Results 111 to 120 of about 510,573 (299)

Angiotensin II as an Inducer of Atherosclerosis: Evidence from Mouse Studies [PDF]

, 2013
Mechanisms responsible for atherosclerotic plaque development, destabilization, and rupture are still largely unknown. Angiotensin II, the main bioactive peptide of renin angiotensin system, has been shown to be critically involved in the pathogenesis of
Mazzolai, L., Pellegrin, M.
core   +1 more source

Gadolinium Enhancement in Intracranial Atherosclerotic Plaque and Ischemic Stroke: A Systematic Review and Meta‐Analysis

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2016
Background Gadolinium enhancement on high‐resolution magnetic resonance imaging (MRI) has been proposed as a marker of inflammation and instability in intracranial atherosclerotic plaque.
Ajay Gupta, H. Baradaran, Khalid Al‐Dasuqi, Ashley Knight‐Greenfield, A. Giambrone, Diana Delgado, D. Wright, Z. Teng, J. Min, B. Navi, C. Iadecola, H. Kamel   +11 more
semanticscholar   +1 more source

Atherosclerotic Plaque Rupture: Identifying the Straw That Breaks the Camel's Back.

Arteriosclerosis, Thrombosis and Vascular Biology, 2016
The idiom “the straw that breaks the camel’s back” describes scenarios where seemingly minor incidents eventuate in a sudden, unexpected, and often detrimental downfall.
Yung-Chih Chen, A. Huang, T. Kyaw, A. Bobik, K. Peter   +4 more
semanticscholar   +1 more source

Natriuretic peptide receptor-C is up-regulated in the intima of advanced carotid artery atherosclerosis [PDF]

, 2016
OBJECTIVE: Natriuretic peptide receptor-C (NPR-C/NPR-3) is a cell surface protein involved in vascular remodelling that is up-regulated in atherosclerosis. NPR-C expression has not been well characterized in human carotid artery occlusive lesions.
Abendschein, Dana R, Detering, Lisa, Harring, Scott D, Liu, Yongjian, Lu, Dongsi, Vemuri, Chandu, Woodard, Pamela K, Zayed, Mohamed A   +7 more
core   +3 more sources

Association of Lipoprotein(a) With Atherosclerotic Plaque Progression

Journal of the American College of Cardiology, 2022
Y. Kaiser, M. Daghem, E. Tzolos, M. Meah, M. Doris, A. Moss, J. Kwieciński, J. Kroon, N. Nurmohamed, P. van der Harst, P. Adamson, M. Williams, D. Dey, D. Newby, E. Stroes, K. Zheng, M. Dweck   +16 more
semanticscholar   +1 more source

Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe–/– mice

Molecular Metabolism, 2021
Objective: Interferon regulatory factor (IRF) 5 is a transcription factor known for promoting M1 type macrophage polarization in vitro. Given the central role of inflammatory macrophages in promoting atherosclerotic plaque progression, we hypothesize ...
Julia Leipner, Tsai-Sang Dederichs, Alexander von Ehr, Simon Rauterberg, Carolin Ehlert, Julian Merz, Bianca Dufner, Natalie Hoppe, Katja Krebs, Timo Heidt, Constantin von zur Muehlen, Peter Stachon, Klaus Ley, Dennis Wolf, Andreas Zirlik, Christoph Bode, Ingo Hilgendorf, Carmen Härdtner   +17 more
doaj  

Resolution of Occlusive Carotid Artery Thrombus Treated with Anticoagulation as Demonstrated on Duplex Ultrasonography. [PDF]

, 2017
BACKGROUND AND PURPOSE: While the majority of cerebral ischemic events due to carotid occlusive disease result from atherosclerotic plaque rupture, intraluminal carotid artery thrombus occasionally occurs in patients without preexisting carotid ...
Liang, John W., Stein, Laura, Weinberger, Jesse   +2 more
core   +2 more sources

Multidimensional Contribution of Matrix Metalloproteinases to Atherosclerotic Plaque Vulnerability: Multiple Mechanisms of Inhibition to Promote Stability

Journal of Vascular Research, 2016
The prevalence of atherosclerotic disease continues to increase, and despite significant reductions in major cardiovascular events with current medical interventions, an additional therapeutic window exists.
J. Ruddy, J. Ikonomidis, Jeffrey A. Jones   +2 more
semanticscholar   +1 more source

Relationship between the Levels of MMP-9, TIMP-1, and Zinc in Biological Samples of Patients with Carotid Atherosclerosis [PDF]

International Journal of Biomedicine, 2015
The aim our study was to evaluate the levels of zinc in blood serum, hair, and specimens of carotid artery atherosclerotic plaques (CAAPs) and their relationship to levels of MMP-9 and TIMP-1 in the serum of patients with stable and unstable CAAPs ...
Zakhro A. Usmanova
doaj  

Assessment of coronary artery outward remodeling in consequence of excision of epicardial adipose tissue in Ossabaw swine [PDF]

, 2017
Background Coronary artery disease (CAD) results from the buildup of cholesterol, inflammatory factors, and proliferating smooth muscle cells within a vessel wall. This plaque impedes on the vessel lumen, decreasing the space through which blood can flow,
Coderre, Kelly
core   +1 more source