Results 31 to 40 of about 29,422 (294)

RegioSQM20:improved prediction of the regioselectivity of electrophilic aromatic substitutions

, 2020
We present RegioSQM20, a new version of RegioSQM (Chem. Sci. 2018, 9, 660), which predicts the regioselectivities of electrophilic aromatic substitution (EAS) re- actions from the calculation of proton affinities.
Andreas, Gõller, Nicolai, Ree, Jensen, Jan H., Göller, Andreas H., Jan H., Jensen, Ree, Nicolai   +5 more
core   +1 more source

Reversal of Regioselectivity in Reactions of Donor-Acceptor Cyclopropanes with Eelectrophilic Olefins

, 2021
Cyclopropanes bearing donor and acceptor groups at the opposite ends of the C-C bond should react with both nucleophiles and electrophiles. Their reactivity towards nucleophiles is well explored while only few specific electrophilic reagents give desired
Jakub, Durka, Michał, Ociepa, Joanna , Turkowska, Dorota, Gryko   +3 more
core   +1 more source

Ligand Control of Regioselectivity in Palladium-Catalyzed Heteroannulation Reactions of 1,3-Dienes

, 2023
Olefin carbofunctionalization reactions are indispensable tools for constructing diverse, functionalized scaffolds from simple starting materials. However, achieving precise control over regioselectivity in intermolecular reactions remains a formidable ...
Shauna, Paradine, Dasha, Rodina, Jakub, Vaith   +2 more
core   +1 more source

Deprotometalation-Iodolysis and Direct Iodination of 1-Arylated 7-Azaindoles: Reactivity Studies and Molecule Properties

Molecules, 2021
Five protocols were first compared for the copper-catalyzed C-N bond formation between 7-azaindole and aryl/heteroaryl iodides/bromides. The 1-arylated 7-azaindoles thus obtained were subjected to deprotometalation-iodolysis sequences using lithium 2,2,6,
Mohamed Yacine Ameur Messaoud, Ghenia Bentabed-Ababsa, Ziad Fajloun, Monzer Hamze, Yury S. Halauko, Oleg A. Ivashkevich, Vadim E. Matulis, Thierry Roisnel, Vincent Dorcet, Florence Mongin   +9 more
doaj   +1 more source

Regioselective Reduction of β‐Enaminoesters

Synthetic Communications, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Hussaini, SR, Moloney, M
openaire   +1 more source

Highly Regioselective Friedländer Reaction [PDF]

Organic Letters, 2001
[reaction: see text]. A highly regioselective Friedländer reaction is described. By introduction of a phosphonate group at one of the alpha-carbons of a ketone, regioselectivity can be perfectly controlled.
Y, Hsiao, N R, Rivera, N, Yasuda, D L, Hughes, P J, Reider   +4 more
openaire   +2 more sources

ALLYLATION OF ARYL GRIGNARD REAGENTS IN THE PRESENCE OF TRANSITION METAL CATALYSIS AND ORGANIC CATALYSIS

Journal of the Turkish Chemical Society, Section A: Chemistry, 2017
The allylation yield and regioselectivity of phenyl Grignard reagent in THF was investigated in the presence of complexed transition metals and also uncomplexed or complexed transition metal salts.
Melike Kalkan
doaj   +1 more source

Molecular Basis of C-30 Product Regioselectivity of Legume Oxidases Involved in High-Value Triterpenoid Biosynthesis

Frontiers in Plant Science, 2019
The triterpenes are structurally diverse group of specialized metabolites with important roles in plant defense and human health. Glycyrrhizin, with a carboxyl group at C-30 of its aglycone moiety, is a valuable triterpene glycoside, the production of ...
Much Zaenal Fanani, Ery Odette Fukushima, Ery Odette Fukushima, Satoru Sawai, Satoru Sawai, Satoru Sawai, Satoru Sawai, Jianwei Tang, Masato Ishimori, Hiroshi Sudo, Kiyoshi Ohyama, Kiyoshi Ohyama, Hikaru Seki, Hikaru Seki, Kazuki Saito, Kazuki Saito, Toshiya Muranaka, Toshiya Muranaka   +17 more
doaj   +1 more source

Modulating regioselectivity of CYP107J3-catalyzed isophorone hydroxylation by disrupting the hydrophobic balance of the substrate binding pocket

Green Synthesis and Catalysis
4-Hydroxyisophorone (4HIP) is an oxygenated intermediate derived from isophorone, serving as an important flavor and fragrance and chiral synthon of pharmaceutical drugs.
Meng Dai, Xiaojuan Yu, Xiaogang Peng, Zhiyong Guo, Huili Yu, Aitao Li   +5 more
doaj   +1 more source

Jumping in the Chiral Pool: Asymmetric Hydroaminations with Early Metals

Molecules, 2023
The application of early-metal-based catalysts featuring natural chiral pool motifs, such as amino acids, terpenes and alkaloids, in hydroamination reactions is discussed and compared to those beyond the chiral pool.
Sebastian Notz, Sebastian Scharf, Heinrich Lang   +2 more
doaj   +1 more source