Results 61 to 70 of about 1,844,619 (306)

A malaria seasonality dataset for sub-Saharan Africa

Scientific Data
Malaria imposes a significant global health burden and remains a major cause of child mortality in sub-Saharan Africa. In many countries, malaria transmission varies seasonally.
Francesca Sanna, Suzanne H. Keddie, Tara Boyhan, Paulina A. Dzianach, Michael McPhail, Julia Seitz, Thomas Nguyen, Adrian Redpath, Twatasha Chikolwa, Annie J. Browne, Jailos Lubinda, Adam Saddler, Sarah Hafsia, Rubi Jayaseelen, Hunter S. Baggen, Jennifer A. Rozier, Tasmin L. Symons, Joseph Harris, Sarah Connor, Camilo Vargas, Charles Whittaker, Michele Nguyen, Peter W. Gething, Daniel J. Weiss   +23 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Técnicas regionales guiadas por ultrasonido para manejo de analgesia para cesárea [PDF]

Revista Chilena de Anestesia, 2022
Pablo Santillán Roldan, Andrea Campoverde Cajamarca, Lorena Guacales Zambrano, Andrés Cepeda Mora, Pablo Armas Cruz, Geraldine Paredes   +5 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Atlas

Dictionnaire de la Ferme générale (1640-1794), 2023
Atlas ist ein elektrisches Lastenmotorrad, welches dank seiner tiefliegenden Ladefläche ein verbessertes Fahrverhalten hat. Begünstigt wird dieses durch ein zentrales Drehgelenk, das die Ladefläche mit dem Hauptkörper verbindet. Es kann auf seiner 55cm x 36cm breiten Ladefläche Lasten von bis zu 90kg transportieren und hat eine Reichweite von 200km. Am
openaire   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Sustainability-oriented assessment of external thermal insulation composite systems: A case study from Poland

Cogent Engineering, 2021
External Thermal Insulation Composite System (ETICS) technology is commonly used to insulate buildings to increase the energy efficiency of external building envelopes.
Bartosz Michałowski, Jacek Michalak
doaj   +1 more source

The Stony Brook / SMARTS Atlas of mostly Southern Novae

, 2012
We introduce the Stony Brook / SMARTS Atlas of (mostly) Southern Novae. This atlas contains both spectra and photometry obtained since 2003. The data archived in this atlas will facilitate systematic studies of the nova phenomenon and correlative studies
Andrew Battisti, Bode M. F., Bond H. E., Dworetsky M. M., Frederick M. Walter, Guy S. Stringfellow, Howard E. Bond, Hughes J. P., Hung L. W., Liller W., Liller W., McLaughlin D. B., Naik S., Nakano S., Patterson J., Payne-Gaposchkin C., Read A. M., Sarah E. Towers, Seach J., Silviero A., Smak J. I., Starrfield S., Walter F. M.   +22 more
core   +1 more source