Results 1 to 10 of about 14,639 (100)
A Stereoselective Synthesis of (−)-Tetrodotoxin [PDF]
Journal of the American Chemical Society, 2003 An asymmetric synthesis of the fugu fish poison, (-)-tetrodotoxin, is described. The route to this extraordinary target employs a number of unique transformations, foremost of which are two stereospecific C-H bond functionalization reactions. Accordingly, Rh-catalyzed carbene and nitrene C-H insertions facilitate rapid entry to the cyclohexane core of ...
Andrew, Hinman, J, Du Bois
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Stereoselective Synthesis of Microcarpalide. [PDF]
ChemInform, 2002 AbstractFor Abstract see ChemInform Abstract in Full Text.
Juan, Murga +4 more
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Stereoselective Synthesis of (−)-Spicigerolide [PDF]
The Journal of Organic Chemistry, 2009 (-)-Spicigerolide was stereoselectively synthesized from a protected (S)-lactaldehyde. The synthesis of the polyacetylated framework relied on two Zn-mediated stereoselective additions of alkynes to aldehydes as well as a regiocontrolled [3,3]-sigmatropic rearrangement of an allylic acetate.
Georges, Yohan +2 more
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Stereoselective Radical Translocations
CHIMIA, 2008 The stereochemical outcome of intramolecular radical mediated hydrogen transfer (= radical translocation) is discussed. Low to excellent levels of stereocontrol are observed making such processes attractive for applications in target-oriented synthesis.
Renaud, Philippe +5 more
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The Stereoselectivity of Drug Action [PDF]
Pharmacology & Toxicology, 1989 Pharmacologists and toxicologists are in the midst of demonstrating the importance of spatial (three-dimensional) molecular features in the functions of biological systems and in the therapeutic actions and side effects of drugs. Recent findings indicate that spatial features in a variety of biologically active molecules play a decisive role in many ...
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Stereoselective arene formation [PDF]
Chemical Society Reviews, 2018 The common perception of arenes as flat and symmetric entities is juxtaposed to the counterintuitive circumstance that stereoselective arene formation offers a means to prepare an exceptional range of chiral aromatic structures in isomerically enriched form.
Achim Link, Christof Sparr
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A stereoselective synthesis of (+)-boronolide [PDF]
Tetrahedron Letters, 2000 A stereoselective synthesis of (+)-boronolide is described. The key steps involve a stereoselective reduction of an α-hydroxy ketone, allylation of an α-hydroxy aldehyde and a ring-closing olefin metathesis of a homoallylic alcohol derived acrylate ester utilizing Grubbs' catalyst.
Arun K, Ghosh, Geoffrey, Bilcer
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Stereoselective Synthesis of Baulamycin A
The Journal of Organic Chemistry, 2020 New structural classes of antibiotics are rare, structurally novel broad-spectrum antibiotics exceptionally so. The recently discovered baulamycins constitute a remarkable example of these highly prized compounds and, as such, have attracted considerable attention in the form of both synthetic efforts and biological studies.
Jonathan R. Thielman +2 more
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On the stereoselective synthesis of estrone
Tetrahedron Letters, 1960 By application of the Robinson-Mannich reaction 6-p-anisyl-2-oxocyclohex-6-ene-1-acetic acid (VIa); 6-p-anisyl-2-oxo-3-methylcyclohex-6-ene-1-acetic acid (VIb), and the corresponding 3-alkoxycarbonyI deri-vatives (VIc, d, e, and f) have been prepared.
Banerjee, DK, Sivanandaiah, KM
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, 2014 Citation: 'stereoselectivity' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.S05991 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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