Results 61 to 70 of about 609,289 (305)

Survey of switching techniques in high-speed networks and their performance [PDF]

open access: yes, 1989
One of the most promising approaches for high speed networks for integrated service applications is fast packet switching, or ATM (Asynchronous Transfer Mode).
Kolson, David   +4 more
core  

Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis [PDF]

open access: yes, 2020
The DNA damage response (DDR) comprises multiple functions that collectively preserve genomic integrity and suppress tumorigenesis. The Mre11 complex and ATM govern a major axis of the DDR and several lines of evidence implicate that axis in tumor ...
Burgers, Peter M   +11 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Influence Of Interior Design To Prevent Crime Actions In Autimatic Teller Machine (ATM) Room [PDF]

open access: yes, 2019
This study departs from the phenomenon of increasing crime that occurred at the Automatic Teller Machine (ATM). The rise of crime at ATMs does not only occur in Indonesia, but almost all over the world.
Hanom, I. (Imtihan )   +3 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Minimum-risk path planning based on hazardous weather uncertainty

open access: yes工程科学学报
Hazardous weather, such as thunderstorms, icing, and turbulence, is one of the main causes of flight accidents. To avoid possible risks caused by temporary diversion of hazardous weather during flight, numerical and probabilistic forecasting are employed
Yantao WANG, Xinyi ZHAO
doaj   +1 more source

Chemical inhibition of DNA repair kinases as a promising tool in oncology

open access: yesBiomedical Papers, 2016
Background: DNA repair pathways play a major role in tumour resistance towards chemo- and radiotherapy. Therefore, inhibitors of specific DNA repair pathways might be advantageous when used in combination with DNA-damaging agents, such as ionizing ...
Kamila Durisova   +3 more
doaj   +1 more source

Parametrization of the precipitation in the Northern Hemisphere and its verification in Mexico [PDF]

open access: yesAnnales Geophysicae, 1998
To improve results in monthly rainfall prediction, a parametrization of precipitation has been developed. The thermodynamic energy equation used in the Adem thermodynamic model (ATM) and the Clausius and Clapeyron equation, were used to obtain a ...
V. M. Mendoza, B. Oda, J. Adem
doaj   +1 more source

Analysis-of-marginal-Tail-Means (ATM): a robust method for discrete black-box optimization

open access: yes, 2018
We present a new method, called Analysis-of-marginal-Tail-Means (ATM), for effective robust optimization of discrete black-box problems. ATM has important applications to many real-world engineering problems (e.g., manufacturing optimization, product ...
Mak, Simon, Wu, C. F. Jeff
core   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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