Results 11 to 20 of about 154,772 (354)

Macrophage death in atherosclerosis: potential role in calcification

open access: yesFrontiers in Immunology, 2023
Cell death is an important aspect of atherosclerotic plaque development. Insufficient efferocytosis of death cells by phagocytic macrophages leads to the buildup of a necrotic core that impacts stability of the plaque.
Jaap G. Neels   +2 more
doaj   +1 more source

Ginsenoside Rb1 Enhances Plaque Stability and Inhibits Adventitial Vasa Vasorum via the Modulation of miR-33 and PEDF

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Atherosclerosis is closely associated with proliferation of the adventitial vasa vasorum, leading to the atherosclerotic plaque progression and vulnerability.
Xiaoyan Yang   +20 more
doaj   +1 more source

Effects of norepinephrine on plaque hypoxia in atherosclerotic rabbits

open access: yesFrontiers in Cardiovascular Medicine, 2023
BackgroundHypoxia plays a vital role throughout the whole process of atherosclerotic vulnerable plaque formation, which may be induced by a reduced oxygen supply.
Jia-Yu Wang   +4 more
doaj   +1 more source

The Role of Matrix Metalloproteinase-9 in Atherosclerotic Plaque Instability

open access: yesMediators of Inflammation, 2020
Matrix metalloproteinase-9 (MMP-9) belongs to the MMP family and has been widely investigated. Excessive MMP-9 expression can enhance extracellular matrix degradation and promote plaque instability.
Tiewei Li   +5 more
doaj   +1 more source

Intermedin1-53 attenuates atherosclerotic plaque vulnerability by inhibiting CHOP-mediated apoptosis and inflammasome in macrophages

open access: yesCell Death and Disease, 2021
Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has been proved to ...
Jin-Ling Ren   +9 more
doaj   +1 more source

Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque [PDF]

open access: yes, 2018
Experimental studies showed that gut-derived lipopolysaccharide (LPS) is pro-atherogenic, however, its relationship with human atherosclerosis is still to be defined.
Cammisotto, Vittoria   +11 more
core   +2 more sources

Research Progress on the Risk Factors and Outcomes of Human Carotid Atherosclerotic Plaques

open access: yesChinese Medical Journal, 2017
Objective: Atherosclerosis is an inflammatory process that results in complex lesions or plaques that protrude into the arterial lumen. Carotid atherosclerotic plaque rupture, with distal atheromatous debris embolization, causes cerebrovascular events ...
Xiang-Dong Xiong   +3 more
doaj   +1 more source

Atherosclerotic carotid plaque composition: a 3T and 7T MRI-histology correlation study [PDF]

open access: yes, 2016
Background and Purpose Carotid artery atherosclerotic plaque composition may influence plaque stability and risk of thromboembolic events, and non-invasive plaque imaging may therefore permit risk stratification for clinical management.
Condon, B.   +7 more
core   +1 more source

Comparative study on hemodynamic environments around patient-specific carotid atherosclerotic plaques with different symmetrical features

open access: yesMedicine in Novel Technology and Devices, 2021
Atherosclerotic plaque near the carotid sinus is a key risk factor for ischemic stroke. Although disturbed hemodynamic environments around atherosclerotic plaque had been investigated in many studies, the effect of their symmetrical features, especially ...
Xianghui Gong   +5 more
doaj   +1 more source

Atherosclerotic carotid plaque segmentation [PDF]

open access: yesThe 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2005
Atherosclerosis is the major cause of heart attack and stroke in the western world. In this paper we present a computerized method for segmenting the athrerosclerotic carotid plaque from ultrasound images. The method uses the blood flow image first to detect the initial contour of the plaque, and then despeckle filtering and snakes to deform the ...
Loizou, Christos P.   +4 more
openaire   +3 more sources

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