Results 31 to 40 of about 16,646 (254)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Sex-differences of face coding: evidence from larger right hemispheric M170 in men and dipole source modelling. [PDF]

open access: yesPLoS ONE, 2013
The processing of faces relies on a specialized neural system comprising bilateral cortical structures with a dominance of the right hemisphere.
Hannes O Tiedt   +4 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Exploring decoy effects on computerized task preferences in rhesus monkeys (Macaca mulatta).

open access: yesAnimal Behavior and Cognition, 2018
The asymmetric dominance effect or decoy effect emerges when a third inferior option is introduced to a choice set. The decoy option, although typically not chosen, impacts relative preference for the original two options.
Audrey E. Parrish   +2 more
doaj   +1 more source

Collective strategies and cyclic dominance in asymmetric predator-prey spatial games [PDF]

open access: yesJournal of Theoretical Biology, 2017
Predators may attack isolated or grouped prey in a cooperative, collective way. Whether a gregarious behavior is advantageous to each species depends on several conditions and game theory is a useful tool to deal with such a problem. We here extend the Lett et al. (2004) to spatially distributed populations and compare the resulting behavior with their
Cazaubiel, Annette   +2 more
openaire   +3 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

The cortical microstructural basis of lateralised cognition: a review

open access: yesFrontiers in Psychology, 2014
The presence of asymmetry in the human cerebral hemispheres is detectable at both the macroscopic and microscopic scales. The expansion of cortical surface during development and across evolutionary time is largely due to the proliferation and spacing ...
Steven A. Chance
doaj   +1 more source

Dominant role of the asymmetric ring current in producing the stormtime Dst* [PDF]

open access: yesJournal of Geophysical Research: Space Physics, 2001
Three storms are examined to determine the contribution to the Dst* index from the symmetric and asymmetric (partial) components of the ring current. The storms (September 24–25, 1998, October 18–19, 1998, and May 14–15, 1997) all have a similar solar wind trigger (an initial shock followed by a coronal mass ejection with southward interplanetary ...
Liemohn, M.W.   +6 more
openaire   +1 more source

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