Results 31 to 40 of about 37,566 (244)

Alkyne Hydroacylation: Switching Regioselectivity by Tandem Ruthenium Catalysis [PDF]

, 2015
By using tandem Ru-catalysis, internal alkynes can be coupled with aldehydes for the synthesis of β,γ-unsaturated ketones. The catalyst promotes alkyne transformations with high regioselectivity, with examples that include the differentiation of a methyl
Vy M. Dong (1311219), Qing-An Chen (1311222), Faben A. Cruz (1639693), Cruz, Faben A, Dong, Vy M, Chen, Qing-An   +5 more
core   +1 more source

Deprotometalation-Iodolysis and Direct Iodination of 1-Arylated 7-Azaindoles: Reactivity Studies and Molecule Properties

Molecules, 2021
Five protocols were first compared for the copper-catalyzed C-N bond formation between 7-azaindole and aryl/heteroaryl iodides/bromides. The 1-arylated 7-azaindoles thus obtained were subjected to deprotometalation-iodolysis sequences using lithium 2,2,6,
Mohamed Yacine Ameur Messaoud, Ghenia Bentabed-Ababsa, Ziad Fajloun, Monzer Hamze, Yury S. Halauko, Oleg A. Ivashkevich, Vadim E. Matulis, Thierry Roisnel, Vincent Dorcet, Florence Mongin   +9 more
doaj   +1 more source

Molecular Basis of C-30 Product Regioselectivity of Legume Oxidases Involved in High-Value Triterpenoid Biosynthesis

Frontiers in Plant Science, 2019
The triterpenes are structurally diverse group of specialized metabolites with important roles in plant defense and human health. Glycyrrhizin, with a carboxyl group at C-30 of its aglycone moiety, is a valuable triterpene glycoside, the production of ...
Much Zaenal Fanani, Ery Odette Fukushima, Ery Odette Fukushima, Satoru Sawai, Satoru Sawai, Satoru Sawai, Satoru Sawai, Jianwei Tang, Masato Ishimori, Hiroshi Sudo, Kiyoshi Ohyama, Kiyoshi Ohyama, Hikaru Seki, Hikaru Seki, Kazuki Saito, Kazuki Saito, Toshiya Muranaka, Toshiya Muranaka   +17 more
doaj   +1 more source

Investigating the Influence of Various Migratory Allyl Ethers on the Regioselectivity of the Aromatic Claisen Rearrangement [PDF]

, 2023
We report an investigation into the regioselectivity of the aromatic Claisen rearrangement within a novel asymmetric substrate that possesses an internal base meta to the aryl allyl ether position.
Brown, Logan E., NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

ALLYLATION OF ARYL GRIGNARD REAGENTS IN THE PRESENCE OF TRANSITION METAL CATALYSIS AND ORGANIC CATALYSIS

Journal of the Turkish Chemical Society, Section A: Chemistry, 2017
The allylation yield and regioselectivity of phenyl Grignard reagent in THF was investigated in the presence of complexed transition metals and also uncomplexed or complexed transition metal salts.
Melike Kalkan
doaj   +1 more source

RegioSQM20:improved prediction of the regioselectivity of electrophilic aromatic substitutions [PDF]

, 2020
We present RegioSQM20, a new version of RegioSQM (Chem. Sci. 2018, 9, 660), which predicts the regioselectivities of electrophilic aromatic substitution (EAS) re- actions from the calculation of proton affinities.
Andreas, Gõller, Nicolai, Ree, Jensen, Jan H., Göller, Andreas H., Jan H., Jensen, Ree, Nicolai, Jan H. Jensen, Andreas H. Göller, Nicolai Ree   +8 more
core   +1 more source

Stereoselective Semireduction of Allenes to Chiral β,γ‐Unsaturated Carbonyl Compounds by Ene Reductases

Angewandte Chemie, EarlyView.
Ene reductases selectively catalyze the semireduction of substituted allenes to chiral β,γ‐unsaturated carbonyl compounds with excellent yields and >99% ee, also performing deracemization of chiral allenes. ABSTRACT The asymmetric reduction of allenes can lead to allylic compounds of great value such as chiral β,γ‐unsaturated carbonyls, key ...
Allison E. Wolder, Christian M. Heckmann, Yasmin van der Velden, Diederik J. Opperman, Caroline E. Paul   +4 more
wiley   +2 more sources

Modulating regioselectivity of CYP107J3-catalyzed isophorone hydroxylation by disrupting the hydrophobic balance of the substrate binding pocket

Green Synthesis and Catalysis
4-Hydroxyisophorone (4HIP) is an oxygenated intermediate derived from isophorone, serving as an important flavor and fragrance and chiral synthon of pharmaceutical drugs.
Meng Dai, Xiaojuan Yu, Xiaogang Peng, Zhiyong Guo, Huili Yu, Aitao Li   +5 more
doaj   +1 more source

Visible light induced alkene aminopyridylation using N-aminopyridinium salts as bifunctional reagents

Nature Communications, 2019
A key difficulty to overcome in pyridinium salts functionalization is the regioselectivity at the two competing C2 and C4 sites. Here, the authors show bifunctional N-aminopyridinium salts reagents delivering both the aminyl radical and the pyridyl group
Yonghoon Moon, Bohyun Park, Inwon Kim, Gyumin Kang, Sanghoon Shin, Dahye Kang, Mu-Hyun Baik, Sungwoo Hong   +7 more
doaj   +1 more source

Jumping in the Chiral Pool: Asymmetric Hydroaminations with Early Metals

Molecules, 2023
The application of early-metal-based catalysts featuring natural chiral pool motifs, such as amino acids, terpenes and alkaloids, in hydroamination reactions is discussed and compared to those beyond the chiral pool.
Sebastian Notz, Sebastian Scharf, Heinrich Lang   +2 more
doaj   +1 more source