Results 11 to 20 of about 141,698 (289)
Spatial and single-nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers. [PDF]
Mol OncolMatched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Tourneur A +11 more
europepmc +2 more sources
ANXA2<sup>+</sup> Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non-Homologous End-Joining Repair. [PDF]
Adv Sci (Weinh)ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Su S, Xiong Y, Liang Y, Min X, Dai D.
europepmc +2 more sources
ارزیابی آسیب پذیری لرزه ای بیمارستان های شهر یاسوج از دیدگاه پدافند غیرعامل و روش(ATC) [PDF]
پدافند غیرعامل, 2021 ارزیابی میزان خسارت، آسیب پذیری، برنامه ریزی جهت آمادگی و کاهش خطر قبل از وقوع زلزله، امری ضروری است. با توجه به واقع شدن شهر یاسوج در جایگاه پهنه بندی با خطر نسبی بالا، وقوع یک زلزله بزرگ در این شهر خسارت ها و تلفات زیادی را در بر خواهد داشت. با توجه به
مهرداد خلقی فرد +1 more
doaj
Generative knowledge-based transfer learning for few-shot health condition estimation
Complex & Intelligent Systems, 2022 In the field of high-end manufacturing, it is valuable to study few-shot health condition estimation. Although transfer learning and other methods have effectively improved the ability of few-shot learning, they still cannot solve the lack of prior ...
Weijie Kang, Jiyang Xiao, Junjie Xue
doaj +1 more source
Environmental Advances, 2021 Perfluorooctanoic acid (PFOA) is a prevalent, persistent organic pollutant (POP) in the environment. The potential toxic impacts of PFOA on human and ecological health is becoming an increasing concern worldwide.
Tanmoy Sana +4 more
doaj +1 more source
Comparative analysis of the consumption of antihistamines for systemic use in the Republic of Serbia and Nordic countries in the period 2009-2019 [PDF]
Hospital Pharmacology, 2023 Introduction: According to the ATC system of drug classification, group R06 includes H1 antihistamines for systemic use, which are divided into drug groups of the 1st and 2nd generation. Aim: Since there are no national guidelines in Serbia, for treating
Vuković Milana M. +8 more
doaj
Design implications for teamwork in ATC [PDF]
Cognition, Technology & Work, 2019 In air trafc control (ATC), teamwork is a key component among air trafc control operators (ATCOs) to safely direct the aircraft through the sky and on the ground.
Åsa Svensson +2 more
openaire +3 more sources
Environmental Challenges, 2023 Perfluorobutanoic acid (PFBA) is ubiquitous in the environment, and its concentrations are likely to increase with time due to its usage as a substitute for the restricted long-chain per- and polyfluoroalkyl substances (PFAS). Consequently, concerns have
Tanmoy Sana +3 more
doaj +1 more source
Molecules, 2022 Sustainability evaluation of wastewater treatment helps to reduce greenhouse gas emissions, as it emphasizes the development of green technologies and optimum resource use rather than the end-of-pipe treatment.
Kuppan Praveen +3 more
doaj +1 more source
npj Clean Water, 2023 The circular bioeconomy framework addresses the global transition toward resource-efficient and low-carbon economies. The use of microalgae in sustainable circular bioeconomy largely suffers from energy consumption and underutilization of residual ...
Praveen Kuppan +3 more
doaj +1 more source