Results 61 to 70 of about 180,953 (150)

Using microbes as a key tool to unravel the mechanism of autophagy and the functions of the ATG proteins [PDF]

, 2016
The study of microbe infections has always been a very effective approach to unveil and dissect cellular pathways. Autophagy is not an exception. Although some of the breakthrough discoveries in the field were obtained using yeast, pathogens have been ...
Mauthe, Mario, Mario Mauthe, Reggiori, Fulvio, Fulvio Reggiori   +3 more
core   +2 more sources

Sensitivity analysis per first ATG–T infusion day.

, 2023
Sensitivity analysis per first ATG–T infusion day.
Leila Beltrami Moreira (15245306), Bruno Mateus de Castro (15314681), Alessandra Paz (439207), Thiago Almirante Cunha (15314684), Joice Zuckermann (15314678)   +4 more
core   +1 more source

Treatment of acute graft versus host disease with low dose-alternate day anti-thymocyte globulin

Haematologica, 2002
BACKGROUND AND OBJECTIVES: The efficacy of antithymocyte globulin (ATG) in the treatment of graft-versus-host disease (GvHD) is controversial. In the present study we report on the use of low dose ATG (thymoglobuline, Sangstat) and steroids in 28 ...
F Graziani, MT Van Lint, A Dominietto, AM Raiola, C Di Grazia, T Lamparelli, F Gualandi, S Bregante, M Fiorone, B Bruno, A Bacigalupo   +10 more
doaj  

Dual T-cell depletion with individually tailored anti-thymocyte globulin and attenuated dose of post-transplant cyclophosphamide in haploidentical peripheral stem cell transplantation

Scientific Reports
This study aimed to assess the efficacy of dual T-cell suppression using individually tailored doses of antithymocyte globulin (ATG) and attenuated dose of post-transplant cyclophosphamide (PTCy) in haploidentical hematopoietic stem cell transplantation (
Dong Hyun Kim, Dong-Yeop Shin, Youngil Koh, Inho Kim, Sung-Soo Yoon, Ja Min Byun, Junshik Hong   +6 more
doaj   +1 more source

Impact of antithymocyte globulin on outcomes of allogeneic hematopoietic cell transplantation with TBI

Blood Advances, 2019
: The impact of the use of antithymocyte globulin (ATG) following a total body irradiation (TBI)–based myeloablative conditioning regimen has been poorly explored.
Arnon Nagler, Myriam Labopin, Bhagirathbhai Dholaria, Riitta Niittyvuopio, Johan Maertens, Xavier Poiré, Jan Cornelissen, Péter Reményi, Jean Henri Bourhis, Yves Beguin, Ram Malladi, Tessa Kerre, Wilfried Schroyens, Bipin N. Savani, Mohamad Mohty   +14 more
doaj   +1 more source

BEAM/ATG or cyclophosphamide/ATG as conditioning regimen in autologous haemopoietic stem cell transplantation for multiple sclerosis: a retrospective analysis of the EBMT autoimmune diseases working party [PDF]

Multiple Sclerosis (MS) is the most frequent autoimmune disease (AD) treated with autologous hematopoietic stem cell transplantation (HSCT). There are no prospective trials comparing the most used conditioning regimens, BEAM/Anti-thymocyte globulin (ATG)
Greco, R., Sanz, Jaime, Badoglio, M., Nozzoli, C., Varaldo, Riccardo, Greco, Raffaella, Smilowski, Marek, Withers, Barbara, Burman, J., Massey, Jennifer, Roldan, Elisa, Alexander, Tobias, Sormani, M.P., Saccardi, R., Alexander, T., Kazmi, M., Mariottini, A., Carlson, Kristina, Signori, A., Burman, Joachim, Carlson, K., Kazmi, Majid, Gil-Perotin, Sara, Roldan, E., Gabriel, I., Snowden, J.A., Mariottini, Alice, Smilowski, M., Sormani, Maria Pia, Inglese, M., Badoglio, Manuela, Gabriel, Ian, Helbig, Grzegorz, Massey, J., Gil-Perotin, S., Muraro, Paolo A., Helbig, G., Varaldo, R., Sharrack, B., Ponzano, M., Saccardi, Riccardo, Ponzano, Marta, Sanz, J., Inglese, Matilde, Snowden, John A., Nozzoli, Chiara, Withers, B., Sharrack, Basil, Signori, Alessio, Muraro, P.A.   +49 more
core   +1 more source

Oligonucleotide subsets selection by single nucleotide resolution barcode identification

Nature Communications
Effective subset selection from complex oligonucleotide libraries is crucial for genomics, synthetic biology, and DNA data storage. The polymerase chain reaction, foundational for amplifying target subsets is limited by primer design and length for ...
Woojin Kim, Mingweon Chon, Yoonhae Koh, Hansol Choi, Eunjin Choi, Hyewon Park, Yushin Jung, Taehoon Ryu, Sunghoon Kwon, Yeongjae Choi   +9 more
doaj   +1 more source

Antithymocyte globulin therapy in chronic lung allograft dysfunction

Frontiers in Transplantation
IntroductionLung transplantation has seen strides in survival over the past few decades, though long-term survival remains poor. Chronic lung allograft dysfunction (CLAD) is a leading cause of graft failure and mortality beyond the first year.
Akhilesh Ajay Padhye, Danielle Guffey, Andres Leon-Pena, Justin Segraves, Ramiro Fernandez, Gabriel Loor, Puneet Garcha, Tianshi David Wu, Gloria Li   +8 more
doaj   +1 more source

Mechanism of Platelet Activation and Hypercoagulability by Antithymocyte Globulins (ATG)

, 2015
T cell depletion with antithymocyte globulins (ATG) can be complicated by thrombopenia and hypercoagulability. The underlying mechanism is still unclear.
Sadallah, S., Tsakiris, D., Cumpelik, A., Dickenmann, M., Zecher, D., Jin, J., Gerossier, E., Schifferli, J.A.   +7 more
core   +1 more source

ROC curves of all ATG and near-cognate classifiers derived from same test data.

, 2022
All classifiers were run on the ATG and Near-cognate RFC test datasets, and their ROC curves were superimposed. The AUROC scores of the ATG and near-cognate RFCs are 0.95 and 0.94, respectively.
Yoshifumi Sonobe (217333), Alec C. Gleason (12709783), Ghanashyam Ghadge (6321455), Raymond P. Roos (3358088), Jin Chen (130241)   +4 more
core   +1 more source