Results 81 to 90 of about 3,054,495 (336)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
LAWS OF FORMATION OF CHEMICAL COMPOSITION OF THE ATMOSPHERE IN THE TERRITORY OF KAZAN
Юг России: экология, развитие, 2016 Aim. We made a comprehensive assessment of the pollution level of the atmosphere in Kazan; studied the effect of meteorological variables and phenomena in the formation of the level of pollution of the atmosphere of a big city, studied areas of ...
Yu. R. Yanglicheva, G. R. Valeeva
doaj +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Eos, Transactions American Geophysical Union, 1991 Theoretical understanding of the upper atmosphere and the complex physical processes responsible for its composition, dynamics, and thermal behavior has improved to the point where reasonable three‐dimensional, time‐dependent models of the atmosphere above about 100 km exist.
Siscoe, George L., Killeen, Timothy L.
openaire +2 more sources
Measurement of plant xylem water pressure using the high-capacity tensiometer and implications for the modelling of soil–atmosphere interaction [PDF]
, 2020 Roberta Dainese, Alessandro Tarantino
openalex +1 more source
An efficient Monte Carlo model for the slowing down of photoelectrons. Application to H-
, 2022 A. García Muñoz
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Sensors, 2020 In the last decades, the increase in global industrialization and the consequent technological progress have damaged the quality of the environment.
Valeria De Matteis +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
, 2018 We present a near-infrared spectro-interferometric observation of the non-Mira-type, semiregular asymptotic giant branch star SW Vir. Our aim is to probe the physical properties of the outer atmosphere with spatially resolved data in individual molecular
Berna, M. Y. L. Maluenda +2 more
core +1 more source