Results 51 to 60 of about 30,863 (282)
Probing stereoselectivity with carbohydrates [PDF]
, 1993 This thesis describes the use of carbohydrates to probe the effects of oxygenated substituents on the stereoselectivity of free radical and osmium tetroxide dihydroxylation reactions.
Gajee, Roohi
core +1 more source
Stereoselectivity of BChE and AChE.
, 2018 Stereoselectivity of BChE and AChE.
Tamara Šmidlehner (5824283) +5 more
core +1 more source
The Stereoselectivity of Drug Action [PDF]
Pharmacology & Toxicology, 1989 Pharmacologists and toxicologists are in the midst of demonstrating the importance of spatial (three-dimensional) molecular features in the functions of biological systems and in the therapeutic actions and side effects of drugs. Recent findings indicate that spatial features in a variety of biologically active molecules play a decisive role in many ...
openaire +2 more sources
Stereoselective arene formation [PDF]
Chemical Society Reviews, 2018 The common perception of arenes as flat and symmetric entities is juxtaposed to the counterintuitive circumstance that stereoselective arene formation offers a means to prepare an exceptional range of chiral aromatic structures in isomerically enriched form.
Achim Link, Christof Sparr
openaire +3 more sources
Engineering Metal‐Pocket Cooperativity in Single‐Atom COF Nanozymes for Selective Cascade Catalysis
Advanced Materials, EarlyView.A multilevel programming strategy is developed to engineer single‐atom COF nanozymes with tunable metal centers and chiral pockets inspired by heme–pocket cooperativity. This approach enables controlled metal–pocket interplay for asymmetric cascade catalysis, delivering high activity, selectivity, and recyclability in an asymmetric oxidation–aldol ...
Ziping Li +7 more
wiley +1 more source
Modular and Stereoselective Synthesis of Cyclobutane β‐Amino Alcohols
Angewandte Chemie, EarlyView.Late‐stage functionalization and photoisomerization of 1,2‐azaborine leads to a general strategy for the synthesis of diversely substituted cyclobutane β‐amino alcohols. The relative stereochemistry of the resulting products is unambiguously defined by the stereospecific and stereoselective nature of the photoisomerization‐hydrogenation‐oxidation ...
Xinyu Yang +3 more
wiley +2 more sources
Advanced Science, EarlyView.L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen +17 more
wiley +1 more source
Angewandte Chemie, EarlyView.Mixed MtaABC/MtgABC methyltransferase systems were developed for non‐native thiol and aniline methylation using the unactivated methyl donors methanol and glycine betaine. The platform enabled site‐selective and enantioselective methylation with turnover number up to 6000, representing the first enantioselective non‐native catalysis by cobamide ...
Amardeep Kumar +3 more
wiley +2 more sources
Pd‐Catalyzed Asymmetric Dearomative Heck/Tsuji‐Trost Difunctionalization of Naphthalenes
Advanced Science, EarlyView.We have developed a palladium‐catalyzed asymmetric dearomative Heck/Tsuji‐Trost 1,4‐difunctionalization reaction of naphthalenes, affording 4‐aminospirocyclohexene oxindole products bearing two remote chiral centers. Through the effect of the newly designed chiral sulfinamide phosphine ligand with large steric hindrance, side reactions are inhibited ...
Long‐Ling Ma +3 more
wiley +1 more source
Angewandte Chemie, EarlyView.Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang +1 more
wiley +2 more sources