Results 61 to 70 of about 1,268,897 (251)

The toxicity of perfluoroalkyl acids in zebrafish (Danio rerio) [PDF]

, 2013
Perfluoroalkyl acids (PFAAs) are globally distributed synthetic chemicals. Their unique properties make them widely used, in industry and elsewhere. These are a group of compounds with varying carbon chain lengths and functional groups.
Ul Haq, Mazhar
core   +1 more source

Reproductive toxicity and related mechanisms of micro(nano)plastics in terrestrial mammals: Review of current evidence

Ecotoxicology and Environmental Safety
Micro(nano)plastics (MNPs) have been detected in various ecological environments and are widely used due to their stable properties, raising widespread concern about their potential human reproductive toxicity.
Yangyang Peng, Qi He
doaj   +1 more source

Reproductive toxicity of fluoroquinolones in birds

BMC Veterinary Research, 2019
Background While commercial poultry and captive birds are exposed to antimicrobials through direct medication, environmental pollution may result in contamination of wild birds.
Hana Hruba, Ehdaa Eltayeb Eltigani Abdelsalam, Nikolay Anisimov, Hana Bandouchova, Barbora Havelkova, Tomas Heger, Miroslava Kanova, Veronika Kovacova, Monika Nemcova, Vladimir Piacek, Jana Sedlackova, Frantisek Vitula, Jiri Pikula   +12 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Modulating Effects of L-Arginine and Tribulus terrestris Extract on Fipronil-Induced Interference in the Male Reproductive System of Rats: Antioxidant Potential, Androgen Receptors, and Nitric Oxide Synthase Interplay

The protective potentials of Tribulus terrestris (TT) and L-arginine (L-Arg) against reproductive toxicity induced by fipronil (FPN) in male rats were investigated. A total of 36 male rats were allocated into six groups: control, TT, L-Arg, FPN, FPN + TT,
Ahmed A. Bakhashwain, Noran M. Tawfik, Ibrahim E. Helal, Heba M. A. Abdelrazek, Hatim A. Al-Abbadi, Menna Allah I. El-Menyawy, Heba N. Gad EL-Hak, Wafaa K. Teleb, Doaa H. Elsayed, Eman A. Ahmed   +9 more
core   +1 more source

Gold Nanoclusters Inhibit the Male Reproductive Toxicity of Cu2+

, 2021
An increasing number of environmental pollutants cause adverse reproductive health effects, such as sperm quantity and quality decreasing, subfertility, or infertility, changing the birth sex ratio.
Shengnan Gong, Fei Sun, Shiyao Zhu (1986070), Shiyao Zhu, Pengfei Wu, Shengnan Gong (7400528), Yingying Huang, Wenqing Li, Fei Sun (102854), Yingying Huang (430953), Pengfei Wu (3200082), Wenqing Li (1421971)   +11 more
core   +1 more source

Potential adverse effects of nanoparticles on the reproductive system

International Journal of Nanomedicine, 2018
Ruolan Wang,1 Bin Song,2 Junrong Wu,1 Yanli Zhang,1 Aijie Chen,1 Longquan Shao1,3 1Nanfang Hospital, Southern Medical University, Guangzhou 510515, China; 2Guizhou Provincial People’s Hospital, Guiyang 550002, China; 3Guangdong Provincial Key ...
Wang R, Song B, Wu J, Zhang Y, Chen A, Shao LQ   +5 more
doaj  

Nanoplastics and chain-length-dependent PFCs disrupt reproductive endocrinology by targeting the PKC - GnRH signaling axis

Ecotoxicology and Environmental Safety
Nanoplastics (NPs) and microplastics (MPs) are widespread in aquatic ecosystems and frequently co-occurred with perfluorinated compounds (PFCs), yet their combined toxic effects remain poorly understood.
Xi Li, Yuying Fang, Jinxi Song, Haichao Sha, Le Zhang, Qi Li   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Exploring the potential protective role of anthocyanins in mitigating micro/nanoplastic-induced reproductive toxicity: A steroid receptor perspective

Journal of Pharmaceutical Analysis
Microplastics and nanoplastics (MPs/NPs) are ubiquitous environmental pollutants that act as endocrine-disrupting chemicals (EDCs), raising significant concerns about their impact on human health.
Jiaojiao Zhang, Wenyi Liu, Fuqiang Cui, Marjukka Kolehmainen, Jing Chen, Lei Zhang, Iman Zarei   +6 more
doaj   +1 more source