Results 21 to 30 of about 30,863 (282)
Predicting glycosylation stereoselectivity using machine learning [PDF]
, 2021 Predicting the stereochemical outcome of chemical reactions is challenging in mechanistically ambiguous transformations. The stereoselectivity of glycosylation reactions is influenced by at least eleven factors across four chemical participants and ...
Gilmore, Kerry +7 more
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Stereoselectivity in Drug Membrane Transport by Solute Carriers (SLCs) [PDF]
, 2023 Deutsche Forschungsgemeinschaft (DFG - project number 437446827)About 50% of all small molecule drugs are racemic mixtures of usually two stereoisomers.
Gebauer, Lukas
core +1 more source
Stereoselective Toxicokinetic and Distribution Study on the Hexaconazole Enantiomers in Mice
Toxics, 2023 Hexaconazole (Hex) has been widely used in agricultural products, and its residues may pose a potential risk to human health. However, the metabolic behavior of Hex enantiomers in mammal organisms is still unknown, which is important for evaluating the ...
Guofei Luo +3 more
doaj +1 more source
, 2021 International audienceAryl- and hetaryl-substituted acetylenes undergo regio- and stereoselective silylzincation by reaction with [(Me3Si)3Si]2Zn in the presence of Et2Zn (10–110 mol%) as additive.
Martin Oestreich +23 more
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Synthesis of Polysubstituted Ferrocenesulfoxides
Molecules, 2022 The purpose of the study is to design synthetic methodologies, especially directed deprotometalation using polar organometallic reagents, to access polysubstituted ferrocenesulfoxides.
Min Wen +6 more
doaj +1 more source
Molecules, 2022 The multicomponent reaction of aldehydes, cyano-containing C-H acids, esters of 3-oxocarboxylic acid and ammonium acetate led to unexpected results.
Anatoly N. Vereshchagin +4 more
doaj +1 more source
Revisiting the Stereoselectivity in Organoborane Rearrangement [PDF]
, 2022 Hydroboration of 1,2-dimethylcyclohexene (A) and successive rearrangements yield not only tertiary alkylboranes but also primary and secondary ones. In addition, nontypical anti-addition products are detected, whose formation mechanism is not apparent ...
Gabriel, Merino +5 more
core +2 more sources
Membranes, 2022 The mechanisms of stereoselectivity of the interaction of chiral drugs with active sites of enzymes and cell receptors attract significant attention.
Anna V. Mastova +2 more
doaj +1 more source
Intramolecular Diels-Alder reactions of cycloalkenones: stereoselectivity, Lewis acid acceleration, and halogen substituent effects. [PDF]
, 2014 The intramolecular Diels-Alder reactions of cycloalkenones and terminal dienes occur with high endo stereoselectivity, both thermally and under Lewis-acidic conditions.
Danishefsky, Samuel J +8 more
core +1 more source
Journal of Pharmaceutical Analysis, 2011 The protein binding of non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac with human serum albumin (HSA) was investigated using indirect chiral high performance liquid chromatography (HPLC) and ultrafiltration techniques. S-(â)-
Chang-Chuan Guo +5 more
doaj +1 more source