Results 41 to 50 of about 812 (121)

Regional electrical differences and arrhythmia in the rat atria: Role of sympathetic nerve distribution and function

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Atrial fibrillation commonly develops in the left atrium and pulmonary veins (PVs), and can be triggered by sympathetic nerve activity. Here, we examined regional atrial differences in sympathetic nerve distribution and function in the rat.
James Saleeb‐Mousa   +6 more
wiley   +1 more source

Effect of long-term antihypertensive treatment on cerebrovascular structure and function in hypertensive rats

open access: yesScientific Reports, 2023
Midlife hypertension is an important risk factor for cognitive impairment and dementia, including Alzheimer’s disease. We investigated the effects of long-term treatment with two classes of antihypertensive drugs to determine whether diverging mechanisms
Daphne M. P. Naessens   +12 more
doaj   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

open access: yesActa Ophthalmologica, Volume 104, Issue 6, Page e630-e647, September 2026.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen   +3 more
wiley   +1 more source

Exploring Cerumen as an Alternative Matrix for Drug Detection and Quantification: Method Development and Application in Clinical Samples

open access: yesDrug Testing and Analysis, Volume 18, Issue 8, Page 1065-1075, August 2026.
An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis   +5 more
wiley   +1 more source

Midterm Efficacy of SubcutAneous Implantable CardioVErter‐Defibrillator in ≤ 18 Year‐Old CHILDREN (SAVE CHILDREN‐II Registry)

open access: yesJournal of Arrhythmia, Volume 42, Issue 4, August 2026.
S‐ICD therapy demonstrated favorable mid‐term safety and efficacy in pediatric patients, with durable sensing performance and a low incidence of device‐related infection. ABSTRACT Background The subcutaneous implantable cardioverter‐defibrillator (S‐ICD) avoids transvenous leads and is a promising option for sudden cardiac death (SCD) prevention in ...
Hitoshi Mori   +76 more
wiley   +1 more source

The effectiveness of cytocardioprotection of patients with the moderately expressed post infarct dysfunction of left heart ventricle: the results of the randomization research of trimetazidine and athenolole

open access: yesБюллетень сибирской медицины, 2002
With the purpose of research of clinical efficiency of trimetazidine and atenolol and their influence on morfofunctional parameteres of left ventricle 36 men who have transferred a myocardial infarction are inspected.
V. V. Kalyuzhin   +2 more
doaj   +1 more source

Bisoprolol Treatment and Adherence in Pediatric Patients With Genotype‐Positive Long QT Syndrome

open access: yesJournal of Arrhythmia, Volume 42, Issue 4, August 2026.
LQTS is commonly treated with non‐selective beta‐blockers. In this study on Finnish pediatric patients with genotype positive LQTS1 or LQTS2, most with a Finnish founder mutation, the beta‐1‐selective bisoprolol was the most commonly used beta‐blocker with good adherence, effective heart rate control, and no cardiac events observed during follow‐up ...
Eemil Taipalus   +4 more
wiley   +1 more source

Spectrophotometric method for simultaneous estimation of atenolol in combination with losartan potassium and hydrochlorothiazide in bulk and tablet formulation

open access: yesJournal of Pharmacy and Bioallied Sciences, 2010
Aim : To develop a simple, accurate, rapid and precise UV spectrophotometric method for the estimation of atenolol in combination with losartan potassium and hydrochlorothiazide.
Sanjay Bari   +3 more
doaj   +1 more source

The effect of antihypertensive treatment on longitudinal changes in PLGF and sFlt‐1 in women with new onset hypertension in pregnancy

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 8, Page 1515-1522, August 2026.
In pregnant women with new‐onset hypertension starting antihypertensives, some achieve tight BP control within a week (Group 1‐blue line), while others respond slower (Group 2‐red line). Group 1 showed higher Log10PLGF levels, but Log10sFlt‐1 did not differ between groups. Over time, Log10PLGF declined in both groups, while Log10sFlt‐1 remained stable.
Edward Tyrell   +4 more
wiley   +1 more source

The effect of apixaban on the pharmacokinetics of digoxin and atenolol in healthy subjects

open access: yesClinical Pharmacology: Advances and Applications, 2017
Charles Frost,1 Yan Song,1 Zhigang Yu,2 Jessie Wang,3 Lois S Lee,4 Alan Schuster,5 Allyson Pollack,1 Frank LaCreta1 1Exploratory Clinical and Translational Research, Bristol-Myers Squibb, Princeton, NJ, USA; 2Medical Sciences, Amgen Asia R&D Center ...
Frost C   +7 more
doaj  

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