Results 91 to 100 of about 185,884 (310)

Waist Circumference predicting Cardiovascular Disease in Korean Men and Women

, 2010
Objective: Obesity and cardiovascular disease (CVD) are closely related and have become increasingly prevalent in Korea. Asians are more prone to obesity-related co-morbidities than Caucasians, even at lower body mass index (BMI) and/or smaller waist ...
Sun Ha Jee, Sat Byul Park
core  

Intestinal Source Control of Lipid Metabolism by Enzyme‐Probiotic Encapsulated, Spatiotemporal Crosslinked, and Small Intestine‐Adhesive Hydrogel Microspheres

Advanced Science, EarlyView.
A thiol‐modified alginate hydrogel microsphere‐encapsulated enzyme‐probiotic biohybrid (AKK‐COD) system has been developed to address the spatiotemporal delivery and colonization challenges of small intestine‐targeted probiotic for lipid metabolism regulation. The system exerts sequential functions of intragastric protection, small intestinal adhesion,
Xiaolin Wu, Weiwen Liang, Siqi He, Guangyuan Chen, Hui Zhou, Xinglong Wang, Yifei Li, Dingcai Wu, Bingna Zheng, Ruoxu Dou, Rongkang Huang   +10 more
wiley   +1 more source

Alpha-Linolenic Acid: Is It Essential to Cardiovascular Health? [PDF]

, 2010
There is a large body of scientific evidence that has been confirmed in randomized controlled trials indicating a cardioprotective effect for omega-3 fatty acids from fish.
Brouwer, I.A., Johanna M. Geleijnse, Brouwer, I.A.; id_orcid, Geleijnse, J.M., Goede, J., de, Janette de Goede, Goede, J., Ingeborg A. Brouwer, de Goede, J.   +8 more
core   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

Advanced Science, EarlyView.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An, Yunxia Zou, Wenli Wang, Zhimei Cheng, Zhuoxing Zhang, Ruwei Liu, Xiong Wang, Kunlun Huang, Fangrong Ding, Yunping Dai, Qingyong Meng, Yali Zhang   +11 more
wiley   +1 more source

Coffee consumption and coronary calcification: The Rotterdam coronary calcification study

, 2008
BACKGROUND - The role of coffee in the cardiovascular system is not yet clear. We examined the relation of coffee intake with coronary calcification in a population-based cohort.
Hofman, A. (Albert), Witteman, JCM, Matthijs Oudkerk, Vliegenthart, R. (Rozemarijn), Hofman, Albert, Albert Hofman, Hofman, Bert, Oudkerk, M. (Matthijs), Geertruida J. van Woudenbergh, van Rooij, FJA; id_orcid, Geleijnse, J.M., Vliegenthart, R (Rozemarijn), Geleijnse, J.M. (Marianne), Rooij, F.J.A. (Frank) van, Vliegenthart, R., Rozemarijn Vliegenthart, Jacqueline C.M. Witteman, Rooij, F.J.A., van, Geleijnse, Johanna M., Witteman, J.C.M. (Jacqueline), van Rooij, Frank J. A., Geleijnse, JM (Marianne), Witteman, J.C.M., Oudkerk, Matthijs; id_orcid, Johanna M. Geleijnse, Hofman, A., van Woudenbergh, Geertruida J., van Woudenbergh, G.J., Woudenbergh, G.J., van, Woudenbergh, G.J. (Geertruida) van, van Rooij, F.J.A., van Woudenbergh, GJ, Oudkerk, Matthijs, Witteman, Jacqueline C. M., Vliegenthart, Rozemarijn, Oudkerk, M., Frank J.A. van Rooij, Oudkerk, M   +37 more
core   +1 more source

Pathological Mechanism‐Inspired Biomimetic Nano‐Senotherapy for Reversing Experimental Atherosclerosis in ApoE−/− Mice

Advanced Science, EarlyView.
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian, Yanrui Yang, Qiuyu Li, Ying Hu, Qin Hu, Shasha Ran, Siyu Zhou, Xiujuan Yang, Shanshan Li, Qixiong Zhang   +9 more
wiley   +1 more source

Atherosclerotic Cardiovascular Disease Beginning in Childhood [PDF]

Korean Circulation Journal, 2010
Although the clinical manifestations of cardiovascular disease (CVD), such as myocardial infarction, stroke, and peripheral vascular disease, appear from middle age, the process of atherosclerosis can begin early in childhood. The early stage and progression of atherosclerosis in youth are influenced by risk factors that include obesity, hypertension ...
openaire   +2 more sources

Nicotine strongly activates dendritic cell-mediated adaptive immunity - potential role for progression of atherosclerotic lesions

, 2003
Background - Antigen-presenting cells (APCs) such as monocytes and dendritic cells (DCs) stimulate T-cell proliferation and activation in the course of adaptive immunity.
Dimmeler, S, Heeschen, C, Andreas M. Zeiher, Alexandra Aicher, Cooke, JP, Mariette Mohaupt, Aicher, A, Aicher, A., Christopher Heeschen, Stefanie Dimmeler, John P. Cooke, Zeiher, A.M., Heeschen, C., Dimmeler, S., Mohaupt, M, Mohaupt, M., Zeiher, AM, Cooke, J.P.   +17 more
core   +1 more source

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

Advanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng, Shiteng Cai, Jinfeng Gao, Sheng Zhao, Bohan Wei, Xueyi Weng, Zhengmin Wang, Qiaozi Wang, Qiyu Li, Chengzhi Han, Weiyan Li, Yiwen Tan, Yuyuan Fu, Meng Ji, Zheyong Huang, Yanan Song, Juying Qian, Junbo Ge   +17 more
wiley   +1 more source

Cost-effectiveness of a fixed-dose combination pill for secondary prevention of cardiovascular disease in China, India, Mexico, Nigeria, and South Africa: a modelling study

The Lancet Global Health, 2019
Summary: Background: Fewer than 25% of patients with atherosclerotic cardiovascular disease in countries of low and middle income (LMICs) use guideline-directed drugs for secondary prevention.
John K Lin, MD, Andrew E Moran, MD, Kirsten Bibbins-Domingo, MD, Bode Falase, FRCS, Andrea Pedroza Tobias, MSC, Charuta N Mandke, DOMS, Dhruv S Kazi, MD   +6 more
doaj   +1 more source