Results 21 to 30 of about 27,319 (289)

Stereoselective Toxicokinetic and Distribution Study on the Hexaconazole Enantiomers in Mice

Toxics, 2023
Hexaconazole (Hex) has been widely used in agricultural products, and its residues may pose a potential risk to human health. However, the metabolic behavior of Hex enantiomers in mammal organisms is still unknown, which is important for evaluating the ...
Guofei Luo, Junxiao Pang, Dali Sun, Qinghai Zhang   +3 more
doaj   +1 more source

‐Stereoselectivity

, 2021
International audienceAryl- and hetaryl-substituted acetylenes undergo regio- and stereoselective silylzincation by reaction with [(Me3Si)3Si]2Zn in the presence of Et2Zn (10–110 mol%) as additive.
Martin Oestreich, Gerard, Hélène, Chemla, Fabrice, Karen de la Vega‐Hernández, Olivier Jackowski, Stéphanie Halbert, Alejandro Perez‐Luna, Franck Ferreira, Guégan, Frédéric, Sanz García, Juan, Fopp, Carolin, Hélène Gerard, Halbert, Stéphanie, Juan Sanz García, Jackowski, Olivier, Elise Romain, Oestreich, Martin, Fabrice Chemla, de La Vega-Hernández, Karen, Frédéric Guégan, Romain, Elise, Carolin Fopp, Ferreira, Franck, Perez-Luna, Alejandro   +23 more
core   +1 more source

Synthesis of Polysubstituted Ferrocenesulfoxides

Molecules, 2022
The purpose of the study is to design synthetic methodologies, especially directed deprotometalation using polar organometallic reagents, to access polysubstituted ferrocenesulfoxides.
Min Wen, William Erb, Florence Mongin, Yury S. Halauko, Oleg A. Ivashkevich, Vadim E. Matulis, Thierry Roisnel   +6 more
doaj   +1 more source

Tetrahydropyridines’ Stereoselective Formation, How Lockdown Assisted in the Identification of the Features of Its Mechanism

Molecules, 2022
The multicomponent reaction of aldehydes, cyano-containing C-H acids, esters of 3-oxocarboxylic acid and ammonium acetate led to unexpected results.
Anatoly N. Vereshchagin, Taigib M. Iliyasov, Kirill A. Karpenko, Radmir N. Akchurin, Mikhail E. Minyaev   +4 more
doaj   +1 more source

Intramolecular Diels-Alder reactions of cycloalkenones: stereoselectivity, Lewis acid acceleration, and halogen substituent effects. [PDF]

, 2014
The intramolecular Diels-Alder reactions of cycloalkenones and terminal dienes occur with high endo stereoselectivity, both thermally and under Lewis-acidic conditions.
Danishefsky, Samuel J, Paton, RS, Houk, KN, Pham, HV, Danishefsky, SJ, Pham, Hung V, Ross, AG, Paton, Robert S, Ross, Audrey G   +8 more
core   +1 more source

Manipulating Stereoselectivity of Parahydrogen Addition to Acetylene to Unravel Interconversion of Ethylene Nuclear Spin Isomers

, 2023
Symmetric molecules exist as distinct nuclear spin isomers (NSIMs). A deeper understanding of their properties, including interconversion, requires efficient techniques for NSIMs enrichment.
Ivan V., Skovpin, Larisa M., Kovtunova, Dudari B., Burueva, Sergey V. , Sviyazov, Nikita V., Chukanov, Alexander Yu., Stakheev, Igor V., Koptyug, Simon V., Babenko   +7 more
core   +1 more source

Analysis of chiral non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac binding with HSA

Journal of Pharmaceutical Analysis, 2011
The protein binding of non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac with human serum albumin (HSA) was investigated using indirect chiral high performance liquid chromatography (HPLC) and ultrafiltration techniques. S-(–)-
Chang-Chuan Guo, Yi-Hong Tang, Hai-Hong Hu, Lu-Shan Yu, Hui-Di Jiang, Su Zeng   +5 more
doaj   +1 more source

Stereoselectivity of Interaction of Nonsteroidal Anti-Inflammatory Drug S-Ketoprofen with L/D-Tryptophan in Phospholipid Membranes

Membranes, 2022
The mechanisms of stereoselectivity of the interaction of chiral drugs with active sites of enzymes and cell receptors attract significant attention.
Anna V. Mastova, Olga Yu. Selyutina, Nikolay E. Polyakov   +2 more
doaj   +1 more source

The Synthesis of α-Aminophosphonates via Enantioselective Organocatalytic Reaction of 1-(N-Acylamino)alkylphosphonium Salts with Dimethyl Phosphite

Molecules, 2020
α-Aminophosphonic acids are phosphorus analogues of α-amino acids. Compounds of this type find numerous applications in medicine and crop protection due to their unique biological activities.
Alicja Walęcka-Kurczyk, Krzysztof Walczak, Anna Kuźnik, Sebastian Stecko, Agnieszka Październiok-Holewa   +4 more
doaj   +1 more source

Predicting Glycosylation Stereoselectivity Using Machine Learning

, 2020
Predicting the stereochemical outcome of chemical reactions is challenging in mechanistically ambiguous transformations. The stereoselectivity of glycosylation reactions is influenced by at least eleven factors across four chemical participants and ...
Sourav, Chatterjee, Peter H., Seeberger, Kerry, Gilmore, Soo-Yeon, Moon   +3 more
core   +1 more source