Results 131 to 140 of about 637,304 (300)

Scaffold hopping yields novel furo[3,2-d]pyrimidine NNRTIs with optimized antiviral potency, enhanced selectivity, and reduced hERG liability

Acta Pharmaceutica Sinica B
Considering the exceptional anti-HIV-1 potency of rilpivirine (RPV) against diverse mutant strains and its remarkable human ether-a-go-go related gene (hERG) potassium channel inhibition (IC50 = 0.50 μmol/L) as well as low selectivity (SI = 3989), a ...
Yin-Xiang Zhang, Christophe Pannecouque, Erik De Clercq, Enzo Tramontano, Angela Corona, Laura Dettori, Phuong-Thao Tran, Xu-Dong Li, Shuo Su, Shuai Wang, Fen-Er Chen   +10 more
doaj   +1 more source

Side‐Chain‐Induced Interlayer Slipping in Metalloporphyrin COFs Enables Microenvironment and Spin‐State Regulation for Photocatalytic CO2 Reduction

Advanced Materials, EarlyView.
Alkoxy chain length drives a continuous transition from eclipsed AA to a serrated, slipped AA* configuration over Co‐porphyrin COFs. A moderate slip both contracts the pore channel to enrich CO2 and suppress hydrogen evolution, and enhances collective high‐spin of Co sites, which delivers a record CO production rate with high selectivity.
Jie He, Qingxuan Chen, Minxian Zhang, Wenhao Zhao, Aoni Xu, Jinqiang Zhang, Hongqi Sun, Shaobin Wang, Xiaoguang Duan   +8 more
wiley   +1 more source

Multiple Hydrogen-Bond Activation in Asymmetric Brønsted Acid Catalysis

, 2018
An efficient protocol for the asymmetric synthesis of chiral tetrahydroquinolines bearing multiple stereogenic centers by means of asymmetric Brønsted acid catalysis was developed.
Atodiresei, Iuliana, Hsiao, Chien-Chi, Liao, Hsuan-Hung, Rueping, Magnus   +3 more
core   +1 more source

Decoding Synergistic Pathways in Bimetallic MOFs for Advanced Oxidation Processes

Advanced Materials, EarlyView.
This review presents a unified framework linking metal pairing and framework design with electronic structure, redox cycling, oxidant activation, reactive‐species generation, and catalytic performance across photocatalytic and oxidant‐based BMOF‐AOPs. The resulting design principles guide the development of hydrolytically stable and efficient BMOFs for
Karim El‐Naggar, Huayang Zhang, Shaobin Wang   +2 more
wiley   +1 more source

Metal-Organic Frameworks: Defects, Spectroscopy and Catalysis [PDF]

, 2020
In this PhD thesis we have studied the chemistry of defects within Metal-Organic Frameworks (MOFs) as well as the properties of the related Defect-Engineered Metal-Organic Frameworks (DEMOFs).
Sub Inorganic Chemistry and Catalysis, Inorganic Chemistry and Catalysis, Rivera Torrente, Miguel   +2 more
core  

Lattice Strain and Built‐In Field Synergistically Boost Urea Oxidation via Dynamic NiOOH Mediation at Multiphase Heterointerfaces

Advanced Materials, EarlyView.
A sulfur‐doped lignin‐derived carbon‐coated Ni‐NiO‐MoO2 nanorod array was synthesized, exhibiting enhanced UOR performance ‐ due to lattice‐strain and built‐in electric field effects by multiphase heterogeneous interface in Ni‐NiO‐MoO2@SC, excellent corrosion resistance, mass‐transport ability, and long‐term stability (500 mA cm−2 at 1.53 V for 500 h ...
Jiawei Li, Liancen Li, Guangfu Qian, Zishan Cai, Yiping Cao, Yihao Xu, Ruyu Zhang, Jinli Chen, Changzhou Chen, Panagiotis Tsiakaras   +9 more
wiley   +1 more source

Chiral phosphine-phosphoramidite ligands in asymmetric catalysis

, 2016
Chiral phosphine-phosphoramidite ligands, featuring ready availability, easy modification, and stability towards air and moisture, have recently emerged as a new kind of robust ligands for asymmetric catalysis.
Hu, Xiang-Ping, Hou, Chuan-Jin, Chen, Xiu-Shuai   +2 more
core   +1 more source

Understanding Operando Water Management in Hydroxide‐Exchange‐Membrane Fuel Cells

Advanced Materials Interfaces, EarlyView.
Effective water management is vital for high‐performance hydroxide‐exchange‐membrane fuel cells. Using a custom water‐flux station, this study quantifies how membrane thickness, microporous layers, and operating conditions dictate internal water transport.
Catherine M. Weiss, Shiyi Wang, Brian P. Setzler, Yushan Yan, Adam Z. Weber   +4 more
wiley   +1 more source

Controlled Growth of Boron Nitride in Various Phases

Advanced Materials Interfaces, EarlyView.
Phase‐selective boron nitride growth is presented as a unified materials‐design problem across hexagonal, rhombohedral, cubic, and amorphous phases. By linking synthesis routes to thermodynamic stability, kinetic accessibility, surface diffusion, interfacial templating, and energetic activation, this review clarifies how bonding and stacking are ...
Pan Wu, Kanghao Xie, Jiajie Qi, Xiaorui Zheng, Kaihui Liu, Xuedong Bai, Li Wang   +6 more
wiley   +1 more source

Lewis Acidity in Cracking and Polymerization Catalysis [PDF]

, 2019
The aim of this PhD thesis was to provide insight into the nature and variety of Lewis acidity in solid acid catalysts and to clarify the role of Lewis acid sites in fluid catalytic cracking (FCC) and metallocene-based olefin polymerization catalysis ...
Sub Inorganic Chemistry and Catalysis, Inorganic Chemistry and Catalysis, Velthoen, Marjolein Elise Zoë   +2 more
core