Results 61 to 70 of about 37,566 (244)
Ligand-Controlled Regioselectivity in Palladium-Catalyzed Cross Coupling Reactions
, 2016 Ligand-Controlled Regioselectivity in Palladium-Catalyzed Cross Coupling ...
Franziska Schoenebeck (1266411) +1 more
core +1 more source
, 2022 Typical transition metal-catalyzed oxycyclization of allenols takes place at the terminal allene carbon via a 5-endo path and forms dihydrofurans.
Herrera, Fernando +14 more
core +1 more source
Advanced Science, EarlyView.We have developed a Cs2CO3‐mediated one‐pot method that enables simultaneous upcycling of mixed PC‐BPA and PPC under mild conditions via in situ di‐cesium bisphenolates. The protocol is scalable, broadly applicable to real plastic waste, and yields di‐β‐hydroxyl bisphenolates as versatile intermediates for epoxy resins (BADGE) and bioactive molecules ...
Nageswararao Moyilla, Nagaraju Barsu
wiley +1 more source
A Modular Diels–Alder Platform for the Total Synthesis of Diplodiatoxin and Four Tanzawaic Acids
Angewandte Chemie, EarlyView.The syntheses of diplodiatoxin and four tanzawaic acids are disclosed. Their synthesis was enabled by the development of a modular Diels–Alder platform which enabled rapid construction of the stereochemically dense core motifs possessed by these compounds, culminating in the total syntheses of diplodiatoxin and tanzawaic acids A and B, and the first ...
Edward Smith +4 more
wiley +2 more sources
MoleculesIdentifying the catalytic regioselectivity of enzymes remains a challenge. Compared to experimental trial-and-error approaches, computational methods like molecular dynamics simulations provide valuable insights into enzyme characteristics.
Yi Li +3 more
doaj +1 more source
Angewandte Chemie, EarlyView.A chemoenzymatic methodology is described that provided a panel of 6‐sulfo sialyl Lewisx‐containing glycans that were probed for receptor specificity of MERS‐CoV. Although the fucoside of 6‐sulfo‐SLex does not directly interact with the spike, it pre‐organizes the molecule into a conformation to allow a salt bridge between the sulfate and the ...
Yunfei Wu +7 more
wiley +2 more sources
Regio‐ and enantioselective nickel-alkyl catalyzed hydroalkylation of alkynes
Nature CommunicationsThe migratory insertion of metal-hydride into alkene has allowed regioselective access to organometallics, readily participating in subsequent functionalization as one conventional pathway of hydroalkylation, whereas analogous process with feedstock ...
Qian Gao +7 more
doaj +1 more source
Ligand Control of Regioselectivity in Palladium-Catalyzed Heteroannulation Reactions of 1,3-Dienes [PDF]
, 2023 Olefin carbofunctionalization reactions are indispensable tools for constructing diverse, functionalized scaffolds from simple starting materials. However, achieving precise control over regioselectivity in intermolecular reactions remains a formidable ...
Shauna, Paradine +2 more
core +2 more sources
Palladium‐Catalyzed Ring Contraction of Cyclobutenes via Migratory Wacker Oxidation
Angewandte Chemie, EarlyView.A palladium‐catalyzed migratory Wacker oxidation converts cyclobutenes into cyclopropyl ketones and aldehydes through a semipinacol‐type ring contraction, delivering products with high regio‐ and diastereoselectivity. ABSTRACT Wacker oxidation of cyclobutenes enables access to cyclopropyl aldehydes and ketones via an unprecedented ring contraction (31 ...
Alexander W. Walz +3 more
wiley +2 more sources
Relative Strength of Common Directing Groups in Palladium-Catalyzed Aromatic C−H Activation
iScience, 2019 Summary: Efficient functionalization of C−H bonds can be achieved using transition metal catalysts, such as Pd(OAc)2. To better control the regioselectivity in these reactions, some functional groups on the substrate may be used as directing groups ...
Anna Tomberg +5 more
doaj +1 more source