Results 51 to 60 of about 2,918,823 (240)

A Fast, Parallelized, GPU-accelerated Photochemical Model, XODIAC, with Built-in Equilibrium Chemistry and Multiple Chemical Networks for Exoplanetary Atmospheres

The Astrophysical Journal
The launch of the James Webb Space Telescope has delivered high-quality atmospheric observations and expanded the known chemical inventory of exoplanetary atmospheres, opening new avenues for atmospheric chemistry modeling to interpret these data.
Priyankush Ghosh, Sambit Mishra, Shubham Dey, Debayan Das, P. B. Rimmer, Liton Majumdar   +5 more
doaj   +1 more source

A química atmosférica no Brasil de 1790 a 1853

Química Nova, 2010
Atmospheric chemistry in Brazil from 1790 to 1853. Scarcely any mention is made today of investigations carried out in Brazil during the period above on the science of the atmosphere.
Adílio Jorge Marques, Carlos A. L. Filgueiras   +1 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Zeeman: A Deep Learning Framework for Regional Atmospheric Chemistry Forecasting

Geophysical Research Letters
Atmospheric chemistry encapsulates the emission of various pollutants, the complex chemistry reactions, and the meteorology dominant transport, which form a dynamic system that governs air quality.
Mijie Pang, Jianbing Jin, Arjo Segers, Hai Xiang Lin, Guoqiang Wang, Hong Liao, Wei Han   +6 more
doaj   +1 more source

History of Atmospheric Chemistry in Switzerland

CHIMIA
This paper presents an overview on atmospheric chemistry, beginning with international aspects since the Roman Empire, and then focusing on the developments in Switzerland.
Urs Baltensperger
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Multi-model simulations of the impact of international shipping on Atmospheric Chemistry and Climate in 2000 and 2030 [PDF]

, 2007
The global impact of shipping on atmospheric chemistry and radiative forcing, as well as the associated uncertainties, have been quantified using an ensemble of ten state-of-the-art atmospheric chemistry models and a predefined set of emission data.
COLLINS W.J., LAWRENCE M., J. M. Rodriguez, Dentener, F. J., Isaksen, Ivar S. A., Butler, Tim, Richter, Andreas, Collins, W. J., Gauss, Michael, BUTLER T., EYRING Veronika, K. Sudo, Isaksen, I.S.A., Lawrence, M.G., Isaksen, I. S. A., LAUER Axel, ELLINGSEN K., Stevenson, D. S., van Noije, T.P.C., Dentener, Frank J., M. G. Lawrence, K. Ellingsen, VAN NOIJE T., HAUGLUSTAINE D., Lawrence, M. G., Strahan, S. E., Hauglustaine, Didier A., van Noije, Twan P.C., Szopa, S., A. Richter, Stevenson, D.S., M. Gauss, Sud, K., Collins, William J., van Noije, T. P. C., Lauer, A., I. S. A. Isaksen, Wild, Olivier, SZOPA S., Rodriguez, J. M., STEVENSON D.S., SUDO K., Lawrence, Mark G., Wild, O., Ellingsen, Kirsten, GAUSS M., Sudo, K., Lauer, Axel, WILD O., Strahan, Susan E., Hauglustaine, D. A., M. Sanderson, S. Szopa, S. E. Strahan, A. Lauer, T. P. C. van Noije, Stevenson, David; id_orcid, Laval-Szopa, Sophie, V. Eyring, O. Wild, Eyring, V., D. A. Hauglustaine, DENTENER Franciscus, D. S. Stevenson, T. Butler, Sanderson, M., Sudo, Kengo, W. J. Collins, RICHTER A., F. J. Dentener, Strahan, S.E., Ellingsen, K., Hauglustaine, D.A., Butler, T., Dentener, F.J., Eyring, Veronika, SANDERSON M.G., Sanderson, Michael, STRAHAN S., Collins, W.J., Stevenson, David S., Gauss, M., Rodriguez, J.M., Richter, A., ISAKSEN I.S.A., RODRIGUEZ J. M.   +85 more
core   +3 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source