Results 1 to 10 of about 1,268,897 (251)

Integrated Network Toxicology and Metabolomics Reveal the Reproductive Toxicity Mechanisms of Alkaloid-Enriched Fractions in Tripterygium Glycosides Tablets [PDF]

open access: yesToxins
Tripterygium glycoside tablets (TGT), a representative formulation derived from Tripterygium wilfordii Hook F, have limited clinical application due to adverse reproductive toxicity.
Caiyao Han   +8 more
doaj   +2 more sources

Promoting Drp1-Mediated Mitochondrial Division in Nickel Nanoparticles-Induced Reproductive Toxicity in GC-2 Cells [PDF]

open access: yesNanomaterials
Male reproductive disorders and declining fertility rates play an important role in birth rates, and their impact on future populations makes them one of the most serious public health issues of this century.
Liya Qiao   +5 more
doaj   +2 more sources

Machine learning models for rat multigeneration reproductive toxicity prediction

open access: yesFrontiers in Pharmacology, 2022
Reproductive toxicity is one of the prominent endpoints in the risk assessment of environmental and industrial chemicals. Due to the complexity of the reproductive system, traditional reproductive toxicity testing in animals, especially guideline ...
Jie Liu   +6 more
doaj   +1 more source

Effects of Decamethylcyclopentasiloxane on Reproductive Systems in Female Rats

open access: yesToxics, 2023
The female reproductive system becomes fertile through the action of hormones involved in the hypothalamic-pituitary-ovarian axis. On the other hand, estrogen-like endocrine disruptors released into the environment come into contact with humans by ...
Jimin Lee   +4 more
doaj   +1 more source

A review of the reproductive toxicity of environmental contaminants in Caenorhabditis elegans

open access: yesHygiene and Environmental Health Advances, 2022
The release of several environmental pollutants poses a potential threat to the several ecosystems and humans. Reproductive toxicity represents one of the most significant toxic effects of environmental contaminants.
Yunjiang Yu   +8 more
doaj   +1 more source

Palliative effects of metformin on testicular damage induced by triptolide in male rats

open access: yesEcotoxicology and Environmental Safety, 2021
As a widely existing traditional Chinese medicine component, TP (triptolide) has serious reproductive toxicity which causes severe damage to the reproductive system and limits its application prospect. TP and MET (metformin) have shown great potential in
Ke Wang   +7 more
doaj   +1 more source

Follicular phase length has no influence on frozen-thawed embryo transfers in natural cycles

open access: yesJournal of Ovarian Research, 2020
Background Whether menstrual variability in women with regular and ovulatory cycle could affect embryo implantation remains controversial, with conflicting evidences presented in the literature.
Ying Ying   +5 more
doaj   +1 more source

Toxicological Effects of Technical Xylene Mixtures on the Female Reproductive System: A Systematic Review

open access: yesToxics, 2022
Technical xylene is a compound of massive production that is used in applications such as petrochemical and healthcare laboratories. Exposure to xylene can cause acute and chronic effects in humans and animals.
Noor Asyikin Suaidi   +4 more
doaj   +1 more source

Developmental and reproductive toxicity assessment in rats with KGC-HJ3, Korean Red Ginseng with Angelica gigas and Deer antlers

open access: yesJournal of Ginseng Research, 2019
Background: Korean Red Ginseng has been widely used in traditional oriental medicine for a prolonged period, and its pharmacological effects have been extensively investigated.
Jinsoo Lee   +9 more
doaj   +1 more source

Meiosis-mediated reproductive toxicity by fenitrothion in Caenorhabditis elegans from metabolomic perspective

open access: yesEcotoxicology and Environmental Safety, 2023
Fenitrothion (FNT), an organophosphorus insecticide, is widely detected in the living environment. The reproductive and endocrine toxicity of FNT to biological communities has been ever reported, but potential mechanism and reproductive toxicity dose ...
Weixi Li   +7 more
doaj   +1 more source

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