Results 31 to 40 of about 2,602 (175)

Efficacy and safety of daclatasvir plus asunaprevir for Korean patients with HCV genotype Ib infection: a retrospective multi-institutional study [PDF]

open access: yesClinical and Molecular Hepatology, 2017
Background/Aims The combination of daclatasvir (DCV) and asunaprevir (ASV) has demonstrated a high sustained virologic response at 12 weeks (SVR12) and a low rate of adverse events in previous clinical studies.
Byeong Wook Cho   +9 more
doaj   +1 more source

Case report of successful peginterferon, ribavirin, and daclatasvir therapy for recurrent cholestatic hepatitis C after liver retransplantation [PDF]

open access: yes, 2012
A recurrent hepatitis C virus (HCV) infection after liver transplantation (LT) can lead to accelerated allograft injury and fibrosis. The aim of this article is to report the first ever use of daclatasvir (DCV; also known as BMS‐790052), a potent orally ...
Alcaide   +41 more
core   +1 more source

Predictors of the efficiency of short-term interferon-containing therapy using direct-acting antiviral drugs in patients with chronic hepatitis C virus genotype 1

open access: yesТерапевтический архив, 2017
Aim. To identify predictors for the high efficiency of short-term interferon-containing antiviral therapy (AVT) using direct-acting antivirals (DAAs) in patients with chronic hepatitis C (CHC) virus (HCV) type 1 (CHC-1). Materials and methods. A total of
K Yu Kokina   +3 more
doaj   +1 more source

Evaluation of the effi cacy and safety of the use of asunaprevir in combination with daclatasvir in patients with chronic hepatitis С: a prospective cohort study

open access: yesМедицинский вестник Юга России, 2017
Objective: to give assessment of the effi cacy and safety of using asunaprevir in combination with daclatasvir in patients with chronic hepatitis C (HCV) with severe fi brosis and cirrhosis.
Elena B. Romanova   +5 more
doaj   +1 more source

HCV-1b intra-subtype variability: Impact on genetic barrier to protease inhibitors [PDF]

open access: yes, 2014
Due to error-prone RNA polymerase and the lack of proofreading mechanisms, to the spread worldwide and probable long-term presence in human population, HCV showed a high degree of inter- and intra-subtype genetic variability. Protease inhibitors (PIs), a
CRAXI, Antonio   +3 more
core   +1 more source

Structure-activity relationships of fluorene compounds inhibiting HCV variants [PDF]

open access: yes, 2020
Approximately 71 million people suffer from hepatitis C virus (HCV) infection worldwide. Persistent HCV infection causes liver diseases such as chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma, resulting in approximately 400,000 deaths ...
Gadhe, Changdev G.   +10 more
core   +1 more source

Efficacy of daclatasvir and asunaprevir for viral hepatitis С in two donor lung recipients

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim. To estimate efficacy and safety of direct antiviral drugs for hepatitis C treatment in donor lung recipients. Key points. The first cases in Russian literature and one of the first-ever cases of hepatitis C treatment by direct antiviral agents in ...
D. T. Abdurakhmanov   +4 more
doaj   +1 more source

Eradication of hepatitits C virus in patient with cryoglobulinemic vasculitis and mutations D168E, L31V

open access: yesЖурнал инфектологии, 2020
The case of chronic hepatitis C 1b genotype with grade 3 fibrosis according to Metavir, complicated by the development  of mixed  type  III  cryoglobulinemia,  cryoglobulinemic vasculitis with damage to the skin vessels of the skin (hemorrhagic ...
N. V. Dunaeva   +6 more
doaj   +1 more source

Outcomes for Cirrhotic Patients with Hepatitis C Virus 1b Treated with Asunaprevir and Daclatasvir Combination

open access: yesAnnals of Hepatology, 2017
Background: The efficacy and safety of asunaprevir + daclatasvir combination therapy for treatment of hepatitis C virus (HCV) in compensated cirrhotic patients was not fully evaluated in real-world.
Akihiro Tamori   +12 more
doaj   +1 more source

CD4+T cells and natural killer cells: Biomarkers for hepatic fibrosis in human immunodeficiency virus/hepatitis C viruscoinfected patients [PDF]

open access: yes, 2017
To characterize peripheral blood natural killer (NK) cells phenotypes by flow cytometry as potential biomarker of liver fibrosis in human immunodeficiency virus (HIV)/hepatitis C virus (HCV) coinfected patients.
Cahn, Pedro   +8 more
core   +1 more source

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