR5 and mGluR3 subtypes) and ...
Verkhratsky, A, Burnstock, G
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Astroglia, Glutamatergic Transmission and Psychiatric Diseases
2016Astrocytes are primary homeostatic cells of the central nervous system. They regulate glutamatergic transmission through the removal of glutamate from the extracellular space and by supplying neurons with glutamine. Glutamatergic transmission is generally believed to be significantly impaired in the contexts of all major neuropsychiatric diseases.
Verkhratsky, Alexei +3 more
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2004
Glutamate is the predominant excitatory neurotransmitter in the central nervous system (CNS), and as a result is continually secreted from cells. It is essential that vesicular release result in fluctuations in the concentration of glutamate that are spatially and temporally constrained, to restrict signaling to defined contacts and to allow signaling ...
Dwight E. Bergles, Jeffrey D. Rothstein
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Glutamate is the predominant excitatory neurotransmitter in the central nervous system (CNS), and as a result is continually secreted from cells. It is essential that vesicular release result in fluctuations in the concentration of glutamate that are spatially and temporally constrained, to restrict signaling to defined contacts and to allow signaling ...
Dwight E. Bergles, Jeffrey D. Rothstein
openaire +1 more source