Results 61 to 70 of about 484,393 (291)

A fast stratospheric chemistry solver: the E4CHEM submodel for the atmospheric chemistry global circulation model EMAC [PDF]

Geoscientific Model Development, 2010
The atmospheric chemistry general circulation model ECHAM5/MESSy (EMAC) and the atmospheric chemistry box model CAABA are extended by a computationally very efficient submodel for atmospheric chemistry, E4CHEM.
A. J. G. Baumgaertner, P. Jöckel, B. Steil, H. Tost, R. Sander   +4 more
doaj   +1 more source

Atmospheric chemistry

Eos, Transactions American Geophysical Union, 1971
The current intense concern with environmental quality in the United States has resulted in maintaining or possibly even increasing the amount of research in atmospheric chemistry in a period of scientific retrenchment. Thus there has been increasing emphasis during the last few years on the use of chemistry to determine effects of mankind on the earth'
openaire   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

How does the local wind field control the aerosol distribution in coastal Dronning Maud Land? [PDF]

, 2011
Atmospheric circulation patterns and chemical concentrations in firn cores are highly related to each other. Atmospheric winds transport aerosols like sea salt and mineral dust over the globe and redistribute them.
Bigler, M., Fischer, Hubertus, Schmidt, Katrin, Wegner, Anna, Weller, Rolf   +4 more
core  

Atmosphere-Ocean Ozone Exchange – A Global Modeling Study of Biogeochemical, Atmospheric and Water-Side Turbulence Dependencies [PDF]

, 2009
The significance of the removal of tropospheric ozone by the oceans, covering ~2/3 of the Earth's surface, has only been addressed in a few studies involving water tank, aircraft, and tower flux measurements.
Fairall, C.W., Ganzeveld, L.N., Hare, J., Helmig, D., Pozzer, A.   +4 more
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Technical note: The new comprehensive atmospheric chemistry module MECCA [PDF]

Atmospheric Chemistry and Physics, 2005
In this technical note we present the multi-purpose atmospheric chemistry model MECCA. Owing to its versatility and modular structure, it can be used for tropospheric as well as stratospheric chemistry calculations. Extending the code to other domains
R. Sander, A. Kerkweg, P. Jöckel, J. Lelieveld   +3 more
doaj  

A Global/Regional Integrated Model System‐Chemistry Climate Model: 1. Simulation Characteristics

Earth and Space Science, 2019
This study describes the simulation characteristics of a newly developed Global/Regional Integrated Model system‐Chemistry Climate Model (GRIMs‐CCM), which is listed in Chemistry Climate Model Initiative as a participating model.
Yong‐Cheol Jeong, Sang‐Wook Yeh, Seungun Lee, Rokjin J. Park   +3 more
doaj   +1 more source

Subpolar Activation of Halogen Heterogeneous Chemistry in Austral Spring

Geophysical Research Letters, 2021
Heterogeneous halogen chemistry plays a dominant role in driving changes in polar chemical composition and ozone depletion. Activation of halogens outside the polar regions may result in depletion of local ozone, along with changes in the chemical ...
Brian Zambri, Douglas E. Kinnison, Susan Solomon   +2 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source