Results 21 to 30 of about 11,776 (162)

Long-Lasting Pathological Mental Fatigue After Brain Injury–A Dysfunction in Glutamate Neurotransmission?

Frontiers in Behavioral Neuroscience, 2022
Long-lasting mental or cognitive fatigue may be a disabling symptom after physically recovered skull trauma, stroke, infection, or inflammation in the central nervous system (CNS).
Lars Rönnbäck, Birgitta Johansson
doaj   +1 more source

GABA, but Not Bestrophin-1, Is Localized in Astroglial Processes in the Mouse Hippocampus and the Cerebellum

Frontiers in Molecular Neuroscience, 2020
GABA is proposed to act as a gliotransmitter in the brain. Differences in GABA release from astroglia are thought to underlie differences in tonic inhibition between the cerebellum and the CA1 hippocampus.
Lasse Ormel, Lasse Ormel, Knut H. Lauritzen, Knut H. Lauritzen, Rainer Schreiber, Karl Kunzelmann, Vidar Gundersen, Vidar Gundersen   +7 more
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Modest Reduction in CAG Repeat Length Rescues Motor Deficits but Not Purkinje Cell Pathology and Gliosis in Spinocerebellar Ataxia Type 1 Mice

Neuroglia, 2023
Spinocerebellar ataxia type 1 (SCA1) is a fatal, dominantly inherited neurodegenerative disease caused by the expansion of CAG repeats in the Ataxin-1 (ATXN1) gene.
Stephen Gilliat, Juao-Guilherme Rosa, Genevieve Benjamin, Kaelin Sbrocco, Wensheng Lin, Marija Cvetanovic   +5 more
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Directing astroglia from the cerebral cortex into subtype specific functional neurons.

PLoS Biology, 2010
Astroglia from the postnatal cerebral cortex can be reprogrammed in vitro to generate neurons following forced expression of neurogenic transcription factors, thus opening new avenues towards a potential use of endogenous astroglia for brain repair ...
Christophe Heinrich, Robert Blum, Sergio Gascón, Giacomo Masserdotti, Pratibha Tripathi, Rodrigo Sánchez, Steffen Tiedt, Timm Schroeder, Magdalena Götz, Benedikt Berninger   +9 more
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Astroglia in Sepsis Associated Encephalopathy [PDF]

Neurochemical Research, 2019
Cellular pathophysiology of sepsis associated encephalopathy (SAE) remains poorly characterised. Brain pathology in SAE, which is manifested by impaired perception, consciousness and cognition, results from multifactorial events, including high levels of systemic cytokines, microbial components and endotoxins, which all damage the brain barriers ...
Tatyana Shulyatnikova, Alexei Verkhratsky   +1 more
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Relation between the Severity of the Sensorimotor Cortical Edema with Cell Swelling and the Duration of Common Carotid Artery Occlusion in Rats (Morphometric Study)

Общая реаниматология, 2021
The aim of the study. To examine the changes in structure and morphometry in sensorimotor cortical edema with cell swelling in mature white rats after common carotid artery occlusion of various durations.Material and methods.
S. S. Stepanov, D. V. Avdeev, V. A. Akulinin, A. Yu. Shoronova, L. M. Makarieva, M. S. Korzhuk   +5 more
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Influence of occlusal interferences on the activation of trigeminal-spinal nucleus astroglia and microglia in rats

口腔疾病防治, 2016
Objective To investigate the morphological changes in microglia and astroglia before and after the removal of occlusal interferences in rats and to further understand whether astroglia and microglia activation is involved in experimental occlusal ...
LIU Cunrui, CAO Ye, XU Xiaoxiang, XIE Qiufei   +3 more
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Synaptamide Modulates Astroglial Activity in Mild Traumatic Brain Injury

Marine Drugs, 2022
At present, the study of the neurotropic activity of polyunsaturated fatty acid ethanolamides (N-acylethanolamines) is becoming increasingly important.
Arina Ponomarenko, Anna Tyrtyshnaia, Darya Ivashkevich, Ekaterina Ermolenko, Inessa Dyuizen, Igor Manzhulo   +5 more
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Pathological potential of astroglia

Physiological Research, 2008
The pathological potential of glial cells was recognized already by Rudolf Virchow, Santiago Ramon y Cajal and Pio Del Rio-Ortega. Many functions and roles performed by astroglia in the healthy brain determine their involvement in brain diseases; as indeed any kind of brain insult does affect astrocytes, and their performance in pathological conditions,
Chvátal, A., Anděrová, M., Neprašová, Helena, Prajerová, Iva, Benešová, Jana, Butenko, O., Verkhratsky, A.   +6 more
openaire   +3 more sources

Brain region-specificity of palmitic acid-induced abnormalities associated with Alzheimer's disease

BMC Research Notes, 2008
Background Alzheimer's disease (AD) is a progressive, neurodegenerative disease mostly affecting the basal forebrain, cortex and hippocampus whereas the cerebellum is relatively spared.
Melrose Joseph, Balu Deebika, Patil Sachin, Chan Christina   +3 more
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