Results 61 to 70 of about 2,918,823 (240)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Atmospheric Chemistry Signatures of an Equatorially Symmetric Matsuno–Gill Circulation Pattern

, 2021
© 2020 American Meteorological Society. For information regarding reuse of this content and general copyright information, consult the AMS Copyright Policy (www.ametsoc.org/PUBSReuseLicenses).
Wilka, Catherine, Garcia, Rolando, Cronin, Timothy W, Wilka, Catherine Anne, Solomon, Susan, Cronin, Timothy Wallace, Kinnison, Doug   +6 more
core   +1 more source

A three-dimensional atmospheric dispersion model for Mars

Progress in Earth and Planetary Science, 2021
Atmospheric local-to-regional dispersion models are widely used on Earth to predict and study the effects of chemical species emitted into the atmosphere and to contextualize sparse data acquired at particular locations and/or times. However, to date, no
D. Viúdez-Moreiras
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The Impact of Cometary “Impacts” on the Chemistry, Climate, and Spectra of Hot Jupiter Atmospheres

The Astrophysical Journal
Impacts from icy and rocky bodies have helped shape the composition of Solar System objects; for example, the Earth–Moon system, or the recent impact of comet Shoemaker–Levy 9 with Jupiter.
F. Sainsbury-Martinez, C. Walsh
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

A Global/Regional Integrated Model System‐Chemistry Climate Model: 1. Simulation Characteristics

Earth and Space Science, 2019
This study describes the simulation characteristics of a newly developed Global/Regional Integrated Model system‐Chemistry Climate Model (GRIMs‐CCM), which is listed in Chemistry Climate Model Initiative as a participating model.
Yong‐Cheol Jeong, Sang‐Wook Yeh, Seungun Lee, Rokjin J. Park   +3 more
doaj   +1 more source

Four-dimensional variational data assimilation for inverse modelling of atmospheric methane emissions: method and comparison with synthesis inversion [PDF]

, 2008
A four-dimensional variational (4D-Var) data assimilation system for inverse modelling of atmospheric methane emissions is presented. The system is based on the TM5 atmospheric transport model.
Bergamaschi, P., M. C. Krol, P. Bergamaschi, J. F. Meirink, Krol, M.C., Dep Natuurkunde, Meirink, J., Marine and Atmospheric Research, Meirink, J.F., Krol, M. C., Meirink, J. F.   +10 more
core   +3 more sources

Subpolar Activation of Halogen Heterogeneous Chemistry in Austral Spring

Geophysical Research Letters, 2021
Heterogeneous halogen chemistry plays a dominant role in driving changes in polar chemical composition and ozone depletion. Activation of halogens outside the polar regions may result in depletion of local ozone, along with changes in the chemical ...
Brian Zambri, Douglas E. Kinnison, Susan Solomon   +2 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source