Results 21 to 30 of about 37,566 (244)

Enzyme modification using mutation site prediction method for enhancing the regioselectivity of substrate reaction sites

open access: yesScientific Reports, 2021
Enzymes with low regioselectivity of substrate reaction sites may produce multiple products from a single substrate. When a target product is produced industrially using these enzymes, the production of non-target products (byproducts) causes adverse ...
Jinzen Ikebe   +4 more
doaj   +1 more source

Insights into the Mechanism and Regioselectivity of Palladium-Catalyzed Arylation of α,β-Unsaturated Ketones [PDF]

open access: yes, 2023
Transition-metal catalyzed coupling reactions of carbonyl compounds using simple chemical feedstocks have become a cornerstone of modern synthetic organic chemistry.
Xiaoxi, Su   +3 more
core   +2 more sources

Highly efficient and enzymatic regioselective undecylenoylation of gastrodin in 2-methyltetrahydrofuran-containing systems. [PDF]

open access: yesPLoS ONE, 2014
Highly efficient and regioselective acylation of pharmacologically interesting gastrodin with vinyl undecylenic acid has been firstly performed through an enzymatic approach. The highest catalytic activity and regioselectivity towards the acylation of 7'-
Rongling Yang   +5 more
doaj   +1 more source

Regioselective conversion of epoxides to β-acetoxy alcohols catalyzed by a novel green and recyclable phase transfer catalyst [PDF]

open access: yesشیمی کاربردی روز, 2018
A new mild and efficient procedure for the ring opening of epoxides by acetate anion in the presence of catalytic amounts of silica-bound polyethylene glycol substituted 1-methylimidazolium bromide, SiO2-PEG-ImBr, as an effective heterogeneous phase ...
ندا عیاشی   +2 more
doaj   +1 more source

Origin of the Anti-Markovnikov Hydroamination of Alkenes Catalyzed by L−Au(I) Complexes: Coordination Mode Determines Regioselectivity [PDF]

open access: yes, 2019
The reaction mechanism and regioselectivity for the gold(I)-catalyzed hydroamination reaction of terminal alkenes are analyzed by means of density functional theory (DFT) calculations.
Couce-Ríos, A.   +3 more
core   +3 more sources

Electronic and Steric Effects Control Regioselectivity in Alkyne Migratory Insertion during Ni-Catalyzed Indenone Synthesis

open access: yes, 2023
Many useful transition-metal-catalyzed reactions depend on the migratory insertion of an alkyne into a metal–carbon bond. Steric effects, electronic effects, and coordinating directing groups have all been shown to control product distributions in ...
Logan M. Whitt (14657791)   +5 more
core   +1 more source

An efficient synthesis of novel triazoles incorporating barbituric motifs via [3+2] cycloaddition reaction: An experimental and theoretical study [PDF]

open access: yesJournal of the Serbian Chemical Society, 2018
In this work, the synthesis of novel triazole derivatives with barbituric motifs in good yields is described. The alkyne was prepared through the Knoevenagel reaction of barbituric derivatives with ortho and para O-propargylated hydroxybenzaldehyde.
Darroudi Mahdieh   +2 more
doaj   +1 more source

The Highly Regioselective Synthesis of Novel Imidazolidin-2-Ones via the Intramolecular Cyclization/Electrophilic Substitution of Urea Derivatives and the Evaluation of Their Anticancer Activity

open access: yesMolecules, 2021
A series of novel 4-(het)arylimidazoldin-2-ones were obtained by the acid-catalyzed reaction of (2,2-diethoxyethyl)ureas with aromatic and heterocyclic C-nucleophiles.
Almir S. Gazizov   +10 more
doaj   +1 more source

The Nitrilimine–Alkene Cycloaddition Regioselectivity Rationalized by Density Functional Theory Reactivity Indices

open access: yesMolecules, 2017
Conventional frontier molecular orbital theory is not able to satisfactorily explain the regioselectivity outcome of the nitrilimine–alkene cycloaddition.
Giorgio Molteni, Alessandro Ponti
doaj   +1 more source

Heavy atom effects in the Paternò–Büchi reaction of pyrimidine derivatives with 4,4’-disubstituted benzophenones

open access: yesBeilstein Journal of Organic Chemistry, 2011
The regioselectivity and the photochemical efficiency were investigated in the Paternò–Büchi reaction of 1,3-dimethylthymine (DMT) and 1,3-dimethyluracil (DMU) with benzophenone (1b) and some 4,4’-disubstituted derivatives (dimethoxy (1a), difluoro (1c),
Feng-Feng Kong   +2 more
doaj   +1 more source

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