Results 61 to 70 of about 360,965 (150)
From Risk Perception to Action: The Behavioral Forces Shaping Disaster Preparedness
Abstract The study examines the behavioral forces spanning cognitive, social, and environmental determinants that transform disaster risk perception into tangible preparedness actions. The case study at hand focuses on Bucharest, the European capital with the highest seismic risk.
I. Armaş, D. Dobre, A. C. Albulescu
wiley +1 more source
AT1 receptor agonistic antibodies, hypertension, and preeclampsia
Immunologic mechanisms and putatively circulating mediators of preeclampsia are not a new idea, but are nevertheless compelling. Here we review studies relating to the role of agonistic antibodies that bind the second extracellular loop of the ...
Homuth, V. +13 more
core +1 more source
ABSTRACT By preserving molecular information inherited from the source cell, extracellular vesicles (EVs) can serve as biomarkers for tissue health or disease, paving the way for liquid biopsy applications. The enrichment of tissue‐specific EVs (TS‐EVs) from human biofluids can be challenging due to technical and methodological limitations.
Biancamaria Pierri +11 more
wiley +1 more source
Background Conflicting results have been reported regarding the association of gene polymorphisms in the renin-angiotensin system (RAS) with different aspects of coronary artery disease (CAD), such as myocardial infarction, neointimal hyperplasia or ...
Helbecque Nicole +5 more
doaj +1 more source
Atherosclerotic Cardiovascular Disease and Cancer
ABSTRACT Atherosclerotic cardiovascular disease (ASCVD) and cancer are increasingly recognized as interconnected diseases linked by shared immune mechanisms rather than merely overlapping risk factors. Common exposures such as smoking, obesity, diabetes, and dyslipidemia, together with aging and clonal hematopoiesis of indeterminate potential (CHIP ...
Anaïs Amend +4 more
wiley +1 more source
ABSTRACT Statins, widely prescribed for cardiovascular prevention, have emerged as potential disease‐modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, oxidative stress, and protein aggregation.
Luigi Maria Chiatto +7 more
wiley +1 more source
IS39, a novel non‐peptide PKR1 agonist, confers cardioprotection against doxorubicin‐induced toxicity. IS39 activates PKR1‐mediated pro‐survival signalling in cardiomyocytes, reducing reactive oxygen species (ROS), DNA damage and fibrosis markers. In vivo, IS39 preserves cardiac geometry and function in mice exposed to chronic doxorubicin challenge ...
Anais Audebrand +8 more
wiley +1 more source
RESUMO OBJETIVO:Avaliar a associação do polimorfismo A1166C do gene do receptor AT1 da angiotensina II (AT1R) com o infarto agudo do miocárdio e a severidade da doença arterial coronariana.
Messias Antônio de Araújo +5 more
doaj +1 more source
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists elicit cardiovascular and renal protection. In humans, GLP‐1 reduces plasma angiotensin II (ANGII) and increases renal perfusion, leading to increased natriuresis. The mechanisms underlying suppression of ANGII remain unclear but may involve ACE2 activation and/or a decrease in angiotensinogen.
Ali Asmar +4 more
wiley +1 more source

