Results 51 to 60 of about 1,872,355 (352)

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Mapping malaria seasonality in Madagascar using health facility data

BMC Medicine, 2020
Background Many malaria-endemic areas experience seasonal fluctuations in case incidence as Anopheles mosquito and Plasmodium parasite life cycles respond to changing environmental conditions.
Michele Nguyen, Rosalind E. Howes, Tim C.D. Lucas, Katherine E. Battle, Ewan Cameron, Harry S. Gibson, Jennifer Rozier, Suzanne Keddie, Emma Collins, Rohan Arambepola, Su Yun Kang, Chantal Hendriks, Anita Nandi, Susan F. Rumisha, Samir Bhatt, Sedera A. Mioramalala, Mauricette Andriamananjara Nambinisoa, Fanjasoa Rakotomanana, Peter W. Gething, Daniel J. Weiss   +19 more
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Análisis de la apariencia de los recubrimientos y ensayos de durabilidad de defectos inducidos en superficies usando un sistema de análisis de proceso de captación digital de imágenes

Revista de Metalurgia, 2003
No hay técnicas establecidas o aceptadas para una caracterización precisa de los cambios de apariencia dados por los rayones profundos y daños superficiales en los recubrimientos.
F. Lee, B. Pourdeyhimi, C. Hazzard, J. Summerville   +3 more
doaj   +1 more source

Donepezil Treatment of Hypersomnia After COVID-19

Türk Nöroloji Dergisi, 2021
The long-term effects of coronavirus disease-2019 (COVID-19) are not yet fully understood and some are due to central nervous system involvement. COVID-19 was reported to cause fatigue in some people after a long-term viral illness, characterized by ...
Demet Aygün Üstel, Pervin İşeri, Meltem Can İke   +2 more
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Identifying mental health status using deep neural network trained by visual metrics

Translational Psychiatry, 2020
Mental health is an integral part of the quality of life of cancer patients. It has been found that mental health issues, such as depression and anxiety, are more common in cancer patients. They may result in catastrophic consequences, including suicide.
Somayeh B. Shafiei, Zaeem Lone, Ahmed S. Elsayed, Ahmed A. Hussein, Khurshid A. Guru   +4 more
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Integrating gamification in design research: a pedagogical approach for design education in India

Discover Education
Gamification is gaining prominence in design education, offering innovative methods to enhance student engagement and develop critical competencies such as collaboration, creativity, and problem-solving.
Ishi Srivastava, Heena Sachdeva, Shirali Tyabji   +2 more
doaj   +1 more source