Results 41 to 50 of about 1,268,897 (251)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

The wild male mink as a sentinel for endocrine-disrupting chemicals and reproductive toxicity [PDF]

, 2013
Increasing evidence indicates that pollutants may affect the hormone system of humans and wildlife. These endocrine-disrupting chemicals are related to an increased risk of a variety of diseases and disorders, including adverse effects on the ...
Persson, Sara
core   +1 more source

Analyzing the impact of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) on the reproductive system using network toxicology and molecular docking

Heliyon
Growing evidence suggests that perfluorinated compounds (PFCs) contribute to reproductive toxicity, with perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) being the most extensively studied.
Liang Chen, Shanshan Liang, Jiaxin Li, Qian Li, Qingwen Sun   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Impacts of Environmental Concentrations of Nanoplastics on Zebrafish Neurobehavior and Reproductive Toxicity

Nanoplastics, as emerging environmental pollutants, can transport contaminants across marine environments, polluting pristine ecosystems and being ingested by marine organisms.
Jinlong Zhao, Liushuo Jia, Jing Ruan, Runchao Tao, Ziqing Sun, Peiye Xu, Jiaxuan He, Haiyang Yu, Tong Xi, Hao Ji, Baihui Wu, Jia Yi, Fei Teng   +12 more
core   +1 more source

Advances in Development of PM2.5-Exposed Animal Models and Their Application in Reproductive Toxicity Research

Shiyan dongwu yu bijiao yixue
Atmospheric fine particulate matter (particulate matter 2.5,PM2.5) is a major component of haze, and its potential hazards to human reproductive health have garnered widespread attention.
TIAN Fang, PAN Bin, SHI Jiayi, XU Yanyi, LI Weihua   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Assisted reproductive technology in the USA: is more regulation needed? [PDF]

, 2014
The regulation of assisted reproductive technologies is a contested area. Some jurisdictions, such as the UK and a number of Australian states, have comprehensive regulation of most aspects of assisted reproductive technologies; others, such as the USA ...
Frith, Lucy; id_orcid, Blyth, Eric, Frith, Lucy   +2 more
core   +1 more source

A high throughput screening system for predicting chemically-induced reproductive organ deformities

, 2022
S.95-103There is a great need for alternative testing methods for reproductive toxicants that are practical, fast, cost-effective and easy to interpret.
Buist, Harrie E., Vugt-Lussenburg, Barbara van, Kroese, Dinant E., Man, Hai-yen, Pieterse, Bart, Lewin, Geertje, Wolterbeek, Andre P.M., Rorije, Emiel, Linden, Sander C. van der, Piersma, Aldert H., Mangelsdorf, Inge, Burg, Bart van der   +11 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source