Results 11 to 20 of about 146,166 (354)

Plasma Testosterone Levels and Atherosclerotic Plaque Gene Expression in Men With Advanced Atherosclerosis

open access: yesFrontiers in Cardiovascular Medicine, 2021
Aims: Low plasma testosterone levels have been shown to predict worse outcome in men with severe atherosclerotic disease. We hypothesized that a low plasma testosterone level affects disease risk through changes in gene expression in atherosclerotic ...
Floor Groepenhoff   +9 more
doaj   +1 more source

Potential circulating biomarkers of atherosclerotic plaque vulnerability in patients in the early recovery period of atherothrombotic stroke [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2023
Despite the informative value of ultrasound examination of atherosclerotic vascular lesions, predicting­ the plaque vulnerabili­ty remains difficult. Circulating blood biomarkers could provide additional criteria that would allow better determination of ...
O. Ya. Mykhalojko, I. Ya. Mykhalojko
doaj   +1 more source

Macrophage death in atherosclerosis: potential role in calcification

open access: yesFrontiers in Immunology, 2023
Cell death is an important aspect of atherosclerotic plaque development. Insufficient efferocytosis of death cells by phagocytic macrophages leads to the buildup of a necrotic core that impacts stability of the plaque.
Jaap G. Neels   +2 more
doaj   +1 more source

Ginsenoside Rb1 Enhances Plaque Stability and Inhibits Adventitial Vasa Vasorum via the Modulation of miR-33 and PEDF

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Atherosclerosis is closely associated with proliferation of the adventitial vasa vasorum, leading to the atherosclerotic plaque progression and vulnerability.
Xiaoyan Yang   +20 more
doaj   +1 more source

Stabilization of atherosclerotic plaques: an update [PDF]

open access: yesEuropean Heart Journal, 2013
The majority of coronary thrombi (∼75%) is caused by plaque rupture .1,2 Prototype of the rupture-prone plaque contains a large, soft, lipid-rich necrotic core with a thin and inflamed fibrous cap, so-called thin-cap fibroatheroma (TCFA) ( Figure 1 ).3,4 Other common features include expansive remodelling, large plaque size, plaque haemorrhage ...
Yla-Herttuala, S.   +19 more
openaire   +8 more sources

MicroRNAs in the Atherosclerotic Plaque [PDF]

open access: yesClinical Chemistry, 2013
BACKGROUND MicroRNAs (miRNA, miR) are noncoding RNAs that regulate gene expression by hindering translation. miRNA expression profiles have been shown to differ in vivo and in vitro in many cellular processes associated with cardiovascular diseases (CVDs).
Emma Raitoharju   +2 more
openaire   +2 more sources

Atherosclerotic carotid plaque segmentation [PDF]

open access: yesThe 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2005
Atherosclerosis is the major cause of heart attack and stroke in the western world. In this paper we present a computerized method for segmenting the athrerosclerotic carotid plaque from ultrasound images. The method uses the blood flow image first to detect the initial contour of the plaque, and then despeckle filtering and snakes to deform the ...
Loizou, C.P.   +4 more
openaire   +4 more sources

Effects of norepinephrine on plaque hypoxia in atherosclerotic rabbits

open access: yesFrontiers in Cardiovascular Medicine, 2023
BackgroundHypoxia plays a vital role throughout the whole process of atherosclerotic vulnerable plaque formation, which may be induced by a reduced oxygen supply.
Jia-Yu Wang   +4 more
doaj   +1 more source

The Role of Matrix Metalloproteinase-9 in Atherosclerotic Plaque Instability

open access: yesMediators of Inflammation, 2020
Matrix metalloproteinase-9 (MMP-9) belongs to the MMP family and has been widely investigated. Excessive MMP-9 expression can enhance extracellular matrix degradation and promote plaque instability.
Tiewei Li   +5 more
doaj   +1 more source

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