Results 41 to 50 of about 484,393 (291)

Implementation of the chemistry module MECCA (v2.5) in the modal aerosol version of the Community Atmosphere Model component (v3.6.33) of the Community Earth System Model [PDF]

open access: yesGeoscientific Model Development, 2013
A coupled atmospheric chemistry and climate system model was developed using the modal aerosol version of the National Center for Atmospheric Research Community Atmosphere Model (modal-CAM; v3.6.33) and the Max Planck Institute for Chemistry's Module ...
M. S. Long   +7 more
doaj   +1 more source

Lookup tables to compute high energy cosmic ray induced atmospheric ionization and changes in atmospheric chemistry

open access: yes, 2010
A variety of events such as gamma-ray bursts and supernovae may expose the Earth to an increased flux of high-energy cosmic rays, with potentially important effects on the biosphere. Existing atmospheric chemistry software does not have the capability of
Adrian L Melott   +11 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Modeling chemistry in and above snow at Summit, Greenland – Part 1: Model description and results [PDF]

open access: yes, 2011
Sun-lit snow is increasingly recognized as a chemical reactor that plays an active role in uptake, transformation, and release of atmospheric trace gases.
Dibb, JE   +6 more
core   +3 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Influence of biogenic NO emissions from soil on atmospheric chemistry over Africa: a regional modelling study [PDF]

open access: yesAtmospheric Chemistry and Physics
In the context of climate change and increasing anthropogenic pressures in Africa, understanding the interactions between atmospheric chemistry, regional climate, and biogeochemical cycles is critical.
E. M. Yao   +8 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Atmospheric chemistry enhances the climate mitigation potential of tree restoration

open access: yesCommunications Earth & Environment
Although tree restoration, including reforestation and afforestation, can enhance carbon sequestration and help mitigate climate change, this negative forcing can be strengthened or weakened through non-carbon cycle biogeophysical factors, including ...
Robert J. Allen   +8 more
doaj   +1 more source

History of Atmospheric Chemistry in Switzerland

open access: yesCHIMIA
This paper presents an overview on atmospheric chemistry, beginning with international aspects since the Roman Empire, and then focusing on the developments in Switzerland.
Urs Baltensperger
doaj   +1 more source

Modelling the Inorganic Bromine Partitioning in the Tropical Tropopause over the Pacific Ocean [PDF]

open access: yes, 2016
The stratospheric inorganic bromine burden (Bry) arising from the degradation of brominated very short-lived organic substances (VSL org ), and its partitioning between reactive and reservoir species, is needed for a comprehensive assessment of the ozone
Atlas, Elliot   +13 more
core   +1 more source

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