Results 101 to 110 of about 283,363 (298)

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Porphyromonas gingivalis aggravates atherosclerotic plaque instability by promoting lipid-laden macrophage necroptosis

Signal Transduction and Targeted Therapy
At advanced phases of atherosclerosis, the rupture and thrombogenesis of vulnerable plaques emerge as primary triggers for acute cardiovascular events and fatalities. Pathogenic infection such as periodontitis-associated Porphyromonas gingivalis (Pg) has
Xiaofei Huang, Mengru Xie, Yixuan Wang, Xiaofeng Lu, Feng Mei, Kaiwen Zhang, Xinlong Yang, Guangjin Chen, Ying Yin, Guangxia Feng, Wencheng Song, Nianguo Dong, Xuliang Deng, Songling Wang, Lili Chen   +14 more
doaj   +1 more source

Coronary Artery Disease and Atherosclerosis in Other Vascular Districts: Epidemiology, Risk Factors and Atherosclerotic Plaque Features

Life
Coronary artery disease (CAD) is the main cause of morbidity and death worldwide, and atherosclerosis represents the leading pathophysiological pathway responsible for CAD.
Michele Russo, Filippo Luca Gurgoglione, Alessandro Russo, Riccardo Rinaldi, Laura Torlai Triglia, Matteo Foschi, Carlo Vigna, Rocco Vergallo, Rocco Antonio Montone, Umberto Benedetto, Giampaolo Niccoli, Marco Zimarino   +11 more
doaj   +1 more source

Plaque regression and plaque stabilisation in cardiovascular diseases

Indian Journal of Endocrinology and Metabolism, 2013
Atherosclerosis is characterized by formation of plaques on the inner walls of arteries that threatens to become the leading cause of death worldwide via its sequelae of myocardial infarction and stroke.
Tarun Dave, J Ezhilan, Hardik Vasnawala, Vinod Somani   +3 more
doaj   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Chronic miR‐29 antagonism promotes favorable plaque remodeling in atherosclerotic mice

EMBO Molecular Medicine, 2016
Abnormal remodeling of atherosclerotic plaques can lead to rupture, acute myocardial infarction, and death. Enhancement of plaque extracellular matrix (ECM) may improve plaque morphology and stabilize lesions.
Victoria Ulrich, Noemi Rotllan, Elisa Araldi, Amelia Luciano, Philipp Skroblin, Mélanie Abonnenc, Paola Perrotta, Xiaoke Yin, Ashley Bauer, Kristen L Leslie, Pei Zhang, Binod Aryal, Rusty L Montgomery, Thomas Thum, Kathleen Martin, Yajaira Suarez, Manuel Mayr, Carlos Fernandez‐Hernando, William C Sessa   +18 more
doaj   +1 more source

Up-regulated expression of NHE1 and Netrin-1 in atherosclerotic plaque of ApoE-/-mice [PDF]

Jichu yixue yu linchuang, 2020
Objective To investigate whether ApoE-/- mouse atherosclerotic plaque tissue and RAW 264.7 simultaneously express sodium hydrogen exchanger 1 (NHE1) and neurite guidance factor-1 (netrin-1), and their co-localization and interaction.
YANG Hui, MO Xian-gang, WANG Lan, ZHANG Shi-yue
doaj  

Reconstruction and quantification of the carotid artery bifurcation from 3D ultrasound images [PDF]

, 2004
Three-dimensional (3-D) ultrasound is a relatively new technique, which is well suited to imaging superficial blood vessels, and potentially provides a useful, noninvasive method for generating anatomically realistic 3-D models of the peripheral ...
Thom, S A M, Hughes, AD, Hughes, A D, Barratt, D C, Humphries, K N, Thom, SAM, Ariff, BB, Ariff, B B, Barratt, DC, Humphries, KN   +9 more
core   +1 more source

Dnmt3a Mutations Limit Normal and Autoreactive CD4+ T Follicular Helper Responses and Attenuate T Cell–Driven Joint Inflammation

Arthritis &Rheumatology, EarlyView.
Objective Somatic DNMT3A mutations are the most common drivers of clonal hematopoiesis in patients with rheumatoid arthritis (RA) and have been associated with seropositive disease and increased markers of inflammation. These mutations are predominantly hypomorphic or dominant‐negative, reducing DNMT3A function.
Yunbing Shen, Sanjaykumar Boddul, Zhaojun Li, Zsolt Kasza, Marlene Schülein, Bruno Raposo, Karine Chemin, Per‐Johan Jakobsson, Alexander Espinosa, Lars Klareskog, Fredrik Wermeling   +10 more
wiley   +1 more source

Non-invasuve Coronary Atherosclerotic Plaque Imaging [PDF]

, 2023
Coronary artery disease is the leading cause of morbidity and mortality worldwide. Despite remarkable advances in the management of coronary artery disease, the prediction of adverse coronary events remains challenging.
Dey, Damini, Kwiecinski, Jacek, Williams, Michelle C; id_orcid, Berman, Daniel, Newby, David E, Dweck, Marc R, Tzolos, Evangelos, Slomka, Piotr   +7 more
core