Results 71 to 80 of about 185,884 (310)

The impact of lipid-lowering medications on coronary artery plaque characteristics

American Journal of Preventive Cardiology, 2021
Atherosclerosis is the predominant cause of coronary artery disease. The last several decades have witnessed significant advances in lipid-lowering therapies, which comprise a central component of atherosclerotic cardiovascular disease prevention.
Vishnu Priya Pulipati, Francis J. Alenghat   +1 more
doaj   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Cyclic variation of the common carotid artery structure in relation to prior atherosclerotic burden and physical activity [PDF]

, 2015
Background and aims: Cardiovascular disease (CVD) accounts for the most deaths of non-communicable diseases worldwide. It begins with structural and functional changes of the arterial system commonly known as the atherosclerotic process, starting ...
Caviezel, Seraina
core   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Hypoxic and Cold Adaptation Insights from the Himalayan Marmot Genome

iScience, 2019
Summary: The Himalayan marmot (Marmota himalayana) is a hibernating mammal that inhabits the high-elevation regions of the Himalayan mountains. Here we present a draft genome of the Himalayan marmot, with a total assembly length of 2.47 Gb.
Liang Bai, Baoning Liu, Changmian Ji, Sihai Zhao, Siyu Liu, Rong Wang, Weirong Wang, Pu Yao, Xuming Li, Xiaojun Fu, Haiyan Yu, Min Liu, Fengming Han, Ning Guan, Hui Liu, Dongyuan Liu, Yuanqing Tao, Zhongdong Wang, Shunsheng Yan, Greg Florant, Michael T. Butcher, Jifeng Zhang, Hongkun Zheng, Jianglin Fan, Enqi Liu   +24 more
doaj   +1 more source

Clonal hematopoiesis and atherosclerotic cardiovascular disease: A primer. [PDF]

, 2023
Despite current standards of care, a considerable risk of atherosclerotic cardiovascular disease remains in both primary and secondary prevention. In this setting, clonal hematopoiesis driven by somatic mutations has recently emerged as a relatively ...
Fuster, Jose J., Zuriaga, María A
core   +1 more source

Hard‐Magnetic Soft Millirobots in Underactuated Systems

Advanced Robotics Research, EarlyView.
This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang, Zixuan Zhang, Bingyan Li, Junkai Wang, Hongcheng Gu   +4 more
wiley   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Factors associated with high cardiovascular risk in a primarily African American, urban HIV-infected population

SAGE Open Medicine, 2017
Objective: To determine factors associated with increased risk of developing cardiovascular disease in a high-risk patient population. Design: Cross-sectional analysis of a retrospective cohort study.
Shashwatee Bagchi, Shana AB Burrowes, Lori E Fantry, Mian B Hossain, Gemechis H Tollera, Shyamasundaran Kottilil, C David Pauza, Michael Miller, Mona Baumgarten, Robert R Redfield   +9 more
doaj   +1 more source

Aspirin in primary prevention of cardiovascular disease and cancer : a systematic review of the balance of evidence from reviews of randomized trials [PDF]

, 2013
Background: Aspirin has been recommended for primary prevention of cardiovascular disease (CVD) and cancer, but overall benefits are unclear. We aimed to use novel methods to re-evaluate the balance of benefits and harms of aspirin using evidence from
Binu Gurung, Gurung, T., Kandala Ngianga-Bakwin, Amy Grove, Gurung, Binu, Morrow, Sarah, Aileen Clarke (470453), Grove, Amy L., Tara Gurung, Kandala, Ngianga-Bakwin, Samantha Johnson (493518), Sutcliffe, P. (Paul), Connock, M., Johnson, Samantha Ann, Binu Gurung (493521), Aileen Clarke, Stranges, Saverio, Martin Connock (159426), Sarah Morrow (493522), Tara Gurung (493516), Sarah Morrow, Kandala Ngianga-Bakwin (493519), Saverio Stranges, Amy Grove (493520), Samantha Johnson, Paul Sutcliffe, Paul Sutcliffe (493515), Karoline Freeman, Martin Connock, Karoline Freeman (493517), Saverio Stranges (73786), Freeman, Karoline, Clarke, Aileen   +32 more
core   +1 more source