Autophagy in Atherosclerosis: A Phenomenon Found in Human Carotid Atherosclerotic Plaques
Chinese Medical Journal, 2015 Background: Autophagy has been found to be involved in animal and cell models of atherosclerosis, but to date, it lacks general observation in human atherosclerotic plaques. Here, we investigated autophagy in smooth muscle cells (SMCs), endothelial cells
Huihui Liu +6 more
doaj +1 more source
Sleep apnea-COPD overlap syndrome is associated with larger left carotid atherosclerotic plaques
Frontiers in Cardiovascular Medicine, 2023 BackgroundLittle is known about whether the overlap syndrome (OS) combining features of chronic obstructive pulmonary disease (COPD) and sleep apnea-hypopnea syndrome increases the risk of stroke associated with COPD itself.MethodsWe prospectively ...
Pedro Landete +9 more
doaj +1 more source
Macrophage autophagy in atherosclerosis [PDF]
, 2013 Macrophages play crucial roles in atherosclerotic immune responses. Recent investigation into macrophage autophagy (AP) in atherosclerosis has demonstrated a novel pathway through which these cells contribute to vascular inflammation.
Carnuccio, R. +5 more
core +2 more sources
Proteomic analysis of atherosclerotic plaque
Biomedicine & Pharmacotherapy, 2010 Proteins play a fundamental role in the formation and progression of plaque, but proteomic analysis of plaque as a whole is difficult, due to its heterogeneous cellular composition and an abundance of plasma proteins. Several approaches to this problem are reported in the literature; they include proteomic analysis of vascular tissues, analysis of ...
PORCELLI B. +9 more
openaire +6 more sources
Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque [PDF]
, 2018 Experimental studies showed that gut-derived lipopolysaccharide (LPS) is pro-atherogenic, however, its relationship with human atherosclerosis is still to be defined.
Cammisotto, Vittoria +11 more
core +2 more sources
Chromosomal alterations in atherosclerotic plaques
Atherosclerosis, 2001 Alterations of chromosomes 7 and 11 have been involved in the progression of atherosclerosis. Twenty-three carotid endarterectomy specimens were studied for the presence of alterations in chromosomes 7 and 11, and fibroblastic growth factor-3 (FGF-3) gene amplification.
L. Matturri +8 more
openaire +4 more sources
Cathepsin Activity-Based Probes and Inhibitor for Preclinical Atherosclerosis Imaging and Macrophage Depletion. [PDF]
PLoS ONE, 2016 Cardiovascular disease is the leading cause of death worldwide, mainly due to an increasing prevalence of atherosclerosis characterized by inflammatory plaques.
Ihab Abd-Elrahman +8 more
doaj +1 more source
Frontiers in Physiology, 2021 Background: The three-dimensional (3D) geometry of coronary atherosclerotic plaques is associated with plaque growth and the occurrence of coronary artery disease. However, there is a lack of studies on the 3D geometric properties of coronary plaques. We
Haipeng Liu +13 more
doaj +1 more source
Human serum albumin nanoparticles loaded with phthalocyanine dyes for potential use in photodynamic therapy of atherosclerotic plaques [PDF]
, 2019 Diseases caused by obstruction or rupture of vulnerable plaques in the arterial walls such as cardiovascular infarction or stroke are the leading cause of death in the world.
Aljarilla, Ana +14 more
core +1 more source
A Proteomic Study of Atherosclerotic Plaques in Men with Coronary Atherosclerosis
Diagnostics, 2019 Background: To study the changes in protein composition of atherosclerotic plaques at different stages of their development in coronary atherosclerosis using proteomics.
Ekaterina M. Stakhneva +9 more
doaj +1 more source