Results 31 to 40 of about 180,953 (150)

Treatment of severe aplastic anemia with a combination of horse antithymocyte globulin and cyclosporine, with or without sirolimus: a prospective randomized study

Haematologica, 2009
Background We hypothesized that the addition of sirolimus to standard horse antithymocyte globulin (h-ATG) and cyclosporine (CsA) would improve response rates in severe aplastic anemia, due to its complementary and synergistic properties to cyclosporine ...
Phillip Scheinberg, Colin O. Wu, Olga Nunez, Priscila Scheinberg, Carol Boss, Elaine M. Sloand, Neal S. Young   +6 more
doaj   +1 more source

Molecular Mechanisms of ATG-9 Localization and Function in Neurons [PDF]

, 2022
Autophagy is a cellular degradation pathway essential for neuronal health andfunction. Autophagosome biogenesis occurs at synapses, is locally regulated and increases in response to neuronal activity.
Yang, Sisi
core   +1 more source

Metamaterial-based Luneburg Lens for RF Applications Using Additive Manufacturing

Journal of Telecommunications and Information Technology
This article takes a detailed look at modeling, simulating, calculating, and fabricating a Luneburg lens using a single material and advanced 3D printing technology.
Emma Sadoyan, Mark Mnatsakanyan, Suren Eyramjyan   +2 more
doaj   +1 more source

Anti Thymocyte Globulin-Based Treatment for Acquired Bone Marrow Failure in Adults

Cells, 2021
Idiopathic acquired aplastic anemia can be successfully treated with Anti Thymocyte Globulin (ATG)-based immune suppressive therapy and is therefore considered a T cell-mediated auto immune disease.
Jennifer M.-L. Tjon, Saskia M. C. Langemeijer, Constantijn J. M. Halkes   +2 more
doaj   +1 more source

Purification technology design, biochemical and immunological characteristics of the recombinant chimeric antigen for evaluation of T cell immunity against coronavirus infection

Медицинская иммунология
Diagnosis of specific T cell immunity to the antigenic determinants of SARS-CoV-2 in patients seems to be an increasingly important task due to accumulation of data about the role of T cell immune response in course of coronavirus infection and clearance
V. V. Kopat, A. A. Riabchenkova, E. L. Chirak, E. R. Chirak, A. I. Saenko, I. V. Kudryavtsev, A. S. Trulioff, T. V. Savin, E. V. Zueva, A. S. Simbirtsev, A. A. Totolyan, I. V. Dukhovlinov   +11 more
doaj   +1 more source

Arctigenin Suppressed Epithelial-Mesenchymal Transition Through Wnt3a/β-Catenin Pathway in PQ-Induced Pulmonary Fibrosis

Frontiers in Pharmacology, 2020
Arctigenin (ATG), a major bioactive substance of Fructus Arctii, counters renal fibrosis; however, whether it protects against paraquat (PQ)-induced lung fibrosis remains unknown.
Fei Gao, Fei Gao, Fei Gao, Yun Zhang, Zhizhou Yang, Mengmeng Wang, Zhiyi Zhou, Wei Zhang, Yi Ren, Xiaoqin Han, Mei Wei, Zhaorui Sun, Shinan Nie, Shinan Nie   +13 more
doaj   +1 more source

Research advances of cell autophagy in focal segmental glomerulosclerosis

Linchuang shenzangbing zazhi
As a clinical pathological syndrome, focal segmental glomerulosclerosis （FSGS） is characterized by focal glomerulosclerosis, disappearance of podocyte processes and massive proteinuria. Current researches have confirmed that foot cell injury is a central
Min Zhang, Yan Mi, Cai-li Wang
doaj   +1 more source

ATG proteins: Are we always looking at autophagy? [PDF]

, 2016
Autophagy is an intracellular degradation pathway that is regulated by the autophagy-related (ATG) proteins. For a long time it has been thought that ATG proteins were exclusively required for autophagy, but recent experimental evidence has revealed that
Mauthe, Mario, Reggiori, Fulvio
core   +1 more source

Partial SAA patients benefit from delayed response of IST

Frontiers in Immunology, 2023
IntroductionSevere aplastic anemia(SAA)is a severe disease characterized by immune-mediated bone marrow failure and pancytopenia. Immunosuppressive therapy (ATG plus CsA, IST) is the standard treatment for patients who are not suitable for allogeneic ...
Ting Wang, Chaomeng Wang, Chunyan Liu, Zonghong Shao, Rong Fu   +4 more
doaj   +1 more source

juhjeong/ATG: Ate-Grab

, 2022
This is the repository which contains the code that was used to generate the results and figures of the "PD-L1-directed PlGF/VEGF blockade synergizes with chemotherapy by targeting CD141+ cancer-associated fibroblasts in pancreatic cancer ...
Juhee
core   +1 more source