Results 81 to 90 of about 118,937 (337)

Arterial pathology in canine mucopolysaccharidosis-I and response to therapy. [PDF]

, 2011
Mucopolysaccharidosis-I (MPS-I) is an inherited deficiency of α-L-iduronidase (IdU) that causes lysosomal accumulation of glycosaminoglycans (GAG) in a variety of parenchymal cell types and connective tissues.
Dickson, Patricia I, Ellinwood, N Matthew, Kakkis, Emil D, Lyons, Jeremiah A, McEntee, Michael F, Passage, Merry B, Wall, Jonathan S   +6 more
core   +3 more sources

Uniting 4D Printing and Melt Electrowriting for the Enhancement of Regenerative Small Diameter Vascular Grafts

Advanced Healthcare Materials, EarlyView.
A hybrid 4D printing strategy enables the fabrication of shape‐morphing, mechanically reinforced tubular constructs for vascular tissue engineering. By combining alginate‐methylcellulose hydrogels with melt electrowritten polycaprolactone fibers and protein‐based functionalization, this platform supports spatially organized co‐cultures of fibroblasts ...
Max von Witzleben, Akvilė Gasiūnaitė, Marlene Ihle, Ashwini Rahul Akkineni, Kathleen Schütz, Tilman Ahlfeld, Michael Gelinsky, Anja Lode, Sarah Duin   +8 more
wiley   +1 more source

B Lymphocytes and Macrophages in the Perivascular Adipose Tissue Are Associated With Coronary Atherosclerosis: An Autopsy Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Macrophages and T lymphocytes in the perivascular adipose tissue (PvAT) were previously linked to coronary artery disease. However, the role of these cells and B lymphocytes in the human PvAT adjacent to unstable atherosclerotic plaques has ...
Daniela Souza Farias‐Itao, Carlos Augusto Pasqualucci, Aline Nishizawa, Luiz Fernando Ferraz da Silva, Fernanda Marinho Campos, Márcio Sommer Bittencourt, Karen Cristina Souza da Silva, Renata Elaine Paraízo Leite, Lea Tenenholz Grinberg, Renata Eloah de Lucena Ferretti‐Rebustini, Wilson Jacob‐Filho, Claudia Kimie Suemoto   +11 more
doaj   +1 more source

A Patient‐Specific 3D Printed Carotid Artery Model Integrating Vascular Structure, Flow, and Endothelium Responses

Advanced Healthcare Materials, EarlyView.
This study introduces the first miniaturized, patient‐specific carotid artery model created via 3D printing using GelMA with embedded vascular cells. Combining CFD, PIV, and flow perfusion, the model replicates anatomically dependent hemodynamics and cellular responses.
Jorge A. Catano, Louis Jun Ye Ong, Mingyang Yuan, Yunkun Qu, Jessica Benitez, Prasad KDV Yarlagadda, Yi‐Chin Toh, Zhiyong Li   +7 more
wiley   +1 more source

Mechanical Assessment in Atherosclerosis Based on Photoacoustic Viscoelasticity Imaging

Photonics
Early identification of vulnerable plaques is a major challenge in diagnosis and assessment of atherosclerosis. In atherosclerotic plaque development, the proportion change in components caused plaque mechanical property change and induced plaque rupture.
Xingchao Zhang, Xiaohan Shi, Hui Wu, Caixun Bai, Junshan Xiu, Yue Zhao   +5 more
doaj   +1 more source

Increased platelet reactivity is associated with circulating platelet-monocyte complexes and macrophages in human atherosclerotic plaques. [PDF]

PLoS ONE, 2014
Platelet reactivity, platelet binding to monocytes and monocyte infiltration play a detrimental role in atherosclerotic plaque progression. We investigated whether platelet reactivity was associated with levels of circulating platelet-monocyte complexes (
Bert Rutten, Claudia Tersteeg, Joyce E P Vrijenhoek, Thijs C van Holten, Ellen H A M Elsenberg, Elske M Mak-Nienhuis, Gert Jan de Borst, J Wouter Jukema, Nico H J Pijls, Johannes Waltenberger, Anton Jan van Zonneveld, Frans L Moll, Elizabeth McClellan, Andrew Stubbs, Gerard Pasterkamp, Imo Hoefer, Philip G de Groot, Mark Roest   +17 more
doaj   +1 more source

Orthopedic surgery increases atherosclerotic lesions and necrotic core area in ApoE-/- mice [PDF]

, 2016
Background and aims Observational studies show a peak incidence of cardiovascular events after major surgery. For example, the risk of myocardial infarction increases 25-fold early after hip replacement.
Chen, Cohen, Corrales-Medina, Dutta, Dutta, Gualandro, Hans W.M. Niessen, Hanson, Ilse P.A. Zethof, Janssen, Kaynar, King, Kleemann, Lalmohamed, Landesberg, Lars F.H. Theyse, Libby, Martine C. Morrison, Moore, Morrison, Naghavi, Paul A.J. Krijnen, Reid, Rianne van der Linden, Robert Kleemann, Santos-Gallego, Santos-Gallego, Santos-Gallego, Seimon, Smeeth, Tan, Thompson, Thompson, Van der Donckt, van Dijk, Virmani, Virmani, Wessel W. Fuijkschot, Yvo M. Smulders, Zhang   +39 more
core   +1 more source

Seeing inside the Body Using Wearable Sensing and Imaging Technologies

Advanced Healthcare Materials, EarlyView.
This review explores wearable technologies for noninvasive internal health monitoring. It categorizes approaches into indirect sensing (e.g., bioelectrical and biochemical signals) and direct imaging (e.g., wearable ultrasound and EIT), highlighting multimodal integration and system‐level innovation toward personalized, continuous healthcare.
Sumin Kim, Seunghun Han, Sehwan Park, Jahyun Koo   +3 more
wiley   +1 more source

Vascularized and Perfusable Human Heart‐on‐a‐Chip Model Recapitulates Aspects of Myocardial Ischemia and Enables Analysis of Nanomedicine Delivery

Advanced Materials, EarlyView.
This novel 3D human ischemic heart‐on‐a‐chip, with perfusable vasculature directly interfaced with myocardial tissue, replicates key aspects of ischemic heart injury. It also demonstrates the targeted delivery and therapeutic efficacy of cardiac homing peptide‐conjugated liposomes, validating the platform for drug and nanomedicine screening in ...
Junyoung Kim, Xuening Zhang, Richard Wang, Adrian Najer, Qiao You Lau, Ana Cammack‐Najera, Jang Ah Kim, Yoo Kyung Kang, Ruoxiao Xie, Hyemin Kim, Kai Xie, Hyeonji Lim, Tae‐Eun Park, Jinmyoung Joo, Molly M. Stevens   +14 more
wiley   +1 more source

Effect of Vascepa (icosapent ethyl) on progression of coronary atherosclerosis in patients with elevated triglycerides (200-499 mg/dL) on statin therapy: Rationale and design of the EVAPORATE study. [PDF]

, 2018
Despite reducing progression and promoting regression of coronary atherosclerosis, statin therapy does not fully address residual cardiovascular (CV) risk.
Brent Muhlestein, J, Budoff, Matthew, Le, Viet T, May, Heidi T, Nelson, John R, Roy, Sion   +5 more
core   +2 more sources