Results 41 to 50 of about 360,965 (150)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease
Advanced Science, EarlyView.This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li +11 more
wiley +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT This study examines how firms secure legitimacy in markets where faith‐based expectations and environmental responsibility intersect, focusing on halal–green cosmetics among Muslim women. It conceptualises halal trust and green trust as parallel legitimacy pathways reflecting faith‐based legitimacy and environmental credibility, respectively ...
Dwi Suhartanto +4 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT The plant‐derived specialized metabolite montbretin A (MbA) is under development as an improved treatment for Type 2 diabetes, a worldwide epidemic. MbA is an acylated flavonol glycoside so far only found in small amounts in montbretia (Crocosmia × crocosmiiflora) corms.
Charlotte Hijmans +4 more
wiley +1 more source
, 2009 Agonistic autoantibodies to the angiotensin II type I receptor (AT1-AA) and endothelin -1 (ET-1) are suggested to be important links between placental ischemia and hypertension during preeclampsia.
Ray, L.F. +11 more
core +1 more source
Hypertension in response to IL-6 during pregnancy: role of AT1-receptor activation [PDF]
, 2011 BACKGROUND: Increases in interleukin 6 (IL-6) and agonistic autoantibodies to the angiotensin II type 1 receptor (AT1-AA) are proposed to be important links between placental ischemia and hypertension in preeclampsia.
Ray, L.F. +6 more
core +1 more source
Biology of Sex Differences, 2019 Background Placental ischemia and hypertension, characteristic features of preeclampsia, are associated with impaired cerebral blood flow (CBF) autoregulation and cerebral edema.
Junie P. Warrington +10 more
doaj +1 more source
Experimental Physiology, EarlyView.Abstract The two‐kidney, one‐clip (2K1C) model produces renovascular hypertension. The effects on the clipped kidney (CK) are well described, while the non‐clipped kidney (NCK) is used as a model to evaluate the effects of high blood pressure. Although most of these effects have been described at later stages of 2K1C hypertension, it remains unclear ...
Pilar Cárdenas +11 more
wiley +1 more source
Effect of prenatal AT1-AA exposure on LV cross-sectional area of myocardial cells.
, 2013 Hearts were obtained from 45-day-old rats exposed to either saline or AT1-AA before birth from day 13 and 14 of gestational age. (A) Hematoxylin and eosin (H&E)-stained histological sections of hearts (bar, 3 mm); (B) Light-microscopic (400×) examination
Xiaofang Wang (163746) +6 more
core +1 more source
ChemMedChem, Volume 21, Issue 17, 14 September 2026.A novel series of candidate AT1 receptor antagonists based on oxadiazolone‐triazole scaffolds was designed and synthesized. Most compounds reduced angiotensin II‐induced vascular contraction in an initial biological screening, with compound 7f emerging as the most active derivative.
Larissa F. L. Ferreira +5 more
wiley +1 more source