Results 81 to 90 of about 11,776 (162)

Astrocyte Bioenergetic Remodeling as a Central Trait of Disrupted Glucocorticoid Signaling: Mechanisms and Implications for Stress Vulnerability

Journal of Neurochemistry, Volume 170, Issue 3, March 2026.
Low/brief glucocorticoid (GC) elevations can enhance mitochondrial output (↑ oxygen consumption rate, OCR; ↑ mitochondrial membrane potential, ΔΨm) and Ca2+ buffering, in part via glucocorticoid receptor (GR) trafficking to mitochondria in complexes with Bcl2 and Bag1.
Paweł Hanus, Dorota Frydecka, Michał Ślęzak   +2 more
wiley   +1 more source

NRXN1 Deletion and Exposure to Methylmercury Increase Astrocyte Differentiation by Different Notch-Dependent Transcriptional Mechanisms

Frontiers in Genetics, 2019
Controversial evidence points to a possible involvement of methylmercury (MeHg) in the etiopathogenesis of autism spectrum disorders (ASD). In the present study, we used human neuroepithelial stem cells from healthy donors and from an autistic patient ...
Marilena Raciti, Jahan Salma, Stefan Spulber, Giulia Gaudenzi, Zahra Khalajzeyqami, Mirko Conti, Britt-Marie Anderlid, Britt-Marie Anderlid, Anna Falk, Ola Hermanson, Sandra Ceccatelli   +10 more
doaj   +1 more source

Pathobiology of Neurodegeneration: The Role for Astroglia

Opera medica et physiologica, 2016
The common denominator of neurodegenerative diseases, which mainly affect humans, is the progressive death of neural cells resulting in neurological and cognitive deficits. Astroglial cells are the central elements of the homoeostasis, defence and regeneration of the central nervous system, and their malfunction or reactivity contribute to the ...
Verkhratsky, Alexei, Zorec, Robert, Rodriguez, Jose J, Parpura, Vladimir   +3 more
openaire   +4 more sources

Changes of Microglial Cells in the Progression of Neurodegeneration in Natural Prion Disease

Frontiers in Bioscience-Landmark
Background: In recent years, neuroglia has become a therapeutic target for neurodegenerative diseases. Despite the recognition of a variety of microglial morphologies associated with the neuroinflammatory process that involve diverse ...
Marta Monzón, Juan Sauca Pérez, Rodrigo S. Hernández, Rocío Sarasa, Moisés Garcés, M José Luesma, Juan J Badiola   +6 more
doaj   +1 more source

Copper Metabolism of Astrocytes

Frontiers in Aging Neuroscience, 2013
This short review will summarize the current knowledge on the uptake, storage and export of copper ions by astrocytes and will address the potential roles of astrocytes in copper homeostasis in the normal and diseased brain.
Ralf eDringen, Ivo F Scheiber, Julian FB Mercer   +2 more
doaj   +1 more source

Astroglia: Not Just Glue [PDF]

Journal of Neuropsychiatry, 2008
Katherine H, Taber, Robin A, Hurley
openaire   +2 more sources

Apolipoprotein E dysfunction in Alzheimer’s disease: a study on miRNA regulation, glial markers, and amyloid pathology

Frontiers in Aging Neuroscience
IntroductionApolipoprotein E (ApoE) plays a crucial role in lipid homeostasis, predominantly expressed in astrocytes and to a lesser extent in microglia within the central nervous system (CNS).
Printha Wijesinghe, Hao Ran Li, Zhengyuan Ai, Matthew Campbell, Si Xuan Chen, Jeanne Xi, Wellington Pham, Wellington Pham, Joanne A. Matsubara, Joanne A. Matsubara   +9 more
doaj   +1 more source

Editorial: Modulating Glial Cells Phenotype: New Findings and Therapies

Frontiers in Aging Neuroscience, 2020
María José Bellini, Yolanda Diz-Chaves, Alberto Javier Ramos   +2 more
doaj   +1 more source

An ultrastructural map of a spinal sensorimotor circuit reveals the potential of astroglia modulation. [PDF]

Cell Rep
Koh ZM, Arceo RA, Hammer J, Chau K, Light SEW, Dolojan A, Januszewski M, Svara F, Smith CJ.   +8 more
europepmc   +1 more source

Glial-neuronal ensembles: partners in drug addiction-associated synaptic plasticity

Frontiers in Pharmacology, 2014
Jean Lud eCadet, Veronica eBisagno
doaj   +1 more source