Results 41 to 50 of about 29,422 (294)

regioselectivity (regioselective) [PDF]

, 2014
Citation: 'regioselectivity (regioselective)' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.R05243 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
openaire   +1 more source

Regioselectivity-Switchable Catalytic Annulations of Alkynyl α‑Diketones and α‑Cyanoketones

, 2019
Regioselectivity-switchable reactions hold irreplaceable importance in the construction of diversified architectures. In this work, Brønsted base-catalyzed regioselectivity-switchable annulations between alkynyl α-diketones and α-cyanoketones have been ...
Xinqiang Fang, Rui Liu, Banoth Paplal, Rui Liu (54031), Shuhua Liu (1598038), Jinggong Liu, Jinggong Liu (1528981), Shuang Yang (64650), Zhizhou Chen, Banoth Paplal (8072522), Shuang Yang, Sakkani Nagaraju, Shuhua Liu, Zhizhou Chen (8072519), Xinqiang Fang (1904908), Sakkani Nagaraju (8072516)   +15 more
core   +1 more source

Regioselectivity Control of the Ring Opening of Epoxides With Sodium Azide in a Microreactor [PDF]

, 2012
The reaction of different types of aromatic and aliphatic epoxides with sodium azide to give vicinal azido alcohols was studied in a microreactor with and without pillars in the channels.
Joe, Daejune, Rajesh Munirathinam, Joe, D.J., Daejune Joe, Jurriaan Huskens, Munirathinam, Rajesh, Willem Verboom, Huskens, Jurriaan, Verboom, Willem   +8 more
core   +1 more source

Origins of Internal Regioselectivity in Copper-Catalyzed Borylation of Terminal Alkynes

, 2021
Installation of a boron functionality into a more substituted carbon of terminal alkynes has been a challenging issue in chemical synthesis, since inherently Lewis acidic boron moieties, in principle, favor their attachment to a terminal carbon.
Takumi, Tsushima, Hiroto, Yoshida, Masaaki, Nakamoto, Hideya, Tanaka, Kazuki, Nakanishi   +4 more
core   +1 more source

Improving regioselectivity of phenylalanine aminomutase from Taxus chinensis by semi-rational mutagenesis for the biocatalytic amination of cinnamates

Frontiers in Bioengineering and Biotechnology
The occupancy of the binding pocket by the substrate ultimately determines the outcome of enzyme catalysis. Previous engineering and substrate scope of phenylalanine aminomutase from Taxus chinensis (TcPAM) has generated valuable knowledge about the ...
Tao Tang, Miao Wang, Yunyun Zhang, Yijun Chen   +3 more
doaj   +1 more source

Visible light induced alkene aminopyridylation using N-aminopyridinium salts as bifunctional reagents

Nature Communications, 2019
A key difficulty to overcome in pyridinium salts functionalization is the regioselectivity at the two competing C2 and C4 sites. Here, the authors show bifunctional N-aminopyridinium salts reagents delivering both the aminyl radical and the pyridyl group
Yonghoon Moon, Bohyun Park, Inwon Kim, Gyumin Kang, Sanghoon Shin, Dahye Kang, Mu-Hyun Baik, Sungwoo Hong   +7 more
doaj   +1 more source

Regioselective Alkylation of Pyridinium Riboses [PDF]

European Journal of Organic Chemistry, 2020
The nucleophilic addition of alkyl, benzyl, and allyl organozinc reagents to protected pyridinium riboses proceeds under mild conditions and with yields of > 90 % in several cases and complete regioselectivity for the 4‐position.
Farbod Salahi, Olaf Wiest
openaire   +2 more sources

Metal-Free Regiodivergent Addition of Carbon Nucleophiles to α,β-Unsaturated Electrophiles

Molecules, 2017
A mild and metal-free regiodivergent addition of carbon nucleophiles to α,β-unsaturated electrophiles was developed. Total 1,2-regioselectivity was observed in the addition of nitrobenzyl chloride derivative 1 to α,β-unsaturated aldehydes 2 in the ...
Cédric Spitz, Alain G. Giuglio-Tonolo, Thierry Terme, Patrice Vanelle   +3 more
doaj   +1 more source

Merging Biocatalysis and Chemocatalysis in Flow: State‐of‐the‐Art and Future Directions for Sustainable Synthesis

Angewandte Chemie, EarlyView.
This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis, Matteo Damian, Francesco G. Mutti   +2 more
wiley   +2 more sources

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources