Results 51 to 60 of about 609,289 (305)

ATM meets ERK5

Aging, 2017
The complexity of the living cell is supported by the multitasking activity of its protein constituents. The kinase Ataxia Telangiectasia Mutated ATM)is a clear example. Not only does it orchestrate the DNA damage response but also sustains cellular homeostasis, including metabolism, control of oxidative stress, autophagy and apoptosis [1]. [...]
Angulo Ibáñez, María, Espel Masferrer, Enric, Rovira Clavé, Xavier   +2 more
openaire   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Large-scale scattering-augmented optical encryption

Nature Communications
Data proliferation in the digital age necessitates robust encryption techniques to protect information privacy. Optical encryption leverages the multiple degrees of freedom inherent in light waves to encode information with parallel processing and ...
Liheng Bian, Xuyang Chang, Shaowei Jiang, Liming Yang, Xinrui Zhan, Shicong Liu, Daoyu Li, Rong Yan, Zhen Gao, Jun Zhang   +9 more
doaj   +1 more source

Survey of traffic control schemes and error control schemes for ATM networks [PDF]

, 1991
Among the techniques proposed for B-ISDN transfer mode, ATM concept is considered to be the most promising transfer technique because of its flexibility and efficiency. This paper surveys and reviews a number of topics related to ATM networks.
Bae, Jaime Jungok, Suda, Tatsuya
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Biología del fibrocartílago articular frente a las demandas funcionales

Odontología Sanmarquina, 2005
La demanda funcional de la Articulación Temporomandibular requiere de una adecuada respuesta biológica de los tejidos que recubren las superficies articulares y el disco, los cuales son interdependientes en lo funcional y estructural juntamente con el ...
Luis H. Gálvez
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Energy Efficient Relay-Assisted Cellular Network Model using Base Station Switching [PDF]

, 2012
Cellular network planning strategies have tended to focus on peak traffic scenarios rather than energy efficiency. By exploiting the dynamic nature of traffic load profiles, the prospect for greener communications in cellular access networks is evolving.
Alam, Atm S., Dooley, Laurence S., Poulton, Adrian S.   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Physical twinning for joint encoding-decoding optimization in computational optics: a review

Light: Science & Applications
Computational optics introduces computation into optics and consequently helps overcome traditional optical limitations such as low sensing dimension, low light throughput, low resolution, and so on.
Liheng Bian, Xinrui Zhan, Rong Yan, Xuyang Chang, Hua Huang, Jun Zhang   +5 more
doaj   +1 more source