Results 41 to 50 of about 30,863 (282)

Synthesis and 1,3-Dipolar Cycloaddition Reactions of Chiral Maleimides

open access: yesMolecules, 1997
New routes to the synthesis of various novel chiral maleimides are described. The oxabicyclic anhydride 2 readily available exo-Diels-Alder adduct of furan and maleic anhydride was used as a vehicle, which in turn reacted with hydrochlorides of amino ...
Lubor Fisera, Vladimir Ondrus
doaj   +1 more source

Recent Advances of Pharmaceutical Process Chemistry and Its Innovation in China: Part 1

open access: yesPharmaceutical Fronts, 2020
This review article summarizes recent developments and innovations in China's pharmaceutical process chemistry over the last several decades. Case studies of dozens of blockbuster drug processes are presented, including bulk drugs, such as the over-the ...
Pei Tang   +5 more
doaj   +1 more source

Radical synthesis of biaryls and dihydrobiaryls: Controlling stereoselectivity in rhamnopyranosylation.

open access: yes, 2007
Radical synthesis of biaryls and dihydrobiaryls: Controlling stereoselectivity in ...
Miteshkumar. Patel (7977485)
core   +6 more sources

Stereoselectivity in Aldol Reactions of Chiral N-Acyl Selones

open access: yes, 2016
Stereoselectivity in Aldol Reactions of Chiral N-Acyl ...
Ruilian Wu (1549717)   +5 more
core   +4 more sources

The Origin of Stereoselectivity in the Hydrogenation of Oximes Catalyzed by Iridium Complexes: A DFT Mechanistic Study

open access: yesMolecules, 2022
Herein the reaction mechanism and the origin of stereoselectivity of asymmetric hydrogenation of oximes to hydroxylamines catalyzed by the cyclometalated iridium (III) complexes with chiral substituted single cyclopentadienyl ligands (Ir catalysts A1 and
Qaim Ali   +6 more
doaj   +1 more source

Development of an organo-and enzyme-catalysed cascade reaction [PDF]

open access: yes, 2010
This thesis describes the development of a novel one-pot reaction (Scheme 1). The reaction combines organo- and enzyme-catalysis in an aldol/aldol cascade for the first time.
Kinnell, Angela Dawn
core   +3 more sources

Synthesis of Glycosides of Glucuronic, Galacturonic and Mannuronic Acids: An Overview

open access: yesMolecules, 2011
Uronic acids are carbohydrates present in relevant biologically active compounds. Most of the latter are glycosides or oligosaccharides linked by their anomeric carbon, so their synthesis requires glycoside-bond formation. The activation of this anomeric
José Kovensky, Anne Wadouachi
doaj   +1 more source

Implications of Pharmacokinetic Potentials of Pioglitazone Enantiomers in Rat Plasma Mediated through Glucose Uptake Assay

open access: yesMolecules, 2023
Pioglitazone, a PPAR-gamma activator used to diagnose hyperglycemia, was studied for its stereoselective deposition and active enantiomers in female albino Wistar rats.
Tatineni Spandana   +8 more
doaj   +1 more source

Application of Chiral Transfer Reagents to Improve Stereoselectivity and Yields in the Synthesis of the Anti-Tuberculosis Drug Bedaquiline [PDF]

open access: yes, 2023
Bedaquiline (BDQ) is an important drug for treating multidrug-resistant tuberculosis (MDR-TB), a worldwide disease that causes more than 1.6 million deaths yearly.
Gopal, Sirasani   +14 more
core   +2 more sources

Mechanistic study of stereoselectivity in azoalkane denitrogenations

open access: yes, 2017
Since 1965, the stereoselectivity in azoalkane denitrogenation has attracted much attention in both synthetic organic chemistry and physical organic chemistry.
Manabu Abe, Sayaka Hatano
core   +1 more source

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