Results 1 to 10 of about 29,422 (294)
Molecules, 2014 Chlorinated ethenes are prevalent groundwater contaminants. To better constrain (bio)chemical reaction mechanisms of reductive dechlorination, the position-specificity of reductive trichloroethene (TCE) dehalogenation was investigated.
Stefan Cretnik +4 more
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Regioselective Substitution of BINOL
Chemical Reviews1,1'-Bi-2-naphthol (BINOL) has been extensively used as the chirality source in the fields of molecular recognition, asymmetric synthesis, and materials science. The direct electrophilic substitution at the aromatic rings of the optically active BINOL has been developed as one of the most convenient strategies to structurally modify BINOL for diverse ...
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Ligand control of regioselectivity in palladium-catalyzed heteroannulation reactions of 1,3-Dienes
Nature CommunicationsOlefin carbofunctionalization reactions are indispensable tools for constructing diverse, functionalized scaffolds from simple starting materials. However, achieving precise control over regioselectivity in intermolecular reactions remains a formidable ...
Dasha Rodina +2 more
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Molecules, 2016 A novel selective and substrate-dependent synthetic protocol has been developed towards the synthesis of various fluorine-containing, highly functionalized cycloalkane derivatives.
Attila Márió Remete +4 more
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Journal of Lipid Research, 2010 Cytochromes P450 (CYPs) metabolize polyunsaturated long-chain fatty acids (PUFA-LC) to several classes of oxygenated metabolites. Through use of human recombinant CYPs, we recently showed that CYP1A1, -2C19, -2D6, -2E1, and -3A4 are mainly hydroxylases ...
Danièle Lucas +7 more
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Beilstein Journal of Organic Chemistry, 2020 The first example of the cycloaddition of in situ-generated azomethine imine under microwave conditions is described. The reaction of 6-aryl-1,5-diazabicyclo[3.1.0]hexanes with 1,3-diphenylprop-2-en-1-ones proceeds regio- and stereoselectively giving ...
Alexander P. Molchanov +3 more
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Beilstein Journal of Organic Chemistry, 2015 Secondary phosphine oxides react with vinyl sulfides (both alkyl- and aryl-substituted sulfides) under aerobic and solvent-free conditions (80 °C, air, 7–30 h) to afford 1-hydroxy-2-(organosulfanyl)ethyl(diorganyl)phosphine oxides in 70–93% yields.
Svetlana F. Malysheva +6 more
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Study on the Alkylation Reactions of N(7)-Unsubstituted 1,3-Diazaoxindoles
Molecules, 2017 The chemistry of the 5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one (1,3-diazaoxindole) compound family, possessing a drug-like scaffold, is unexplored. In this study, the alkylation reactions of N(7)-unsubstituted 5-isopropyl-1,3-diazaoxindoles bearing ...
Eszter Kókai +5 more
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Regioselective Deacetylation in Nucleosides and Derivatives
ChemBioChemAbstractNucleoside analogues are a promising class of natural compounds in the pharmaceutical industry, and many antiviral, antibacterial and anticancer drugs have been created through structural modification of nucleosides scaffold. Acyl protecting groups, especially the acetyl group, play an important role in the protection of hydroxy groups in ...
Charis Grabbe, Li Cai
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ChemistryEuropeRegioselective synthesis is a crucial concept in organic chemistry, enabling the selective formation of different regioisomers from the same type of starting materials.
Eva Bednářová +7 more
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