Results 1 to 10 of about 263,661 (293)

Diagnosis of hepatitis C virus genotype 2k/1b needs NS5B sequencing [PDF]

International Journal of Infectious Diseases, 2015
Hepatitis C virus (HCV) is probably the most common cause of liver cirrhosis and hepatocellular carcinoma worldwide. The correct identification of HCV genotype has important clinical implications as a marker of responsiveness to antiviral therapy and ...
Steven De Keukeleire, Patrick Descheemaeker, Marijke Reynders   +2 more
doaj   +4 more sources

NS4A protein as a marker of HCV history suggests that different HCV genotypes originally evolved from genotype 1b [PDF]

Virology Journal, 2011
Background The 9.6 kb long RNA genome of Hepatitis C virus (HCV) is under the control of RNA dependent RNA polymerase, an error-prone enzyme, for its transcription and replication.
Asad Sultan, Ashfaq Usman A, Sumrin Aleena, Ansar Muhammad, Ahmad Waqar, Ijaz Bushra, Kausar Humera, Sarwar Muhammad T, Gull Sana, Shahid Imran, Hassan Sajida   +10 more
doaj   +5 more sources

Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection. [PDF]

Hepatology, 2014
All-oral combinations of direct-acting antivirals may improve efficacy and safety outcomes for patients with hepatitis C virus (HCV) infection, particularly those who are poor candidates for current interferon/ribavirin-based regimens.
Kumada H, Suzuki Y, Ikeda K, Toyota J, Karino Y, Chayama K, Kawakami Y, Ido A, Yamamoto K, Takaguchi K, Izumi N, Koike K, Takehara T, Kawada N, Sata M, Miyagoshi H, Eley T, McPhee F, Damokosh A, Ishikawa H, Hughes E.   +20 more
europepmc   +4 more sources

Daclatasvir and asunaprevir combination therapy for patients with chronic hepatitis C virus genotype 1b infection in real world [PDF]

The Korean Journal of Internal Medicine, 2019
Background/Aims Previous studies have reported a high rate of sustained virologic response (SVR) and a low rate of serious adverse events with the use of daclatasvir (DCV) and asunaprevir (ASV) combination therapy. We evaluated the efficacy and safety of
Jae Young Oh, Byung Seok Kim, Chang Hyeong Lee, Jeong Eun Song, Heon Ju Lee, Jung Gil Park, Jae Seok Hwang, Woo Jin Chung, Byoung Kuk Jang, Young Oh Kweon, Won Young Tak, Soo Young Park, Se Young Jang, Jeong Ill Suh, Sang Gyu Kwak   +14 more
doaj   +2 more sources

Efficacy and safety of daclatasvir and asunaprevir for hepatitis C virus genotype 1b infection. [PDF]

Clin Mol Hepatol, 2016
The treatment strategy for hepatitis C virus (HCV) has been changing rapidly since the introduction of direct-acting antivirals such as daclatasvir (DCV) and asunaprevir (ASV). We evaluated the efficacy and safety of DCV and ASV for HCV in real-life practice.Patients were treated with 60 mg of DCV once daily plus 200 mg of ASV twice daily for 24 weeks,
Nam HC, Lee HL, Yang H, Song MJ.
europepmc   +5 more sources

A Unique Genotype of Pseudohypoaldosteronism Type 1b in a Highly Consanguineous Population [PDF]

Journal of the Endocrine Society, 2021
Abstract Context Pseudohypoaldosteronism (PHA) is a condition in which serum aldosterone level is normal or elevated but its action is deficient. Objective This study describes the molecular genetics of PHA 1b in the highly ...
Ali S Alzahrani, Meshael Alswailem, Bassam Bin Abbas, Ebtesam Qasem, Afaf Alsagheir, Azza Al Shidhani, Aisha Al Sinani, Maryam Al Badi, Ali Al-Maqbali, Manal Al Shawi, Abdulhameed Albunyan, Abdulghani Bin Nafisah, Yufei Shi   +12 more
openaire   +2 more sources

Distribution of Hepatitis C Virus Genotypes in Patients Diagnosed with Hepatitis C in Our Hospital: 2015-2018

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2021
Introduction: This study aimed to investigate the distribution of hepatitis C virus (HCV) genotype and its variability in certain sociodemographics in patients with chronic hepatitis.
Demet HACISEYİTOĞLU, Rabia CAN SARINOĞLU, Ayşegül GÖZALAN, Ayşe BATIREL, Güner SÖYLETİR   +4 more
doaj   +1 more source

Molecular Characterization of Novel x-Type HMW Glutenin Subunit 1B × 6.5 in Wheat

Plants, 2021
A novel high molecular weight glutenin subunit encoded by the Glu-1B locus was identified in the French genotype Bagou, which we named 1B × 6.5. This subunit differed in SDS-PAGE from well-known 1B × 6 and 1B × 7 subunits, which are also encoded at this ...
Tímea Kuťka Hlozáková, Zdenka Gálová, Svetlana Šliková, Leona Leišová-Svobodová, Jana Beinhauer, Filip Dyčka, Marek Šebela, Erika Zetochová, Edita Gregová   +8 more
doaj   +1 more source

Development of a Method for Screening and Genotyping of HCV 1a, 1b, 2, 3, 4, and 6 Genotypes [PDF]

ACS Omega, 2020
The World Health Organization and the World Health Assembly recommended eradicating hepatitis as a public threat by 2030. The accurate genotyping of hepatitis C virus (HCV) is crucial to achieving this goal because it is vital for the selection of anti-HCV therapy required for complete cure of HCV infection.
Shrikant Dashrath Warkad, Satish Balasaheb Nimse, Keum-Soo Song, Taisun Kim   +3 more
openaire   +3 more sources

Histopathology of chronic hepatitis C in relation to virus genotype [PDF]

Vojnosanitetski Pregled, 2006
Background/aim: The natural history of hepatitis C virus (HCV) infection is variable and the factors determining the course of the illness are unclear. There are geographical variations in the distribution of different HCV genotypes, and some of them are
Simonović Jasmina, Dokić Ljubiša, Čutović Milisav, Tomanović Nada, Boričić Ivan, Prostran Milica, Nešić Zorica, Delić Dragan, Švirtlih Neda   +8 more
doaj   +1 more source