Efficacy and safety of daclatasvir and asunaprevir for hepatitis C virus genotype 1b infection. [PDF]
Clin Mol Hepatol, 2016 The treatment strategy for hepatitis C virus (HCV) has been changing rapidly since the introduction of direct-acting antivirals such as daclatasvir (DCV) and asunaprevir (ASV). We evaluated the efficacy and safety of DCV and ASV for HCV in real-life practice.Patients were treated with 60 mg of DCV once daily plus 200 mg of ASV twice daily for 24 weeks,
Nam HC, Lee HL, Yang H, Song MJ.
europepmc +5 more sources
Superinfection of Chimpanzees Carrying Hepatitis C Virus of Genotype Ii/1B With That of Genotype Iii/2A or I/1A [PDF]
Hepatology, 1994 Three chimpanzees persistently infected with hepatitis C virus of genotype II/1b were challenged with hepatitis C virus of genotype III/2a and 6 wk later with hepatitis C virus of genotype I/1a.
H, Okamoto +5 more
openaire +2 more sources
Contribution of Cyclin-dependent Kinase Inhibitor 1B Genotypes to Childhood Leukemia Risk
In Vivo, 2022 Although genetic differences in cell-cycle control genes have been associated with cancer risk, to our knowledge, no report has specifically examined the role of gene variants in childhood acute lymphoblastic leukemia (ALL). Cyclin-dependent kinase inhibitor 1B (CDKN1B; also known as p27/KIP1) is a cell-cycle regulating gene.
Jen-Sheng, Pei +10 more
openaire +2 more sources
Association of CYP3A4 and CYP3A5 polymorphisms with Iranian breast cancer patients
Egyptian Journal of Medical Human Genetics, 2015 Background: Polymorphisms of different gene have been reported to be associated with cancer including breast cancer. Hospitalization rate for breast cancer has increased over the years in Iran.
Elham Badavi +5 more
doaj +1 more source
Hepatitis C Virus Genotyping: Interrogation of the 5′ Untranslated Region Cannot Accurately Distinguish Genotypes 1a and 1b [PDF]
Journal of Clinical Microbiology, 2002 ABSTRACT Although the 5′ untranslated region (5′ UTR) is the most conserved region of the hepatitis C virus (HCV) genome, it has been suggested that interrogation of this region is sufficient for determination of the HCV genotype. We compared two methods of determination of the HCV genotype: (i) direct sequencing of the DNA of the NS-5b ...
Zhenyu, Chen, Karen E, Weck
openaire +2 more sources
Prevalence of NS5A Inhibitor Resistance Mutations in Genotype 1b Patients.
, 2016 Prevalence of NS5A Inhibitor Resistance Mutations in Genotype 1b Patients.
Chihong Wu (3331833) +7 more
core +1 more source
Alcohol dehydrogenase 1B genotype and fetal alcohol syndrome: a HuGE minireview
American Journal of Obstetrics and Gynecology, 2007 Fetal alcohol syndrome (FAS), 1 of the most common developmental disabilities in the United States, occurs at a rate of 0.5-2.0:1000 live births. Animal model, family, and twin studies suggest a genetic component to FAS susceptibility. Alcohol dehydrogenases (ADHs) catalyze the rate-limiting step in alcohol metabolism.
Green, Ridgely Fisk +1 more
openaire +2 more sources
Prevalence of NS5B Polymerase Inhibitor Resistance Mutations in Genotype 1b Patients.
, 2016 Prevalence of NS5B Polymerase Inhibitor Resistance Mutations in Genotype 1b Patients.
Chihong Wu (3331833) +7 more
core +1 more source
Prevalence of NS3 Protease Inhibitor Resistance Mutations in Genotype 1b Patients.
, 2016 Prevalence of NS3 Protease Inhibitor Resistance Mutations in Genotype 1b Patients.
Chihong Wu (3331833) +7 more
core +1 more source
Epidemiology and Genotype Distribution of Hepatitis C Virus in Russia
Pathogens, 2022 The hepatitis C virus (HCV) causes both acute and chronic infection of the liver that can lead to liver cirrhosis, cancer, and liver failure. HCV is characterized by high genetic diversity and substantial variations in the prevalence of specific HCV ...
Nikolay Pimenov +9 more
doaj +1 more source